-
1
-
-
80054993341
-
Linking pharmacology to cl inical reports: Cy clobenzaprine and its po ssible association with se rotonin syndrome
-
Mestres, J., Seifert, S.A. & Oprea, T.I. Linking pharmacology to cl inical reports: cy clobenzaprine and its po ssible association with se rotonin syndrome. Clin. Pharmacol. Ther. 90, 662-665 (2011).
-
(2011)
Clin. Pharmacol. Ther.
, vol.90
, pp. 662-665
-
-
Mestres, J.1
Seifert, S.A.2
Oprea, T.I.3
-
2
-
-
79952115164
-
Ligandbased approaches to in silico pharmacology
-
Vidal, D., Garcia-Serna, R. & Mestres, J. Ligandbased approaches to in silico pharmacology. Methods Mol. Biol. 672, 489-502 (2011).
-
(2011)
Methods Mol. Biol.
, vol.672
, pp. 489-502
-
-
Vidal, D.1
Garcia-Serna, R.2
Mestres, J.3
-
3
-
-
0036516054
-
Chem-bioinformatics: Comparative QSAR at the interface between chemistry and biology
-
DOI 10.1021/cr0102009
-
Hansch, C., Hoekman, D., Leo, A., Weiniger, D. & Selassie, C.D. Chembioinformatics: comparative QSAR at the interface of biology and chemistry. Chem. Rev. 102, 783-812 (2002). (Pubitemid 35377614)
-
(2002)
Chemical Reviews
, vol.102
, Issue.3
, pp. 783-812
-
-
Hansch, C.1
Hoekman, D.2
Leo, A.3
Weininger, D.4
Selassie, C.D.5
-
4
-
-
77954052283
-
Systems approaches to polypharmacology and drug discovery
-
Boran, A.D. & Iyengar, R. Systems approaches to polypharmacology and drug discovery. Curr. Opin. Drug Discov. Devel. 13, 297-309 (2010).
-
(2010)
Curr. Opin. Drug Discov. Devel.
, vol.13
, pp. 297-309
-
-
Boran, A.D.1
Iyengar, R.2
-
5
-
-
79956321442
-
Pharmacological mechanism-based drug safety assessment and prediction
-
Abernethy, D.R., Woodcock, J. & Lesko, L.J. Pharmacological mechanism-based drug safety assessment and prediction. Clin. Pharmacol. Ther. 89, 793-797 (2011).
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 793-797
-
-
Abernethy, D.R.1
Woodcock, J.2
Lesko, L.J.3
-
6
-
-
33749335282
-
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
-
DOI 10.1126/science.1132939
-
Lamb, J. et al. The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313, 1929-1935 (2006). (Pubitemid 44497995)
-
(2006)
Science
, vol.313
, Issue.5795
, pp. 1929-1935
-
-
Lamb, J.1
Crawford, E.D.2
Peck, D.3
Modell, J.W.4
Blat, I.C.5
Wrobel, M.J.6
Lerner, J.7
Brunet, J.-P.8
Subramanian, A.9
Ross, K.N.10
Reich, M.11
Hieronymus, H.12
Wei, G.13
Armstrong, S.A.14
Haggarty, S.J.15
Clemons, P.A.16
Wei, R.17
Carr, S.A.18
Lander, E.S.19
Golub, T.R.20
more..
-
7
-
-
77952742187
-
Kinase inhibition-related adverse events predicted from in vitro kinome and clinical trial data
-
Yang, X., Huang, Y., Crowson, M., Li, J., Maitland, M.L. & Lussier, Y.A. Kinase inhibition-related adverse events predicted from in vitro kinome and clinical trial data. J. Biomed. Informatics 43, 376-384 (2010).
-
(2010)
J. Biomed. Informatics
, vol.43
, pp. 376-384
-
-
Yang, X.1
Huang, Y.2
Crowson, M.3
Li, J.4
Maitland, M.L.5
Lussier, Y.A.6
-
8
-
-
75549085923
-
Off-target networks derived from ligand set similarity
-
Keiser, M.J. & Hert, J. Off-target networks derived from ligand set similarity. Methods Mol. Biol. 575, 195-205 (2009).
-
(2009)
Methods Mol. Biol.
, vol.575
, pp. 195-205
-
-
Keiser, M.J.1
Hert, J.2
-
9
-
-
77953304931
-
Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo Warfarin Effectiveness Study)
-
Epstein, R.S. et al. Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo Warfarin Effectiveness Study). J. Am. Coll. Cardiol. 55, 2804-2812 (2010).
-
(2010)
J. Am. Coll. Cardiol.
, vol.55
, pp. 2804-2812
-
-
Epstein, R.S.1
-
10
-
-
79851472033
-
Developing the Sentinel System - A national resource for evidence development
-
Behrman, R.E., Benner, J.S., Brown, J.S., McClellan, M., Woodcock, J. & Platt, R. Developing the Sentinel System - a national resource for evidence development. N. Engl. J. Med. 364, 498-499 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 498-499
-
-
Behrman, R.E.1
Benner, J.S.2
Brown, J.S.3
McClellan, M.4
Woodcock, J.5
Platt, R.6
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