Clinical and prognostic features among children with acute encephalitis syndrome in Nepal; a retrospective study

BMC Infectious Diseases

Volumn 11, Issue , 2011, Pages

  Rayamajhi, Ajit ^a,b,c   Ansari, Imran ^b,d   Ledger, Elizabeth ^c   Bista, Krishna P ^a   Impoinvil, Daniel E ^c   Nightingale, Sam ^c   BC, Rajendra K ^e   Mahaseth, Chandeshwor ^a,b   Solomon, Tom ^c   Griffiths, Michael J ^c  

^a Kanti Children's Hospital   (Nepal)

^b National Academy of Medical Sciences   (Nepal)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d PATAN HOSPITAL   (Nepal)

^e Norway   (Nepal)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; IMMUNOGLOBULIN M ANTIBODY; MANNITOL; PHENOBARBITAL; PHENYTOIN; IMMUNOGLOBULIN M; VIRUS ANTIBODY;

ACUTE ENCEPHALITIS SYNDROME; ADOLESCENT; ANTIBODY BLOOD LEVEL; ANTIBODY CEREBROSPINAL FLUID LEVEL; ARTICLE; BACTERIAL INFECTION; BREATHING RATE; CEREBROSPINAL FLUID LEVEL; CHILD; CLINICAL FEATURE; CONSCIOUSNESS DISORDER; CONTROLLED STUDY; DEATH; DISEASE CLASSIFICATION; DISEASE DURATION; ENCEPHALITIS; FEMALE; FEVER; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; HUMAN CELL; LUMBAR PUNCTURE; MAJOR CLINICAL STUDY; MALE; NEPAL; NEUROLOGIC DISEASE; PARASITOSIS; PLASMODIUM INFECTION; PROGNOSIS; RETROSPECTIVE STUDY; VIRUS INFECTION; BACTERIUM; BLOOD; CEREBROSPINAL FLUID; HOSPITAL; INFANT; ISOLATION AND PURIFICATION; MORTALITY; PATHOLOGY; PLASMODIUM; PRESCHOOL CHILD; PUNCTURE; SURVIVAL; TREATMENT OUTCOME;

ADOLESCENT; ANTIBODIES, VIRAL; BACTERIA; CHILD; CHILD, PRESCHOOL; ENCEPHALITIS; FEMALE; HOSPITALS; HUMANS; IMMUNOGLOBULIN M; INFANT; MALE; NEPAL; NERVOUS SYSTEM DISEASES; PLASMODIUM; PROGNOSIS; RETROSPECTIVE STUDIES; SPINAL PUNCTURE; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 80054998440     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-11-294     Document Type: Article

References (22)

