Palmerolide macrolides from the Antarctic tunicate Synoicum adareanum

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 22, 2011, Pages 6608-6614

  Noguez, Jaime H ^a   Diyabalanage, Thushara K K ^a   Miyata, Yoshinari ^a   Xie, Xiao Song ^b   Valeriote, Frederick A ^c   Amsler, Charles D ^d   McClintock, James B ^d   Baker, Bill J ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c HENRY FORD HEALTH SYSTEM   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Melanoma; Polyketide; V ATPase inhibitor

Indexed keywords

MACROLIDE; PALMEROLIDE A; PALMEROLIDE D; PALMEROLIDE E; PALMEROLIDE F; PALMEROLIDE G; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UNCLASSIFIED DRUG;

ANTARCTICA; ANTINEOPLASTIC ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; MELANOMA; NONHUMAN; STRUCTURE ACTIVITY RELATION; SYNOICUM ADAREANUM; UROCHORDATA;

ANIMALS; ANTARCTIC REGIONS; ANTINEOPLASTIC AGENTS; CATTLE; HUMANS; MACROLIDES; MELANOMA; MOLECULAR CONFORMATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; STEREOISOMERISM; UROCHORDATA; VACUOLAR PROTON-TRANSLOCATING ATPASES;

MAMMALIA; SYNOICUM ADAREANUM;

EID: 80055014046     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.06.004     Document Type: Conference Paper

References (15)

1. T. Nishi, and M. Forgac Nature Rev. Mol. Cell Biol. 3 2002 94
2. M. Forgac Nature Rev. Mol. Cell Biol. 8 2007 917
3. J.A. Beutler, and T.C. McKee Curr. Med. Chem. 10 2003 787
4. X.S. Xie, D. Padron, X. Liao, J. Wang, M.G. Roth, and J.K. De Brabander J. Biol. Chem. 279 2004 19755
5. T. Diyabalanage, C.D. Amsler, J.B. McClintock, and B.J. Baker J. Am. Chem. Soc. 128 2006 5630
6. X. Jiang, B. Liu, S. Lebreton, and J.K. De Brabander J. Am. Chem. Soc. 129 2007 6386
7. K.C. Nicolaou, R. Guduru, Y.-P. Sun, B. Banerji, and D.Y.-K. Chen Angew. Chem., Int. Ed. 46 2007 5896
8. K.C. Nicolaou, Y.P. Sun, R. Guduru, B. Banerji, and D.Y. Chen J. Am. Chem. Soc. 130 2008 3633
9. Diyabalanage, T. Dissertation, University of South Florida, Tampa, 2006.
10. M. Lebar, and B.J. Baker Tetrahedron Lett. 48 2007 8009
11. I. Ohtani, T. Kusumi, Y. Kashman, and H. Kakisawa J. Am. Chem. Soc. 113 1991 4092
12. E.J. Bowman, A. Siebers, and A. Karlheinz Proc. Natl. Acad. Sci. U.S.A. 85 1988 7972
13. M.R. Boyd, C. Farina, P. Belfiore, S. Gagliardi, J.W. Kim, Y. Hayakawa, J.A. Beutler, T.C. McKee, B.J. Bowman, and E.J. Bowman J. Pharmacol. Exp. Ther. 297 2001 114
14. K.C. Nicolaou, G.Y.C. Leung, D.H. Dethe, R. Guduru, Y.-P. Sun, C.S. Lim, and D.Y.-K. Chen J. Am. Chem. Soc. 130 2008 10019
15. Goering, B. K. Ph.D. Dissertation, Cornell University, 1995.\