-
1
-
-
23944491920
-
HIV protease inhibitors activate the unfolded protein response in macrophages: Implication for atherosclerosis and cardiovascular disease
-
DOI 10.1124/mol.105.012898
-
H. Zhou, W.M. Pandak, V. Lyall Jr. , R. Natarajan, and P.B. Hylemon HIV protease inhibitors activate the unfolded protein response in macrophages: implication for atherosclerosis and cardiovascular disease Mol. Pharmacol. 68 3 2005 690 700 (Pubitemid 41206022)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.3
, pp. 690-700
-
-
Zhou, H.1
Pandak Jr., W.M.2
Lyall, V.3
Natarajan, R.4
Hylemon, P.B.5
-
2
-
-
33644969260
-
Estrogen receptor-alpha mediates gender differences in atherosclerosis induced by HIV protease inhibitors
-
K.F. Allred, E.J. Smart, and M.E. Wilson Estrogen receptor-alpha mediates gender differences in atherosclerosis induced by HIV protease inhibitors J. Biol. Chem. 281 3 2006 1419 1425
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.3
, pp. 1419-1425
-
-
Allred, K.F.1
Smart, E.J.2
Wilson, M.E.3
-
3
-
-
73649112372
-
The soybean isoflavonoid equol blocks ritonavir-induced endothelial dysfunction in porcine pulmonary arteries and human pulmonary artery endothelial cells
-
C. Cheng, X. Wang, S.M. Weakley, P. Kougias, P.H. Lin, Q. Yao, and C. Chen The soybean isoflavonoid equol blocks ritonavir-induced endothelial dysfunction in porcine pulmonary arteries and human pulmonary artery endothelial cells J. Nutr. 140 2010 12 17
-
(2010)
J. Nutr.
, vol.140
, pp. 12-17
-
-
Cheng, C.1
Wang, X.2
Weakley, S.M.3
Kougias, P.4
Lin, P.H.5
Yao, Q.6
Chen, C.7
-
4
-
-
0037072879
-
Macrophage foam cell formation with native low density lipoprotein
-
H.S. Kruth, W. Huang, I. Ishii, and W.Y. Zhang Macrophage foam cell formation with native low density lipoprotein J. Biol. Chem. 277 37 2002 34573 34580
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.37
, pp. 34573-34580
-
-
Kruth, H.S.1
Huang, W.2
Ishii, I.3
Zhang, W.Y.4
-
5
-
-
9644264080
-
Involvement of PKCα/β in TLR4 and TLR2 dependent activation of NF-κB
-
DOI 10.1016/j.cellsig.2004.08.005, PII S0898656804001639
-
K. Asehnoune, D. Strassheim, S. Mitra, J. Yeol Kim, and E. Abraham Involvement of PKC alpha/beta in TLR4 and TLR2 dependent activation of NF-kappaB Cell Signal. 17 3 2005 385 394 (Pubitemid 39574699)
-
(2005)
Cellular Signalling
, vol.17
, Issue.3
, pp. 385-394
-
-
Asehnoune, K.1
Strassheim, D.2
Mitra, S.3
Kim, J.Y.4
Abraham, E.5
-
6
-
-
0027375416
-
Protein kinase C activation in human monocytes: Regulation of PKC isoforms
-
Z.L. Chang, and D.H. Beezhold Protein kinase C activation in human monocytes: regulation of PKC isoforms Immunology 80 3 1993 360 366 (Pubitemid 23336683)
-
(1993)
Immunology
, vol.80
, Issue.3
, pp. 360-366
-
-
Chang, Z.-L.1
Beezhold, D.H.2
-
7
-
-
61749097572
-
PKCα regulates platelet granule secretion and thrombus formation in mice
-
O. Konopatskaya, K. Gilio, M.T. Harper, Y. Zhao, J.M. Cosemans, Z.A. Karim, S.W. Whiteheart, J.D. Molkentin, P. Verkade, S.P. Watson, J.W.M. Heemskerk, and A.W. Poole PKCα regulates platelet granule secretion and thrombus formation in mice J. Clin. Invest. 119 2 2009 399 407
-
(2009)