1. Solomon T, Thao TT, Lewthwaite P, Ooi MH, Kneen R, Dung NM, White N. A cohort study to assess the new WHO Japanese encephalitis surveillance standards. Bull World Health Organ 2008, 86(3):178-186. 10.2471/BLT.07.043307, 2647413, 18368204.
2. Granerod J, Crowcroft NS. The epidemiology of acute encephalitis. Neuropsychol Rehabil 2007, 17(4-5):406-428. 10.1080/09602010600989620, 17676528.
3. Rayamajhi A, Singh R, Prasad R, Khanal B, Singhi S. Study of Japanese encephalitis and other viral encephalitis in Nepali children. Pediatr Int 2007, 49(6):978-984. 10.1111/j.1442-200X.2007.02495.x, 18045307.
4. Rayamajhi A, Singh R, Prasad R, Khanal B, Singhi S. Clinico-laboratory profile and outcome of Japanese encephalitis in Nepali children. Ann Trop Paediatr 2006, 26(4):293-301. 10.1179/146532806X152818, 17132294.
5. Solomon T, Dung NM, Kneen R, Thao le TT, Gainsborough M, Nisalak A, Day NP, Kirkham FJ, Vaughn DW, Smith S, et al. Seizures and raised intracranial pressure in Vietnamese patients with Japanese encephalitis. Brain 2002, 125(Pt 5):1084-1093.
6. Solomon T, Dung NM, Wills B, Kneen R, Gainsborough M, Diet TV, Thuy TT, Loan HT, Khanh VC, Vaughn DW, et al. Interferon alfa-2a in Japanese encephalitis: a randomised double-blind placebo-controlled trial. Lancet 2003, 361(9360):821-826. 10.1016/S0140-6736(03)12709-2, 12642049.
7. Pant GR. A serological survey of pigs, horses, and ducks in Nepal for evidence of infection with Japanese encephalitis virus. Ann N Y Acad Sci 2006, 1081:124-129. 10.1196/annals.1373.013, 17135501.
8. Solomon T, Dung NM, Kneen R, Gainsborough M, Vaughn DW, Khanh VT. Japanese encephalitis. J Neurol Neurosurg Psychiatry 2000, 68(4):405-415. 10.1136/jnnp.68.4.405, 1736874, 10727474.
9. Libraty DH, Nisalak A, Endy TP, Suntayakorn S, Vaughn DW, Innis BL. Clinical and immunological risk factors for severe disease in Japanese encephalitis. Trans R Soc Trop Med Hyg 2002, 96(2):173-178. 10.1016/S0035-9203(02)90294-4, 12055808.
10. Kumar R, Mathur A, Kumar A, Sharma S, Chakraborty S, Chaturvedi UC. Clinical features & prognostic indicators of Japanese encephalitis in children in Lucknow (India). Indian J Med Res 1990, 91:321-327.
11. Berkley JA, Mwangi I, Ngetsa CJ, Mwarumba S, Lowe BS, Marsh K, Newton CR. Diagnosis of acute bacterial meningitis in children at a district hospital in sub-Saharan Africa. Lancet 2001, 357(9270):1753-1757. 10.1016/S0140-6736(00)04897-2, 11403812.
12. Innis BL, Nisalak A, Nimmannitya S, Kusalerdchariya S, Chongswasdi V, Suntayakorn S, Puttisri P, Hoke CH. An enzyme-linked immunosorbent assay to characterize dengue infections where dengue and Japanese encephalitis co-circulate. Am J Trop Med Hyg 1989, 40(4):418-427.
13. Behrman REKR, Jenson HB. Nelson Textbook of Paediatrics. 2004, Philadelphia: Saunders, 17.
14. Solomon T, Koelemay K, Marfin A, Roth C, Jacobson J, Ooi MH, Rao N, Sabchareon A, Namghyal P, Hills S, et al. Guidelines for management of children presenting with symptoms or signs of acute encephalitis syndrome. Japanese Encephalitis Clinical Care Guidelines 2005, PATH.
15. Tiroumourougane SV, Raghava P, Srinivasana S, Badrinath. Management parameters affecting the outcome of Japanese encephalitis. J Trop Pediatr 2003, 49(3):153-156. 10.1093/tropej/49.3.153, 12848204.
16. Clifton GL, Miller ER, Choi SC, Levin HS. Fluid thresholds and outcome from severe brain injury. Crit Care Med 2002, 30(4):739-745. 10.1097/00003246-200204000-00003, 11940738.
17. Gwer S, Gatakaa H, Mwai L, Idro R, Newton CR. The role for osmotic agents in children with acute encephalopathies: a systematic review. BMC Pediatr 2010, 10:23. 10.1186/1471-2431-10-23, 2859077, 20398408.
18. Klein SK, Hom DL, Anderson MR, Latrizza AT, Toltzis P. Predictive factors of short-term neurologic outcome in children with encephalitis. Pediatr Neurol 1994, 11(4):308-312. 10.1016/0887-8994(94)90007-8, 7702691.
19. Dung NM, Turtle L, Chong WK, Mai NT, Thao TT, Thuy TT, Kneen R, Phu NH, Wills B, Farrar J, et al. An evaluation of the usefulness of neuroimaging for the diagnosis of Japanese encephalitis. J Neurol 2009,
20. Namutangula B, Ndeezi G, Byarugaba JS, Tumwine JK. Mannitol as adjunct therapy for childhood cerebral malaria in Uganda: a randomized clinical trial. Malar J 2007, 6:138. 10.1186/1475-2875-6-138, 2147028, 17958887.
21. Kumar G, Kalita J, Misra UK. Raised intracranial pressure in acute viral encephalitis. Clin Neurol Neurosurg 2009, 111(5):399-406. 10.1016/j.clineuro.2009.03.004, 19372001.
22. Blackman JA, Patrick PD, Buck ML, Rust RS. Paroxysmal autonomic instability with dystonia after brain injury. Arch Neurol 2004, 61(3):321-328. 10.1001/archneur.61.3.321, 15023807.