-
1
-
-
79955509829
-
Cytomegalovirus: Pathogen, paradigm, and puzzle
-
Boeckh M, Geballe AP. Cytomegalovirus: pathogen, paradigm, and puzzle. J Clin Invest 2011; 121:1673-1689.
-
(2011)
J Clin Invest
, vol.121
, pp. 1673-1689
-
-
Boeckh, M.1
Geballe, A.P.2
-
2
-
-
77950926374
-
International consensus guidelines on the management of cytomegalovirus in solid organ transplantation
-
Kotton CN, Kumar D, Caliendo AM, et al. International consensus guidelines on the management of cytomegalovirus in solid organ transplantation. Transplantation 2010; 89:779-795.
-
(2010)
Transplantation
, vol.89
, pp. 779-795
-
-
Kotton, C.N.1
Kumar, D.2
Caliendo, A.M.3
-
3
-
-
78049355534
-
Antiviral drug resistance of human cytomegalovirus
-
Lurain NS, Chou S. Antiviral drug resistance of human cytomegalovirus. Clin Microbiol Rev 2010; 23:689-712.
-
(2010)
Clin Microbiol Rev
, vol.23
, pp. 689-712
-
-
Lurain, N.S.1
Chou, S.2
-
4
-
-
79955061244
-
The search for new therapies for human cytomegalovirus infections
-
Prichard MN, Kern ER. The search for new therapies for human cytomegalovirus infections. Virus Res 2011; 157:212-221.
-
(2011)
Virus Res
, vol.157
, pp. 212-221
-
-
Prichard, M.N.1
Kern, E.R.2
-
5
-
-
67650911368
-
Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir
-
Prichard MN. Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir. Rev Med Virol 2009; 19:215-229.
-
(2009)
Rev Med Virol
, vol.19
, pp. 215-229
-
-
Prichard, M.N.1
-
6
-
-
78149489550
-
Drug-resistant cytomegalovirus in transplant recipients: A French cohort study
-
Hantz S, Garnier-Geoffroy F, Mazeron MC, et al. Drug-resistant cytomegalovirus in transplant recipients: A French cohort study. J Antimicrob Chemother 2010; 65:2628-2640.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 2628-2640
-
-
Hantz, S.1
Garnier-Geoffroy, F.2
Mazeron, M.C.3
-
7
-
-
79960309676
-
Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients
-
Myhre HA, Haug Dorenberg D, Kristiansen KI, et al. Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients. Transplantation 2011; 92:217-223.
-
(2011)
Transplantation
, vol.92
, pp. 217-223
-
-
Myhre, H.A.1
Haug Dorenberg, D.2
Kristiansen, K.I.3
-
8
-
-
76649124891
-
Preemptive versus sequential prophylactic-preemptive treatment regimens for cytomegalovirus in renal transplantation: Comparison of treatment failure and antiviral resistance
-
Van der Beek MT, Berger SP, Vossen AC, et al. Preemptive versus sequential prophylactic-preemptive treatment regimens for cytomegalovirus in renal transplantation: comparison of treatment failure and antiviral resistance. Transplantation 2010; 89:320-326.
-
(2010)
Transplantation
, vol.89
, pp. 320-326
-
-
Van Der Beek, M.T.1
Berger, S.P.2
Vossen, A.C.3
-
9
-
-
79953312642
-
Diversity of antiviral-resistant human cytomegalovirus in heart and lung transplant recipients
-
Iwasenko JM, Scott GM, Naing Z, et al. Diversity of antiviral-resistant human cytomegalovirus in heart and lung transplant recipients. Transpl Infect Dis 2011; 13:145-153.
-
(2011)
Transpl Infect Dis
, vol.13
, pp. 145-153
-
-
Iwasenko, J.M.1
Scott, G.M.2
Naing, Z.3
-
10
-
-
77952596450
-
Recombinant phenotyping of cytomegalovirus UL97 kinase sequence variants for ganciclovir resistance
-
Chou S. Recombinant phenotyping of cytomegalovirus UL97 kinase sequence variants for ganciclovir resistance. Antimicrob Agents Chemother 2010; 54:2371-2378.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2371-2378
-
-
Chou, S.1
-
11
-
-
78149499784
-
Contrasting effects on ganciclovir susceptibility and replicative capacity of two mutations at codon 466 of the human cytomegalovirus UL97 gene
-
Martin M, Goyette N, Boivin G. Contrasting effects on ganciclovir susceptibility and replicative capacity of two mutations at codon 466 of the human cytomegalovirus UL97 gene. J Clin Virol 2010; 49:296-298.
