SCOPUS 정보 검색 플랫폼

Organic and Biomolecular Chemistry

Volumn 9, Issue 22, 2011, Pages 7814-7821

Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1

(6) Dowden, James a Pike, Richard A a Parry, Richard V b Hong, Wei a Muhsen, Usama A a Ward, Stephen G b

a UNIVERSITY OF NOTTINGHAM (United Kingdom)

b University of Bath (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL EVALUATION; BIOLOGICAL PROCESS; CANCER PROGRESSION; CHEMICAL PROBES; DYNAMIC FUNCTIONS; EPIGENETIC REGULATION; MODULAR SYNTHESIS; POST-TRANSLATIONAL MODIFICATIONS; POTENT INHIBITOR; S-ADENOSYLMETHIONINE; SMALL MOLECULE INHIBITOR; SUBSTRATE PROTEINS;

ARGININE; PROTEINS; SIGNAL TRANSDUCTION;

BINDING SITES;

ARGININE; COACTIVATOR ASSOCIATED ARGININE METHYLTRANSFERASE 1; COACTIVATOR-ASSOCIATED ARGININE METHYLTRANSFERASE 1; ENZYME INHIBITOR; HYBRID PROTEIN; PRMT1 PROTEIN, HUMAN; PROTEIN ARGININE METHYLTRANSFERASE; REPRESSOR PROTEIN; S ADENOSYLMETHIONINE;

ARTICLE; BACTERIUM TRANSFORMATION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENETIC EPIGENESIS; GENETICS; HUMAN; METABOLISM; METHYLATION; MOLECULAR WEIGHT; PLASMID; PROTEIN BINDING; PROTEIN PROCESSING; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ARGININE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; EPIGENESIS, GENETIC; ESCHERICHIA COLI; HUMANS; METHYLATION; MODELS, MOLECULAR; MOLECULAR WEIGHT; PLASMIDS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-ARGININE N-METHYLTRANSFERASES; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; S-ADENOSYLMETHIONINE; SUBSTRATE SPECIFICITY; TRANSFORMATION, BACTERIAL;

EID: 80055010291 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/c1ob06100c Document Type: Article

Times cited : (37)

References (47)

1
- 69949148388
- R. A. Copeland M. E. Solomon V. M. Richon Nat. Rev. Drug Discovery 2009 8 724 732
- (2009) Nat. Rev. Drug Discovery , vol.8 , pp. 724-732
- Copeland, R.A.¹ Solomon, M.E.² Richon, V.M.³

2
- 51949111451
- P. A. Cole Nat. Chem. Biol. 2008 4 590 597
- (2008) Nat. Chem. Biol. , vol.4 , pp. 590-597
- Cole, P.A.¹

3
- 59349115177
- B. C. Smith J. M. Denu Biochim. Biophys. Acta. 2009 1789 45 57
- (2009) Biochim. Biophys. Acta. , vol.1789 , pp. 45-57
- Smith, B.C.¹ Denu, J.M.²

4
- 38349035858
- M. T. Bedford J. Cell Sci. 2007 120 4243 4246
- (2007) J. Cell Sci. , vol.120 , pp. 4243-4246
- Bedford, M.T.¹

5
- 33749179022
- A. O. Yildirim P. Bulau D. Zakrzewicz K. E. Kitowska N. Weissmann F. Grimminger R. E. Morty O. Eickelberg Am. J. Respir. Cell Mol. Biol. 2006 35 436 443
- (2006) Am. J. Respir. Cell Mol. Biol. , vol.35 , pp. 436-443
- Yildirim, A.O.¹ Bulau, P.² Zakrzewicz, D.³ Kitowska, K.E.⁴ Weissmann, N.⁵ Grimminger, F.⁶ Morty, R.E.⁷ Eickelberg, O.⁸

6
- 33745256805
- X. Chen F. Niroomand Z. F Liu A. Zankl H. A. Katus L. Jahn C. P. Tiefenbacher Basic Res. Cardiol. 2006 101 346 353
- (2006) Basic Res. Cardiol. , vol.101 , pp. 346-353
- Chen, X.¹ Niroomand, F.² Liu, Z.F.³ Zankl, A.⁴ Katus, H.A.⁵ Jahn, L.⁶ Tiefenbacher, C.P.⁷

7
- 10644227634
- M. C. Boulanger C. Liang R. S. Russell R. T. Lin M. T. Bedford M. A. Wainberg S. Richard J. Virol. 2005 79 124 131
- (2005) J. Virol. , vol.79 , pp. 124-131
- Boulanger, M.C.¹ Liang, C.² Russell, R.S.³ Lin, R.T.⁴ Bedford, M.T.⁵ Wainberg, M.A.⁶ Richard, S.⁷