J. Clin. Invest.
, vol.119
, Issue.2
, pp. 399-407
-
-
Konopatskaya, O.1
Gilio, K.2
Harper, M.T.3
Zhao, Y.4
Cosemans, J.M.5
Karim, Z.A.6
Whiteheart, S.W.7
Molkentin, J.D.8
Verkade, P.9
Watson, S.P.10
Heemskerk, J.W.M.11
Poole, A.W.12
-
8
-
-
33845331366
-
Nucleoside reverse transcriptase inhibitors prevent HIV protease inhibitor-induced atherosclerosis by ubiquitination and degradation of protein kinase C
-
E.L. Bradshaw, X.A. Li, T. Guerin, W.V. Everson, M.E. Wilson, A.J. Bruce-Keller, R.N. Greenberg, L. Guo, S.A. Ross, and E.J. Smart Nucleoside reverse transcriptase inhibitors prevent HIV protease inhibitor-induced atherosclerosis by ubiquitination and degradation of protein kinase C Am. J. Physiol. Cell Physiol. 291 6 2006 C1271 1278
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.291
, Issue.6
, pp. 1271-1278
-
-
Bradshaw, E.L.1
Li, X.A.2
Guerin, T.3
Everson, W.V.4
Wilson, M.E.5
Bruce-Keller, A.J.6
Greenberg, R.N.7
Guo, L.8
Ross, S.A.9
Smart, E.J.10
-
9
-
-
0037312029
-
HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages
-
DOI 10.1172/JCI200316261
-
J. Dressman, J. Kincer, S.V. Matveev, L. Guo, R.N. Greenberg, T. Guerin, D. Meade, X.A. Li, W. Zhu, A. Uittenbogaard, M.E. Wilson, and E.J. Smart HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages J. Clin. Invest. 111 3 2003 389 397 (Pubitemid 36182216)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.3
, pp. 389-397
-
-
Dressman, J.1
Kincer, J.2
Matveev, S.V.3
Guo, L.4
Greenberg, R.N.5
Guerin, T.6
Meade, D.7
Li, X.-A.8
Zhu, W.9
Uittenbogaard, A.10
Wilson, M.E.11
Smart, E.J.12
-
10
-
-
58749109659
-
Ritonavir increases CD36, ABCA1 and CYP27 expression in THP-1 macrophages
-
J. Pou, A. Rebollo, N. Roglans, R.M. Sanchez, M. Vazquez-Carrera, J.C. Laguna, J. Pedro-Botet, and M. Alegret Ritonavir increases CD36, ABCA1 and CYP27 expression in THP-1 macrophages Exp. Biol. Med. (Maywood) 233 12 2008 1572 1582
-
(2008)
Exp. Biol. Med. (Maywood)
, vol.233
, Issue.12
, pp. 1572-1582
-
-
Pou, J.1
Rebollo, A.2
Roglans, N.3
Sanchez, R.M.4
Vazquez-Carrera, M.5
Laguna, J.C.6
Pedro-Botet, J.7
Alegret, M.8
-
11
-
-
0032498538
-
Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells
-
DOI 10.1083/jcb.140.3.485
-
E. Oancea, M.N. Teruel, A.F. Quest, and T. Meyer Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells J. Cell Biol. 140 3 1998 485 498 (Pubitemid 28134054)
-
(1998)
Journal of Cell Biology
, vol.140
, Issue.3
, pp. 485-498
-
-
Oancea, E.1
Teruel, M.N.2
Quest, A.F.G.3
Meyer, T.4
-
12
-
-
0031865214
-
Three distinct mechanisms for translocation and activation of the δ subspecies of protein kinase C
-
S. Ohmori, Y. Shirai, N. Sakai, M. Fujii, H. Konishi, U. Kikkawa, and N. Saito Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C Mol. Cell Biol. 18 9 1998 5263 5271 (Pubitemid 28388110)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.9
, pp. 5263-5271
-
-
Ohmori, S.1
Shirai, Y.2
Sakai, N.3
Fujii, M.4
Konishi, H.5
Kikkawa, U.6
Saito, N.7
-
13
-
-
0028922586
-
LIGPLOT: A program to generate schematic diagrams of protein-ligand interactions
-
A.C. Wallace, R.A. Laskowski, and J.M. Thornton LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions Protein Eng. 8 2 1995 127 134
-
(1995)
Protein Eng.