-
(2010)
J Clin Virol
, vol.49
, pp. 296-298
-
-
Martin, M.1
Goyette, N.2
Boivin, G.3
-
12
-
-
77949491489
-
Incidence and characterization of cytomegalovirus resistance mutations among pediatric solid organ transplant patients who received valganciclovir prophylaxis
-
Martin M, Goyette N, Ives J, Boivin G. Incidence and characterization of cytomegalovirus resistance mutations among pediatric solid organ transplant patients who received valganciclovir prophylaxis. J Clin Virol 2010; 47:321-324.
-
(2010)
J Clin Virol
, vol.47
, pp. 321-324
-
-
Martin, M.1
Goyette, N.2
Ives, J.3
Boivin, G.4
-
13
-
-
77950468641
-
The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients
-
Humar A, Lebranchu Y, Vincenti F, et al. The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients. Am J Transplant 2010; 10:1228-1237.
-
(2010)
Am J Transplant
, vol.10
, pp. 1228-1237
-
-
Humar, A.1
Lebranchu, Y.2
Vincenti, F.3
-
14
-
-
77954070106
-
Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: A randomized, controlled trial
-
Palmer SM, Limaye AP, Banks M, et al. Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: A randomized, controlled trial. Ann Intern Med 2010; 152:761-769.
-
(2010)
Ann Intern Med
, vol.152
, pp. 761-769
-
-
Palmer, S.M.1
Limaye, A.P.2
Banks, M.3
-
15
-
-
78650812043
-
Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis
-
Chou S, Marousek G, Boivin G, et al. Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis. Transplantation 2010; 90:1409-1413.
-
(2010)
Transplantation
, vol.90
, pp. 1409-1413
-
-
Chou, S.1
Marousek, G.2
Boivin, G.3
-
16
-
-
78649650510
-
Improved detection of mutated human cytomegalovirus UL97 by pyrosequencing
-
Schindele B, Apelt L, Hofmann J, et al. Improved detection of mutated human cytomegalovirus UL97 by pyrosequencing. Antimicrob Agents Chemother 2010; 54:5234-5241.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 5234-5241
-
-
Schindele, B.1
Apelt, L.2
Hofmann, J.3
-
17
-
-
77953734114
-
Deep sequencing reveals highly complex dynamics of human cytomegalovirus genotypes in transplant patients over time
-
Gorzer I, Guelly C, Trajanoski S, Puchhammer-Stockl E. Deep sequencing reveals highly complex dynamics of human cytomegalovirus genotypes in transplant patients over time. J Virol 2010; 84:7195-7203.
-
(2010)
J Virol
, vol.84
, pp. 7195-7203
-
-
Gorzer, I.1
Guelly, C.2
Trajanoski, S.3
Puchhammer-Stockl, E.4
-
18
-
-
79953733120
-
Mass spectrometry-based comparative sequencing to detect ganciclovir resistance in the UL97 gene of human cytomegalovirus
-
Posthuma CC, van der Beek MT, van der Blij-de Brouwer CS, et al. Mass spectrometry-based comparative sequencing to detect ganciclovir resistance in the UL97 gene of human cytomegalovirus. J Clin Virol 2011; 51:25-30.
-
(2011)
J Clin Virol
, vol.51
, pp. 25-30
-
-
Posthuma, C.C.1
Van Der Beek, M.T.2
Van Der Blij-De Brouwer, C.S.3
-
19
-
-
78649646827
-
Differentiation between polymorphisms and resistance associated mutations in the human cytomegalovirus DNA polymerase
-
Chevillotte M, Ersing I, Mertens T, von Einem J. Differentiation between polymorphisms and resistance associated mutations in the human cytomegalovirus DNA polymerase. Antimicrob Agents Chemother 2010; 54:5004-5011.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 5004-5011
-
-
Chevillotte, M.1
Ersing, I.2
Mertens, T.3
Von Einem, J.4
-
20
-
-
79952618827
-
Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy
-
Chou S. Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy. J Clin Virol 2011; 50:287-291.
