Effect of time to reperfusion on clinical outcome of anterior circulation strokes treated with thrombectomy: Pooled analysis of the MERCI and multi MERCI trials

Stroke

Volumn 42, Issue 11, 2011, Pages 3144-3149

  Nogueira, Raul G ^a   Smith, Wade S ^b   Sung, Gene ^c   Duckwiler, Gary ^d   Walker, Gary ^e   Roberts, Robin ^f   Saver, Jeffrey L ^g   Liebeskind, David S ^g  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Division of Clinical Research   (United States)

^f MCMASTER UNIVERSITY   (Canada)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

stroke outcomes; thrombectomy

Indexed keywords

GLUCOSE;

ADULT; AGE; AGED; ARTICLE; CEREBRAL REVASCULARIZATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INTERNAL CAROTID ARTERY OCCLUSION; MAJOR CLINICAL STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MORTALITY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PREDICTOR VARIABLE; PRIORITY JOURNAL; REPERFUSION; THROMBECTOMY; TIME; TIME TO REPERFUSION;

AGED; CEREBRAL REVASCULARIZATION; CEREBROVASCULAR CIRCULATION; COHORT STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REPERFUSION; STROKE; THROMBECTOMY; TIME FACTORS; TREATMENT OUTCOME;

EID: 80054996020     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.624163     Document Type: Article

References (18)

1. Liebeskind DS. Collateral circulation. Stroke. 2003;34:2279-2284. (Pubitemid 37099848)
2. Saver JL. Time is brain-quantified. Stroke. 2006;37:263-266.
3. Marler JR, Tilley BC, Lu M, Brott TG, Lyden PC, Grotta JC, et al. Early stroke treatment associated with better outcome: The NINDS rt-PA stroke study. Neurology. 2000;55:1649-1655.
4. Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick JP, et al. Association of outcome with early stroke treatment: Pooled analysis of Atlantis, ECASS, and NINDS rt-PA stroke trials. Lancet. 2004;363: 768-774.
5. Hacke W, Kaste M, Bluhmki E, Brozman M, Davalos A, Guidetti D, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359:1317-1329.
6. Tsivgoulis G, Saqqur M, Sharma VK, Lao AY, Hill MD, Alexandrov AV, et al. Association of pretreatment blood pressure with tissue plasminogen activator-induced arterial recanalization in acute ischemic stroke. Stroke. 2007;38:961-966. (Pubitemid 46568459)
7. Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, et al. Time to treatment with intravenous alteplase and outcome in stroke: An updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010;375:1695-1703.
8. Smith WS, Sung G, Starkman S, Saver JL, Kidwell CS, Gobin YP, et al. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: Results of the MERCI trial. Stroke. 2005;36:1432-1438. (Pubitemid 40967507)
9. Smith WS, Sung G, Saver J, Budzik R, Duckwiler G, Liebeskind DS, et al. Mechanical thrombectomy for acute ischemic stroke: Final results of the Multi MERCI trial. Stroke. 2008;39:1205-1212. (Pubitemid 351440692)
10. Nogueira RG, Liebeskind DS, Sung G, Duckwiler G, Smith WS, MERCI, et al. Predictors of good clinical outcomes, mortality, and successful revascularization in patients with acute ischemic stroke undergoing thrombectomy: Pooled analysis of the mechanical embolus removal in cerebral ischemia (MERCI) and Multi MERCI trials. Stroke. 2009;40: 3777-3783.
11. Copen WA, Rezai Gharai L, Barak ER, Schwamm LH, Wu O, Kamalian S, et al. Existence of the diffusion-perfusion mismatch within 24 hours after onset of acute stroke: Dependence on proximal arterial occlusion. Radiology. 2009;250:878-886.
12. Khatri P, Abruzzo T, Yeatts SD, Nichols C, Broderick JP, Tomsick TA, et al. Good clinical outcome after ischemic stroke with successful revascularization is time-dependent. Neurology. 2009;73:1066-1072.
13. Kaur J, Zhao Z, Klein GM, Lo EH, Buchan AM. The neurotoxicity of tissue plasminogen activator? J Cereb Blood Flow Metab. 2004;24: 945-963. (Pubitemid 39223619)
14. Alvarez-Sabin J, Molina CA, Montaner J, Arenillas JF, Huertas R, Ribo M, et al. Effects of admission hyperglycemia on stroke outcome in reperfused tissue plasminogen activator-treated patients. Stroke. 2003;34: 1235-1241.
15. Martini SR, Kent TA. Hyperglycemia in acute ischemic stroke: A vascular perspective. J Cereb Blood Flow Metab. 2007;27:435-451.
16. Christoforidis GA, Mohammad Y, Kehagias D, Avutu B, Slivka AP. Angiographic assessment of pial collaterals as a prognostic indicator following intra-arterial thrombolysis for acute ischemic stroke. AJNR Am J Neuroradiol. 2005;26:1789-1797. (Pubitemid 43853681)
17. Hill MD, Rowley HA, Adler F, Eliasziw M, Furlan A, Higashida RT, et al. Selection of acute ischemic stroke patients for intra-arterial thrombolysis with pro-urokinase by using ASPECTS. Stroke. 2003;34: 1925-1931. (Pubitemid 36944782)
18. Tissue plasminogen activator for acute ischemic stroke. The national institute of neurological disorders and stroke rt-PA stroke study group. N Engl J Med. 1995;333:1581-1587.