, vol.8
, Issue.2
, pp. 127-134
-
-
Wallace, A.C.1
Laskowski, R.A.2
Thornton, J.M.3
-
14
-
-
11644261806
-
Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
-
G.M. Morris, D.S. Goodsell, R.S. Halliday, R. Huey, W.E. Hart, R.K. Belew, and A.J. Olson Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function J. Comput. Chem. 19 14 1998 1639 1662 (Pubitemid 128590223)
-
(1998)
Journal of Computational Chemistry
, vol.19
, Issue.14
, pp. 1639-1662
-
-
Morris, G.M.1
Goodsell, D.S.2
Halliday, R.S.3
Huey, R.4
Hart, W.E.5
Belew, R.K.6
Olson, A.J.7
-
15
-
-
4644353680
-
Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease
-
DOI 10.1021/bi049459m
-
J.C. Clemente, R.E. Moose, R. Hemrajani, L.R. Whitford, L. Govindasamy, R. Reutzel, R. McKenna, M. Agbandje-McKenna, M.M. Goodenow, and B.M. Dunn Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease Biochemistry 43 38 2004 12141 12151 (Pubitemid 39280558)
-
(2004)
Biochemistry
, vol.43
, Issue.38
, pp. 12141-12151
-
-
Clemente, J.C.1
Moose, R.E.2
Hemrajani, R.3
Whitford, L.R.S.4
Govindasamy, L.5
Reutzel, R.6
McKenna, R.7
Agbandje-McKenna, M.8
Goodenow, M.M.9
Dunn, B.M.10
-
16
-
-
33846847536
-
Chlamydia pneumoniae-induced macrophage foam cell formation is mediated by toll-like receptor 2
-
DOI 10.1128/IAI.01386-06
-
F. Cao, A. Castrillo, P. Tontonoz, F. Re, and G.I. Byrne Chlamydia pneumoniae-induced macrophage foam cell formation is mediated by Toll-like receptor 2 Infect. Immun. 75 2 2007 753 759 (Pubitemid 46203437)
-
(2007)
Infection and Immunity
, vol.75
, Issue.2
, pp. 753-759
-
-
Cao, F.1
Castrillo, A.2
Tontonoz, P.3
Re, F.4
Byrne, G.I.5
-
17
-
-
35248838764
-
HIV protease inhibitors increase TNF-alpha and IL-6 expression in macrophages: Involvement of the RNA-binding protein HuR
-
H. Zhou, S. Jarujaron, E.C. Gurley, L. Chen, H. Ding, E. Studer, W.M. Pandak Jr. , W. Hu, T. Zou, J.Y. Wang, and P.B. Hylemon HIV protease inhibitors increase TNF-alpha and IL-6 expression in macrophages: involvement of the RNA-binding protein HuR Atherosclerosis 195 1 2007 e134 143
-
(2007)
Atherosclerosis
, vol.195
, Issue.1
, pp. 134-143
-
-
Zhou, H.1
Jarujaron, S.2
Gurley, E.C.3
Chen, L.4
Ding, H.5
Studer, E.6
Pandak Jr., W.M.7
Hu, W.8
Zou, T.9
Wang, J.Y.10
Hylemon, P.B.11
-
18
-
-
67349257146
-
HIV protease inhibitor lopinavir-induced TNF-alpha and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages
-
L. Chen, S. Jarujaron, X. Wu, L. Sun, W. Zha, G. Liang, X. Wang, E.C. Gurley, E.J. Studer, P.B. Hylemon, W.M. Pandak Jr. , L. Zhang, G. Wang, X. Li, P. Dent, and H. Zhou HIV protease inhibitor lopinavir-induced TNF-alpha and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages Biochem. Pharmacol. 78 1 2009 70 77
-
(2009)
Biochem. Pharmacol.