8
- 23744438500
- F. Blanchet A. Cardona F. A. Letimier M. S. Hershfield O. Acuto J. Exp. Med. 2005 202 371 377
- (2005) J. Exp. Med. , vol.202 , pp. 371-377
- Blanchet, F.¹ Cardona, A.² Letimier, F.A.³ Hershfield, M.S.⁴ Acuto, O.⁵

9
- 78649638594
- M. Yoshimatsu G. Toyokawa S. Hayami M. Unoki T. Tsunoda H. I. Field J. D. Kelly D. E. Neal Y. Maehara B. A. J. Ponder Y. Nakamura R. Hamamoto Int. J. Cancer 2011 128 562 573
- (2011) Int. J. Cancer , vol.128 , pp. 562-573
- Yoshimatsu, M.¹ Toyokawa, G.² Hayami, S.³ Unoki, M.⁴ Tsunoda, T.⁵ Field, H.I.⁶ Kelly, J.D.⁷ Neal, D.E.⁸ Maehara, Y.⁹ Ponder, B.A.J.¹⁰ Nakamura, Y.¹¹ Hamamoto, R.¹²

10
- 21744457108
- D. B. Seligson S. Horvath T. Shi H. Yu S. Tze M. Grunstein S. K. Kurdistani Nature 2005 435 1262 1266
- (2005) Nature , vol.435 , pp. 1262-1266
- Seligson, D.B.¹ Horvath, S.² Shi, T.³ Yu, H.⁴ Tze, S.⁵ Grunstein, M.⁶ Kurdistani, S.K.⁷

11
- 33748359520
- S. Majumder Y. Liu O. H. Ford J. L. Mohler Y. E. Whang Prostate 2006 66 1292 1301
- (2006) Prostate , vol.66 , pp. 1292-1301
- Majumder, S.¹ Liu, Y.² Ford, O.H.³ Mohler, J.L.⁴ Whang, Y.E.⁵

12
- 3042536209
- H. Hong C. H. Kao M. H. Jeng J. N. Eble M. O. Koch T. A. Gardner S. B. Zhang L. Li C. X. Pan Z. Q. Hu G. T. MacLennan L. Cheng Cancer 2004 101 83 89
- (2004) Cancer , vol.101 , pp. 83-89
- Hong, H.¹ Kao, C.H.² Jeng, M.H.³ Eble, J.N.⁴ Koch, M.O.⁵ Gardner, T.A.⁶ Zhang, S.B.⁷ Li, L.⁸ Pan, C.X.⁹ Hu, Z.Q.¹⁰ MacLennan, G.T.¹¹ Cheng, L.¹²

13
- 33748624090
- S. El Messaoudi E. Fabbrizio C. Rodriguez P. Chuchana L. Fauquier D. H. Cheng C. Theillet L. Vandel M. T. Bedford C. Sardet Proc. Natl. Acad. Sci. U. S. A. 2006 103 13351 56
- (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 13351-56
- Messaoudi, S.E.¹ Fabbrizio, E.² Rodriguez, C.³ Chuchana, P.⁴ Fauquier, L.⁵ Cheng, D.H.⁶ Theillet, C.⁷ Vandel, L.⁸ Bedford, M.T.⁹ Sardet, C.¹⁰

14
- 79952506432
- E. M. Bissinger R. Heinke W. Sippl M. Jung Med. Chem. Commun. 2010 1 114 124
- (2010) Med. Chem. Commun. , vol.1 , pp. 114-124
- Bissinger, E.M.¹ Heinke, R.² Sippl, W.³ Jung, M.⁴

15
- 41849105766
- T. C. Osborne R. L. Roska S. R. Rajski P. R. Thompson J. Am. Chem. Soc. 2008 130 4574 4575
- (2008) J. Am. Chem. Soc. , vol.130 , pp. 4574-4575
- Osborne, T.C.¹ Roska, R.L.² Rajski, S.R.³ Thompson, P.R.⁴

16
- 78650099217
- K. L. Bicker O. Obianyo H. L. Rust P. R. Thompson Mol. BioSyst. 2011 7 48 51
- (2011) Mol. BioSyst. , vol.7 , pp. 48-51
- Bicker, K.L.¹ Obianyo, O.² Rust, H.L.³ Thompson, P.R.⁴