-
(2011)
J Clin Virol
, vol.50
, pp. 287-291
-
-
Chou, S.1
-
21
-
-
80051817678
-
Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet
-
Gilbert C, Azzi A, Goyette N, et al. Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. Antimicrob Agents Chemother 2011; 55:4019-4027.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 4019-4027
-
-
Gilbert, C.1
Azzi, A.2
Goyette, N.3
-
22
-
-
79957504008
-
Genotypic characterization of human cytomegalovirus UL97 phosphotransferase natural polymorphism in the era of ganciclovir and maribavir
-
Boutolleau D, Burrel S, Agut H. Genotypic characterization of human cytomegalovirus UL97 phosphotransferase natural polymorphism in the era of ganciclovir and maribavir. Antiviral Res 2011; 91:32-35.
-
(2011)
Antiviral Res
, vol.91
, pp. 32-35
-
-
Boutolleau, D.1
Burrel, S.2
Agut, H.3
-
23
-
-
69849110029
-
Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir
-
Boivin G,Goyette N, Rollag H, et al. Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir. Antivir Ther 2009; 14:697-704.
-
(2009)
Antivir Ther
, vol.14
, pp. 697-704
-
-
Boivin Ggoyette, N.1
Rollag, H.2
-
24
-
-
33745841864
-
Crystal structure of the herpes simplex virus 1 DNA polymerase
-
DOI 10.1074/jbc.M602414200
-
Liu S, Knafels JD, Chang JS, et al. Crystal structure of the herpes simplex virus 1 DNA polymerase. J Biol Chem 2006; 281:18193-18200. (Pubitemid 44035619)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.26
, pp. 18193-18200
-
-
Liu, S.1
Knafels, J.D.2
Chang, J.S.3
Waszak, G.A.4
Baldwin, E.T.5
Deibel Jr., M.R.6
Thomsen, D.R.7
Homa, F.L.8
Wells, P.A.9
Tory, M.C.10
Poorman, R.A.11
Gao, H.12
Qiu, X.13
Seddon, A.P.14
-
25
-
-
79952136133
-
Development of CMX001 for the treatment of poxvirus infections
-
Lanier R, Trost L, Tippin T, et al. Development of CMX001 for the treatment of poxvirus infections. Viruses 2010; 2:2740-2762.
-
(2010)
Viruses
, vol.2
, pp. 2740-2762
-
-
Lanier, R.1
Trost, L.2
Tippin, T.3
-
26
-
-
77955359554
-
Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir
-
Gentry BG, Kamil JP, Coen DM, et al. Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir. Antimicrob Agents Chemother 2010; 54:3093-3098.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3093-3098
-
-
Gentry, B.G.1
Kamil, J.P.2
Coen, D.M.3
-
27
-
-
78650664958
-
Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility
-
Chou S, Bowlin TL. Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility. Antimicrob Agents Chemother 2011; 55:382-384.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 382-384
-
-
Chou, S.1
Bowlin, T.L.2
-
28
-
-
79957595899
-
The effects of maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein
-
Shannon-Lowe CD, Emery VC. The effects of maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein. Herpesviridae 2010; 1:4.
-
(2010)
Herpesviridae
, vol.1
, pp. 4
-
-
Shannon-Lowe, C.D.1
Emery, V.C.2
-
29
-
-
34250795232
-
Cytomegalovirus UL97 kinase mutations that confer maribavir resistance
-
DOI 10.1086/518514
-
Chou S, Wechel LC, Marousek GI. Cytomegalovirus UL97 kinase mutations that confer maribavir resistance. J Infect Dis 2007; 196:91-94. (Pubitemid 46982742)
-
(2007)
Journal of Infectious Diseases
, vol.196
, Issue.1
, pp. 91-94
-
-
Chou, S.1
Van Wechel, L.C.2
Marousek, G.I.3
-
30
-
-
59749092000
-
Diverse cytomegalovirus UL27 mutations adapt to loss of viral UL97 kinase activity under maribavir
-
Chou S. Diverse cytomegalovirus UL27 mutations adapt to loss of viral UL97 kinase activity under maribavir. Antimicrob Agents Chemother 2009; 53:81-85.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 81-85
-
-
Chou, S.1
-
31
-
-
79951592516
-
Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest
-
Reitsma JM, Savaryn JP, Faust K, et al. Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest. Cell Host Microbe 2011; 9:103-114.