, vol.78
, Issue.1
, pp. 70-77
-
-
Chen, L.1
Jarujaron, S.2
Wu, X.3
Sun, L.4
Zha, W.5
Liang, G.6
Wang, X.7
Gurley, E.C.8
Studer, E.J.9
Hylemon, P.B.10
Pandak Jr., W.M.11
Zhang, L.12
Wang, G.13
Li, X.14
Dent, P.15
Zhou, H.16
-
19
-
-
77949366398
-
Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages
-
W. Zha, G. Liang, J. Xiao, E.J. Studer, P.B. Hylemon, W.M. Pandak Jr. , G. Wang, X. Li, and H. Zhou Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages PLoS One 5 2 2010 e9069
-
(2010)
PLoS One
, vol.5
, Issue.2
, pp. 9069
-
-
Zha, W.1
Liang, G.2
Xiao, J.3
Studer, E.J.4
Hylemon, P.B.5
Pandak Jr., W.M.6
Wang, G.7
Li, X.8
Zhou, H.9
-
20
-
-
61849179573
-
Targeting PKC: A novel role for beta-catenin in ER stress and apoptotic signaling
-
M.S. Raab, I. Breitkreutz, G. Tonon, J. Zhang, P.J. Hayden, T. Nguyen, J.H. Fruehauf, B.K. Lin, D. Chauhan, T. Hideshima, N.C. Munshi, K.C. Anderson, and K. Podar Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling Blood 113 7 2009 1513 1521
-
(2009)
Blood
, vol.113
, Issue.7
, pp. 1513-1521
-
-
Raab, M.S.1
Breitkreutz, I.2
Tonon, G.3
Zhang, J.4
Hayden, P.J.5
Nguyen, T.6
Fruehauf, J.H.7
Lin, B.K.8
Chauhan, D.9
Hideshima, T.10
Munshi, N.C.11
Anderson, K.C.12
Podar, K.13
-
21
-
-
33846186744
-
Protein kinase C zeta plays an essential role for Mycobacterium tuberculosis-induced extracellular signal-regulated kinase 1/2 activation in monocytes/macrophages via Toll-like receptor 2
-
DOI 10.1111/j.1462-5822.2006.00797.x
-
C.S. Yang, J.S. Lee, C.H. Song, G.M. Hur, S.J. Lee, S. Tanaka, S. Akira, T.H. Paik, and E.K. Jo Protein kinase C zeta plays an essential role for Mycobacterium tuberculosis-induced extracellular signal-regulated kinase 1/2 activation in monocytes/macrophages via Toll-like receptor 2 Cell Microbiol. 9 2 2007 382 396 (Pubitemid 46092167)
-
(2007)
Cellular Microbiology
, vol.9
, Issue.2
, pp. 382-396
-
-
Yang, C.-S.1
Lee, J.-S.2
Song, C.-H.3
Hur, G.M.4
Lee, S.J.5
Tanaka, S.6
Akira, S.7
Paik, T.-H.8
Jo, E.-K.9
-
22
-
-
0026741799
-
Reversible exposure of the pseudosubstrate domain of protein kinase C by phosphatidylserine and diacylglycerol
-
J.W. Orr, L.M. Keranen, and A.C. Newton Reversible exposure of the pseudosubstrate domain of protein kinase C by phosphatidylserine and diacylglycerol J. Biol. Chem. 267 22 1992 15263 15266
-
(1992)
J. Biol. Chem.
, vol.267
, Issue.22
, pp. 15263-15266
-
-
Orr, J.W.1
Keranen, L.M.2
Newton, A.C.3
-
23
-
-
0028843905
-
Mechanism of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane association
-
M. Mosior, and A.C. Newton Mechanism of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane association J. Biol. Chem. 270 43 1995 25526 25533
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.43
, pp. 25526-25533
-
-
Mosior, M.1
Newton, A.C.2
-
24
-
-
33845946450
-
Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms
-
DOI 10.1074/jbc.M606560200
-
Y. Pu, M.L. Peach, S.H. Garfield, S. Wincovitch, V.E. Marquez, and P.M. Blumberg Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms J. Biol. Chem. 281 44 2006 33773 33788 (Pubitemid 46036755)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.44
, pp. 33773-33788
-
-
Pu, Y.1
Peach, M.L.2
Garfield, S.H.3
Wincovitch, S.4
Marquez, V.E.5
Blumberg, P.M.6
-
25
-
-
2942534993
-
HIV protease inhibition: Limited recent progress and advances in understanding current pitfalls
-
DOI 10.2174/1568026043388529
-