17
- 77953372136
- O. Obianyo C. P. Causey T. C. Osborne J. E. Jones Y. H. Lee M. R. Stallcup P. R. Thompson ChemBioChem 2010 11 1219 1223
- (2010) ChemBioChem , vol.11 , pp. 1219-1223
- Obianyo, O.¹ Causey, C.P.² Osborne, T.C.³ Jones, J.E.⁴ Lee, Y.H.⁵ Stallcup, M.R.⁶ Thompson, P.R.⁷

18
- 78649684721
- T. M. Lakowski P. 't Hart C. A. Ahern N. I. Martin A. Frankel ACS Chem. Biol. 2010 5 1053 1063
- (2010) ACS Chem. Biol. , vol.5 , pp. 1053-1063
- Lakowski, T.M.¹ Hart, P.'.² Ahern, C.A.³ Martin, N.I.⁴ Frankel, A.⁵

19
- 79958713709
- P. 't Hart T. M. Lakowski D. Thomas A. Frankel N. I. Martin ChemBioChem 2011 12 1427 1432
- (2011) ChemBioChem , vol.12 , pp. 1427-1432
- Hart, P.'.¹ Lakowski, T.M.² Thomas, D.³ Frankel, A.⁴ Martin, N.I.⁵

20
- 2642551574
- D. Cheng N. Yadav R. W. King M. S. Swanson E. J. Weinstein M. T. Bedford J. Biol. Chem. 2004 279 23892 23899
- (2004) J. Biol. Chem. , vol.279 , pp. 23892-23899
- Cheng, D.¹ Yadav, N.² King, R.W.³ Swanson, M.S.⁴ Weinstein, E.J.⁵ Bedford, M.T.⁶

21
- 77955869789
- Y. Feng M. Y. Li B. H. Wang Y. G. Zheng J. Med. Chem. 2010 53 6028 6039
- (2010) J. Med. Chem. , vol.53 , pp. 6028-6039
- Feng, Y.¹ Li, M.Y.² Wang, B.H.³ Zheng, Y.G.⁴

22
- 77951237941
- K. Bonham S. Hemmers Y. H. Lim D. M. Hill M. G. Finn K. A. Mowen FEBS J. 2010 277 2096 2108
- (2010) FEBS J. , vol.277 , pp. 2096-2108
- Bonham, K.¹ Hemmers, S.² Lim, Y.H.³ Hill, D.M.⁴ Finn, M.G.⁵ Mowen, K.A.⁶

23
- 77249086700
- S. Castellano C. Milite R. Ragno S. Simeoni A. Mai V. Limongelli E. Novellino I. Bauer G. Brosch A. Spannhoff D. Cheng M. T. Bedford G. Sbardella ChemMedChem 2010 5 398 414
- (2010) ChemMedChem , vol.5 , pp. 398-414
- Castellano, S.¹ Milite, C.² Ragno, R.³ Simeoni, S.⁴ Mai, A.⁵ Limongelli, V.⁶ Novellino, E.⁷ Bauer, I.⁸ Brosch, G.⁹ Spannhoff, A.¹⁰ Cheng, D.¹¹ Bedford, M.T.¹² Sbardella, G.¹³

24
- 33947685838
- R. Ragno S. Simeoni S. Castellano C. Vicidomini A. Mai A. Caroli A. Tramontano C. Bonaccini P. Trojer I. Bauer G. Brosch G. Sbardella J. Med. Chem. 2007 50 1241 1253
- (2007) J. Med. Chem. , vol.50 , pp. 1241-1253
- Ragno, R.¹ Simeoni, S.² Castellano, S.³ Vicidomini, C.⁴ Mai, A.⁵ Caroli, A.⁶ Tramontano, A.⁷ Bonaccini, C.⁸ Trojer, P.⁹ Bauer, I.¹⁰ Brosch, G.¹¹ Sbardella, G.¹²

25
- 47849115661
- A. V. Purandare Z. Chen T. Huynh S. Pang J. Geng W. Vaccaro M. A. Poss J. O'Connell K. Nowak L. Jayaraman Bioorg. Med. Chem. Lett. 2008 18 4438 4441
- (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 4438-4441
- Purandare, A.V.¹ Chen, Z.² Huynh, T.³ Pang, S.⁴ Geng, J.⁵ Vaccaro, W.⁶ Poss, M.A.⁷ O'Connell, J.⁸ Nowak, K.⁹ Jayaraman, L.¹⁰