-
(2011)
Cell Host Microbe
, vol.9
, pp. 103-114
-
-
Reitsma, J.M.1
Savaryn, J.P.2
Faust, K.3
-
32
-
-
79953035666
-
Maribavir prophylaxis for prevention of cytomegalovirus disease in recipients of allogeneic stem-cell transplants: A phase 3, double-blind, placebo-controlled, randomised trial
-
Marty FM, Ljungman P, Papanicolaou GA, et al. Maribavir prophylaxis for prevention of cytomegalovirus disease in recipients of allogeneic stem-cell transplants: A phase 3, double-blind, placebo-controlled, randomised trial. Lancet Infect Dis 2011; 11:284-292.
-
(2011)
Lancet Infect Dis
, vol.11
, pp. 284-292
-
-
Marty, F.M.1
Ljungman, P.2
Papanicolaou, G.A.3
-
33
-
-
79953057416
-
Why did maribavir fail in stem-cell transplants?
-
Snydman DR. Why did maribavir fail in stem-cell transplants? Lancet Infect Dis 2011; 11:255-257.
-
(2011)
Lancet Infect Dis
, vol.11
, pp. 255-257
-
-
Snydman, D.R.1
-
34
-
-
33745589284
-
Effect of cell culture conditions on the anticytomegalovirus activity of maribavir
-
DOI 10.1128/AAC.00207-06
-
Chou S, Van Wechel LC, Marousek GI. Effect of cell culture conditions on the anticytomegalovirus activity of maribavir. Antimicrob Agents Chemother 2006; 50:2557-2559. (Pubitemid 43993205)
-
(2006)
Antimicrobial Agents and Chemotherapy
, vol.50
, Issue.7
, pp. 2557-2559
-
-
Chou, S.1
Van Wechel, L.C.2
Marousek, G.I.3
-
35
-
-
78650157268
-
Oral maribavir for treatment of refractory or resistant cytomegalovirus infections in transplant recipients
-
Avery RK,Marty FM, Strasfeld L, et al. Oral maribavir for treatment of refractory or resistant cytomegalovirus infections in transplant recipients. Transpl Infect Dis 2010; 12:489-496.
-
(2010)
Transpl Infect Dis
, vol.12
, pp. 489-496
-
-
Avery Rkmarty, F.M.1
Strasfeld, L.2
-
36
-
-
77953714487
-
Virologic characterization of multidrugresistant cytomegalovirus infection in two transplant recipients treated with maribavir
-
Strasfeld L, Lee I, Villano S, Chou S. Virologic characterization of multidrugresistant cytomegalovirus infection in two transplant recipients treated with maribavir. J Infect Dis 2010; 202:104-108.
-
(2010)
J Infect Dis
, vol.202
, pp. 104-108
-
-
Strasfeld, L.1
Lee, I.2
Villano, S.3
Chou, S.4
-
37
-
-
77149133052
-
Vitro and in vivo activities of the novel anticytomegalovirus compound AIC246
-
Lischka P, Hewlett G, Wunberg T, et al. In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246. Antimicrob Agents Chemother 2010; 54:1290-1297.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 1290-1297
-
-
Lischka, P.1
Hewlett, G.2
Wunberg, T.3
-
38
-
-
80055021608
-
The novel anticytomegalovirus compound AIC246 (letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase
-
Goldner T, Hewlett G, Ettischer N, et al. The novel anticytomegalovirus compound AIC246 (letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase. J Virol 2011; 85:10884-10893.
-
(2011)
J Virol
, vol.85
, pp. 10884-10893
-
-
Goldner, T.1
Hewlett, G.2
Ettischer, N.3
-
39
-
-
79955544310
-
First report of successful treatment of multidrug-resistant cytomegalovirus disease with the novel anti-CMV compound AIC246
-
Kaul DR, Stoelben S, Cober E, et al. First report of successful treatment of multidrug-resistant cytomegalovirus disease with the novel anti-CMV compound AIC246. Am J Transplant 2011; 11:1079-1084.
-
(2011)
Am J Transplant
, vol.11
, pp. 1079-1084
-
-
Kaul, D.R.1
Stoelben, S.2
Cober, E.3
|