An anti-transferrin receptor antibody enhanced the growth inhibitory effects of chemotherapeutic drugs on human glioma cells

International Immunopharmacology

Volumn 11, Issue 11, 2011, Pages 1844-1849

  Xu, Guozheng ^a   Wen, Xue ^a   Hong, Yi ^b,c   Du, Hao ^a   Zhang, Xinyuan ^a   Song, Jian ^a   Yin, Yimei ^a   Huang, He ^a   Shen, Guanxin ^b  

^a WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c HUBEI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Chemoimmunotherapy; Glioma; Monoclonal antibody; Nimustine; Transferrin receptor

Indexed keywords

7579 MONOCLONAL ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; LIPOCORTIN 5; MONOCLONAL ANTIBODY; NIMUSTINE; PROPIDIUM IODIDE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL DEATH; CELL PROLIFERATION; CYTOTOXICITY; DOWN REGULATION; DRUG POTENTIATION; FLOW CYTOMETRY; GLIOBLASTOMA; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SYNERGISM; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; NIMUSTINE; RECEPTORS, TRANSFERRIN;

EID: 80054996338     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.07.014     Document Type: Article

References (31)

1. P. Kleihues, D.N. Louis, B.W. Scheithauer, L.B. Rorke, G. Reifenberger, and P.C. Burger The WHO classification of tumors of the nervous system J Neuropathol Exp Neurol 61 2002 215 225 (Pubitemid 34212595)
2. A.A. Brandes State-of-the-art treatment of high-grade brain tumors Semin Oncol 30 2003 4 9 (Pubitemid 38199156)
3. M.D. Prados, and V. Levin Biology and treatment of malignant glioma Semin Oncol 27 2000 1 10 (Pubitemid 30390229)
4. D.T. Jone, I.S. Trowbridge, and A.L. Harris Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate Cancer Res 66 2006 2749 2756
5. J.L. Peng, S. Wu, X.P. Zhao, M. Wang, W.H. Li, and X. Shen Downregulation of transferrin receptor surface expression by intracellular antibody Biochem Biophys Res Commun 354 2007 864 871 (Pubitemid 46216213)
6. P.P. Ng, J.S. Dela Cruz, D.N. Sorour, J.M. Stinebaugh, S.U. Shin, and D.S. Shin An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells Proc Natl Acad Sci USA 99 2002 10706 10711
7. I.S. Trowbridge, and D.L. Domingo Anti-transferrin receptor monoclonal antibody and toxinantibody conjugates affect growth of human tumor cells Nature 294 1981 171 173 (Pubitemid 12217978)
8. D.L. Domingo, and I.S. Trowbridge Transferrin receptor as a target for antibody-drug conjugates Methods Enzymol 112 1985 238 247 (Pubitemid 15036585)
9. K. Okamoto, K. Harada, S. Ikeyama, and S. Iwasa Therapeutic effect of ansamitocin targeted to tumor by a bispecific monoclonal antibody Jpn J Cancer Res 83 7 1992 761 768
10. I. Graziadei, S. Gaggl, R. Kaserbacher, H. Braunsteiner, and W. Vogel The acute-phase protein alpha 1-antitrypsin inhibits growth and proliferation of human early erythroid progenitor cells (burst-forming units-erythroid) and of human erythroleukemic cells (K562) in vitro by interfering with transferrin iron uptake Blood 83 1 1994 260 268
11. S.M. Chan, P.B. Hoffer, N. Maric, and P. Duray Inhibition of gallium-67 uptake in melanoma by an anti-human transferrin receptor monoclonal antibody J Nucl Med 28 8 1987 1303 1307 (Pubitemid 17156418)
12. D. Brooks, C. Taylor, B. Dos Santos, H. Linden, A. Houghton, and T.T. Hecht Phase Ia trial of murine immunoglobulin an antitransferrin receptor antibody 42/6 Clin Cancer Res 11 1995 1259 1265
13. I.C. Moura, Y. Lepelletier, B. Arnulf, P. England, C. Baude, and C. Beaumont A neutralizing monoclonal antibody (mAb/A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients Blood 103 2004 1838 1845 (Pubitemid 38268981)
14. Y. Lepelletier, V. Camara-Clayette, H. Jin, A. Hermant, S. Coulon, and M. Dussiot Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments Cancer Res 67 2007 1145 1154