26
- 59649090382
- M. Allan S. Manku E. Therrien N. Nguyen S. Styhler M. F. Robert A. C. Goulet A. J. Petschner G. Rahil A. Robert Macleod R. Déziel J. M. Besterman H. Nguyen A. Wahhab Bioorg. Med. Chem. Lett. 2009 19 1218 1223
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 1218-1223
- Allan, M.¹ Manku, S.² Therrien, E.³ Nguyen, N.⁴ Styhler, S.⁵ Robert, M.F.⁶ Goulet, A.C.⁷ Petschner, A.J.⁸ Rahil, G.⁹ MacLeod, A.R.¹⁰ Déziel, R.¹¹ Besterman, J.M.¹² Nguyen, H.¹³ Wahhab, A.¹⁴

27
- 65549130422
- T. Huynh Z. Chen S. Pang J. Geng T. Bandiera S. Bindi P. Vianello F. Roletto S. Thieffine A. Galvani W. Vaccaro M. A. Poss G. L. Trainor M. V. Lorenzi M. Gottardis L. Jayaraman A. V. Purandare Bioorg. Med. Chem. Lett. 2009 19 2924 2927
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 2924-2927
- Huynh, T.¹ Chen, Z.² Pang, S.³ Geng, J.⁴ Bandiera, T.⁵ Bindi, S.⁶ Vianello, P.⁷ Roletto, F.⁸ Thieffine, S.⁹ Galvani, A.¹⁰ Vaccaro, W.¹¹ Poss, M.A.¹² Trainor, G.L.¹³ Lorenzi, M.V.¹⁴ Gottardis, M.¹⁵ Jayaraman, L.¹⁶ Purandare, A.V.¹⁷

28
- 68449090273
- H. Wan T. Huynh S. Pang J. Geng W. Vaccaro M. A. Poss G. L. Trainor M. V. Lorenzi M. Gottardis L. Jayaraman A. V. Purandare Bioorg. Med. Chem. Lett. 2009 19 5063 5066
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 5063-5066
- Wan, H.¹ Huynh, T.² Pang, S.³ Geng, J.⁴ Vaccaro, W.⁵ Poss, M.A.⁶ Trainor, G.L.⁷ Lorenzi, M.V.⁸ Gottardis, M.⁹ Jayaraman, L.¹⁰ Purandare, A.V.¹¹

29
- 71749083438
- E. Therrien G. Larouche S. Manku M. Allan N. Nguyen S. Styhler M. F. Robert A. C. Goulet J. M. Besterman H. Nguyen A. Wahhab Bioorg. Med. Chem. Lett. 2009 19 6725 6732
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 6725-6732
- Therrien, E.¹ Larouche, G.² Manku, S.³ Allan, M.⁴ Nguyen, N.⁵ Styhler, S.⁶ Robert, M.F.⁷ Goulet, A.C.⁸ Besterman, J.M.⁹ Nguyen, H.¹⁰ Wahhab, A.¹¹

30
- 79956042756
- J. S. Sack S. Thieffine T. Bandiera M. Fasolini G. J. Duke L. Jayaraman K. F. Kish H. E. Klei A. V. Purandare P. Rosettani S. Troiani D. Xie J. A. Bertrand Biochem. J. 2011 436 331 339
- (2011) Biochem. J. , vol.436 , pp. 331-339
- Sack, J.S.¹ Thieffine, S.² Bandiera, T.³ Fasolini, M.⁴ Duke, G.J.⁵ Jayaraman, L.⁶ Kish, K.F.⁷ Klei, H.E.⁸ Purandare, A.V.⁹ Rosettani, P.¹⁰ Troiani, S.¹¹ Xie, D.¹² Bertrand, J.A.¹³

31
- 77949491799
- J. Dowden W. Hong R. V. Parry R. A. Pike S. G. Ward Bioorg. Med. Chem. Lett. 2010 20 2103 2105
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 2103-2105
- Dowden, J.¹ Hong, W.² Parry, R.V.³ Pike, R.A.⁴ Ward, S.G.⁵

32
- 79953187310
- V. Campagna-Slater M. W. Mok K. T. Nguyen M. Feher R. Najmanovich M. Schapira J. Chem. Inf. Model. 2011 51 612 623
- (2011) J. Chem. Inf. Model. , vol.51 , pp. 612-623
- Campagna-Slater, V.¹ Mok, M.W.² Nguyen, K.T.³ Feher, M.⁴ Najmanovich, R.⁵ Schapira, M.⁶

33
- 0032564592
- A. M. Reeve C. A. Townsend Tetrahedron 1998 54 15959 15974
- (1998) Tetrahedron , vol.54 , pp. 15959-15974
- Reeve, A.M.¹ Townsend, C.A.²