F. Rodriguez-Barrios, and F. Gago HIV protease inhibition Limited recent progress and advances in understanding current pitfalls Curr. Top Med. Chem. 4 9 2004 991 1007 (Pubitemid 38854851)
-
(2004)
Current Topics in Medicinal Chemistry
, vol.4
, Issue.9
, pp. 991-1007
-
-
Rodriguez-Barrios, F.1
Gago, F.2
-
26
-
-
0023097509
-
A three-step purification procedure for protein kinase C: Characterization of the purified enzyme
-
DOI 10.1016/0003-2697(87)90471-4
-
G.M. Walton, P.J. Bertics, L.G. Hudson, T.S. Vedvick, and G.N. Gill A three-step purification procedure for protein kinase C: characterization of the purified enzyme Anal. Biochem. 161 2 1987 425 437 (Pubitemid 17045994)
-
(1987)
Analytical Biochemistry
, vol.161
, Issue.2
, pp. 425-437
-
-
Walton, G.M.1
Bertics, P.J.2
Hudson, L.G.3
-
27
-
-
5644271449
-
Protein kinase C alpha expression in breast and ovarian cancer
-
DOI 10.1159/000080279
-
M. Lahn, G. Kohler, K. Sundell, C. Su, S. Li, B.M. Paterson, and T.F. Bumol Protein kinase C alpha expression in breast and ovarian cancer Oncology 67 1 2004 1 10 (Pubitemid 39370344)
-
(2004)
Oncology
, vol.67
, Issue.1
, pp. 1-10
-
-
Lahn, M.1
Kohler, G.2
Sundell, K.3
Su, C.4
Li, S.5
Paterson, B.M.6
Bumol, T.F.7
-
28
-
-
0031857385
-
Effect of ritonavir on the pharmacokinetics of ethinyl oestradiol in healthy female volunteers
-
DOI 10.1046/j.1365-2125.1998.00749.x
-
D. Ouellet, A. Hsu, J. Qian, C.S. Locke, C.J. Eason, J.H. Cavanaugh, J.M. Leonard, and G.R. Granneman Effect of ritonavir on the pharmacokinetics of ethinyl oestradiol in healthy female volunteers Br. J. Clin. Pharmacol. 46 2 1998 111 116 (Pubitemid 28342780)
-
(1998)
British Journal of Clinical Pharmacology
, vol.46
, Issue.2
, pp. 111-116
-
-
Ouellet, D.1
Hsu, A.2
Qian, J.3
Locke, C.S.4
Eason, C.J.5
Cavanaugh, J.H.6
Leonard, J.M.7
Granneman, G.R.8
-
29
-
-
62549085553
-
Roles and mechanisms of human immunodeficiency virus protease inhibitor ritonavir and other anti-human immunodeficiency virus drugs in endothelial dysfunction of porcine pulmonary arteries and human pulmonary artery endothelial cells
-
X. Wang, H. Chai, P.H. Lin, Q. Yao, and C. Chen Roles and mechanisms of human immunodeficiency virus protease inhibitor ritonavir and other anti-human immunodeficiency virus drugs in endothelial dysfunction of porcine pulmonary arteries and human pulmonary artery endothelial cells Am. J. Pathol. 174 3 2009 771 781
-
(2009)
Am. J. Pathol.
, vol.174
, Issue.3
, pp. 771-781
-
-
Wang, X.1
Chai, H.2
Lin, P.H.3
Yao, Q.4
Chen, C.5
-
30
-
-
0032317247
-
Analysis of ritonavir in plasma/serum and tissues by high-performance liquid chromatography
-
DOI 10.1016/S1056-8719(99)00013-1, PII S1056871999000131
-
B.W. Granda, G.M. Giancarlo, L.L. von Moltke, and D.J. Greenblatt Analysis of ritonavir in plasma/serum and tissues by high-performance liquid chromatography J. Pharmacol. Toxicol. Methods 40 4 1998 235 239 (Pubitemid 29356133)
-
(1998)
Journal of Pharmacological and Toxicological Methods
, vol.40
, Issue.4
, pp. 235-239
-
-
Granda, B.W.1
Giancarlo, G.M.2
Von Moltke, L.L.3
Greenblatt, D.J.4
-
31
-
-
43449105323
-
Liver lipid metabolism
-
DOI 10.1111/j.1439-0396.2007.00752.x
-
P. Nguyen, V. Leray, M. Diez, S. Serisier, J. Le Bloc'h, B. Siliart, and H. Dumon Liver lipid metabolism J. Anim. Physiol. Anim. Nutr. (Berl) 92 3 2008 272 283 (Pubitemid 351670169)
-
(2008)
Journal of Animal Physiology and Animal Nutrition
, vol.92
, Issue.3
, pp. 272-283
-
-
Nguyen, P.1
Leray, V.2
Diez, M.3
Serisier, S.4
Le Bloc'H, J.5
Siliart, B.6
Dumon, H.7
|