15. P.P. Ng, G. Helguera, T.R. Daniels, S.Z. Lomas, J.A. Rodriguez, and G. Schiller Molecularevents contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor Blood 108 2006 2745 2754
16. K. Kondo, M. Noguchi, K. Mukai, Y. Matsuno, Y. Sato, and Y. Shimosato Transferrin receptor expression in adenocarcinoma of the lung as a histopathologic indicator of prognosis Chest 97 1990 1367 1371 (Pubitemid 20185681)
17. G.J. Seymour, M.D. Walsh, M.F. Lavin, G. Strutton, and R.A. Gardiner Transferrin receptor expression by human bladder transitional cell carcinomas Urol Res 15 1987 341 344
18. D.C. Yang, F. Wang, R.L. Elliott, and J.F. Head Expression of transferrin receptor and ferritin H-chain mRNA are associated with clinical and histopathological prognostic indicators in breast cancer Anti-cancer Res 21 2001 541 549 (Pubitemid 32267568)
19. E. Ryschich, G. Huszty, H.P. Knaebel, M. Hartel, M.W. Buchler, and J. Schmidt Transferrin receptor is a marker of malignant phenotype in human pancreatic cancer and in neuroendocrine carcinoma of the pancreas Eur J Cancer 40 2004 1418 1422 (Pubitemid 38737029)
20. H.S. Gwak, S.M. Youn, A.H. Kwon, S.H. Lee, J.H. Kim, and C.H. Rhee ACNU-cisplatin continuous infusion chemotherapy as salvage therapy for recurrent glioblastomas: phase II study J Neurooncol 75 2005 173 180 (Pubitemid 41819721)
21. Y. Qing, W. Shuo, W. Zhihua, Z. Huifen, L. Ping, and L. Lijiang The in vitro antitumor effect and in vivo tumor-specificity distribution of human-mouse chimeric antibody against transferrin receptor Cancer Immunol Immunother 55 2006 1111 1121 (Pubitemid 43800726)
22. Waander L. van Heerde, Saskia Robert-Offerman, Ewald Dumont, Leo Hofstra, Pieter A. Doevendans, and Jos F.M. Smits Markers of apoptosis in cardiovascular tissues: focus on Annexin V Cardiovasc Res 5 2000 549 559 (Pubitemid 30047121)
23. Y. Cheng, O. Zak, P. Aisen, S.C. Harrison, and T. Walz Structure of the human transferrin receptor-transferrin complex Cell 116 2004 565 576 (Pubitemid 38264433)
24. J.D. Kemp, J.A. Thorson, T.H. Mcalmont, M. Horowitz, J.S. Cowdery, and Z.K. Ballas Role of the transferring receptor in lymphocyte growth: a rat IgG monoclonal antibody against the murine transferrin receptor produces highly selective inhibition of T and B cell activation protocols J Immunol 138 1987 2422 2426 (Pubitemid 17051810)
25. I.S. Trowbridge, and F. Lopez Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cells growth in vitro Proc Natl Acad Sci USA 79 1982 1175 1179 (Pubitemid 12105570)
26. J.F. Lesley, and R.J. Schulte Inhibition of cell growth by monoclonal anti-transferrin receptor antibodies Mol Cell Biol 5 1985 1814 1821 (Pubitemid 15049138)
27. Y. Zhang, and W.M. Pardridge Rapid transferrin efflux from brain to blood across the blood-brain barrier J Neurochem 76 2001 1597 1600 (Pubitemid 32198265)
28. S. Skarlatos, T. Yoshikawa, and W.M. Pardridge Transport of [125I] transferrin through the rat blood-brain barrier in vivo Brain Res 683 1995 164 171
29. Hwa Jeong Lee, Ruben J. Boado, Dwaine A. Braasch, David R. Corey, M. William, and M.D. Pardridge Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington's disease with an antisense radiopharmaceutical and drug-targeting technology J Nucl Med 43 2002 948 956 (Pubitemid 34747821)
30. N. Shi, R.J. Boado, and W.M. Pardridge Antisense imaging of gene expression in the brain in vivo Proc Natl Acad Sci USA 97 2000 14709 14714 (Pubitemid 32016640)
31. H.J. Lee, B. Engelhardt, J. Lesley, U. Bickel, and W.M. Pardridge Targeting rat antimouse transferrin receptor monoclonal antibodies through the blood-brain barrier J Pharmacol Exp Ther 292 2000 1048 1052 (Pubitemid 30136600)