34
- 0001034362
- R. M. Werner O. Shokek J. T. Davis J. Org. Chem. 1997 62 8243 8246
- (1997) J. Org. Chem. , vol.62 , pp. 8243-8246
- Werner, R.M.¹ Shokek, O.² Davis, J.T.³

35
- 0023144723
- M. Kolb J. Barth J.-G. Heydt M. J. Jung J. Med. Chem. 1987 30 267 272
- (1987) J. Med. Chem. , vol.30 , pp. 267-272
- Kolb, M.¹ Barth, J.² Heydt, J.-G.³ Jung, M.J.⁴

36
- 16444385635
- S. Hourcade A. Ferdenzi P. Retailleau S. Mons C. Marazano Eur. J. Org. Chem. 2005 1302 1310
- (2005) Eur. J. Org. Chem. , pp. 1302-1310
- Hourcade, S.¹ Ferdenzi, A.² Retailleau, P.³ Mons, S.⁴ Marazano, C.⁵

37
- 79955564633
- N. S. Freeman,Y. Tal-Gan S. Klein A. Levitzki C. Gilon J. Org. Chem. 2011 76 3078 3085
- (2011) J. Org. Chem. , vol.76 , pp. 3078-3085
- Tal-Gan, N.S.¹ Freeman, Y.² Klein, S.³ Levitzki, A.⁴ Gilon, C.⁵

38
- 78249255193
- S. Mori K. Iwase N. Iwanami Y. Tanaka H. Kagechika T. Hirano Bioorg. Med. Chem. 2010 18 8158 8166
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 8158-8166
- Mori, S.¹ Iwase, K.² Iwanami, N.³ Tanaka, Y.⁴ Kagechika, H.⁵ Hirano, T.⁶

39
- 0037904754
- X. Zhang X. D. Cheng Structure 2003 11 509 520
- (2003) Structure , vol.11 , pp. 509-520
- Zhang, X.¹ Cheng, X.D.²

40
- 76149120388
- O. Trott A. J. Olson J. Comput. Chem. 2010 31 455 461
- (2010) J. Comput. Chem. , vol.31 , pp. 455-461
- Trott, O.¹ Olson, A.J.²

41
- 77749264270
- L. K. Wolf Chem. Eng. News 2009 87 31
- (2009) Chem. Eng. News , vol.87 , pp. 31
- Wolf, L.K.¹

42
- 79955079071
- H. L. Rust C. I. Zurita-Lopez S. Clarke P. R. Thompson Biochemistry 2011 50 3332 3345
- (2011) Biochemistry , vol.50 , pp. 3332-3345
- Rust, H.L.¹ Zurita-Lopez, C.I.² Clarke, S.³ Thompson, P.R.⁴

43
- 0034679591
- X. Zhang L. Zhou X. D. Cheng EMBO J. 2000 19 3509 3519
- (2000) EMBO J. , vol.19 , pp. 3509-3519
- Zhang, X.¹ Zhou, L.² Cheng, X.D.³

44
- 35348916034
- N. Troffer-Charlier V. Cura P Hassenboehler D. Moras J. Cavarelli EMBO J. 2007 26 4391 4401
- (2007) EMBO J. , vol.26 , pp. 4391-4401
- Troffer-Charlier, N.¹ Cura, V.² Hassenboehler, P.³ Moras, D.⁴ Cavarelli, J.⁵

45
- 33745359822
- The Open Babel Package, version 2.3.0 (accessed Jan 2011)
- R. Guha M. T. Howard G. R. Hutchison P. Murray-Rust H. Rzepa C. Steinbeck J. K. Wegner E. Willighagen J. Chem. Inf. Model. 2006 46 991 998
- (2006) J. Chem. Inf. Model. , vol.46 , pp. 991-998
- Guha, R.¹ Howard, M.T.² Hutchison, G.R.³ Murray-Rust, P.⁴ Rzepa, H.⁵ Steinbeck, C.⁶ Wegner, J.K.⁷ Willighagen, E.⁸

46
- 0003845223
- DeLano Scientific LLC, Palo Alto, CA, USA
- W. L. DeLano The PyMOL Molecular Graphics System. (2008) DeLano Scientific LLC, Palo Alto, CA, USA
- (2008) The PyMOL Molecular Graphics System
- Delano, W.L.¹

47
- 33847142225
- M. Petrek M. Otyepka P. Banás P. Kosinová J. Koca J. Damborský BMC Bioinformatics 2006 7 316
- (2006) BMC Bioinformatics , vol.7 , pp. 316
- Petrek, M.¹ Otyepka, M.² Banás, P.³ Kosinová, P.⁴ Koca, J.⁵ Damborský, J.⁶

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