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Volumn 102, Issue 11, 2011, Pages 2103-2107

Cyclin D2 is overexpressed in proliferation centers of chronic lymphocytic leukemia/small lymphocytic lymphoma

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D2; CYCLIN D3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYC PROTEIN; PROTEIN P15; PROTEIN P16; PROTEIN P18; PROTEIN P27;

EID: 80054969575     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2011.02046.x     Document Type: Article
Times cited : (32)

References (49)
  • 1
    • 0028171292 scopus 로고
    • 1 phase progression: cycling on cue
    • 1 phase progression: cycling on cue. Cell 1994; 79: 551-5.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 2
    • 60749109846 scopus 로고    scopus 로고
    • Cell cycle, CDKs and cancer: a changing paradigm
    • Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 2009; 9: 153-66.
    • (2009) Nat Rev Cancer , vol.9 , pp. 153-166
    • Malumbres, M.1    Barbacid, M.2
  • 3
    • 0030561571 scopus 로고    scopus 로고
    • The retinoblastoma protein pathway and the restriction point
    • Bartek J, Bartkova J, Lukas J. The retinoblastoma protein pathway and the restriction point. Curr Opin Cell Biol 1996; 8: 805-14.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 805-814
    • Bartek, J.1    Bartkova, J.2    Lukas, J.3
  • 4
    • 0032823963 scopus 로고    scopus 로고
    • Selective usage of D-type cyclins in lymphoid malignancies
    • Suzuki R, Kuroda H, Komatsu H et al. Selective usage of D-type cyclins in lymphoid malignancies. Leukemia 1999; 13: 1335-42.
    • (1999) Leukemia , vol.13 , pp. 1335-1342
    • Suzuki, R.1    Kuroda, H.2    Komatsu, H.3
  • 5
    • 0013439945 scopus 로고    scopus 로고
    • Cycling to cancer with cyclin D1
    • Diehl JA. Cycling to cancer with cyclin D1. Cancer Biol Ther 2002; 1: 226-31.
    • (2002) Cancer Biol Ther , vol.1 , pp. 226-231
    • Diehl, J.A.1
  • 6
    • 12944252972 scopus 로고    scopus 로고
    • Significance of cyclin D1 overexpression for the diagnosis of mantle cell lymphoma: a clinicopathologic comparison of cyclin D1-positive MCL and cyclin D1-negative MCL-like B-cell lymphoma
    • Yatabe Y, Suzuki R, Tobinai K et al. Significance of cyclin D1 overexpression for the diagnosis of mantle cell lymphoma: a clinicopathologic comparison of cyclin D1-positive MCL and cyclin D1-negative MCL-like B-cell lymphoma. Blood 2000; 95: 2253-61.
    • (2000) Blood , vol.95 , pp. 2253-2261
    • Yatabe, Y.1    Suzuki, R.2    Tobinai, K.3
  • 7
    • 28844449677 scopus 로고    scopus 로고
    • Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling
    • Fu K, Weisenburger DD, Greiner TC et al. Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling. Blood 2005; 106: 4315-21.
    • (2005) Blood , vol.106 , pp. 4315-4321
    • Fu, K.1    Weisenburger, D.D.2    Greiner, T.C.3
  • 8
    • 80055023090 scopus 로고    scopus 로고
    • SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype
    • Mozos A. SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype. Haematologica 2010; 95: 1620.
    • (2010) Haematologica , vol.95 , pp. 1620
    • Mozos, A.1
  • 9
    • 0032913403 scopus 로고    scopus 로고
    • Expression of cyclin D2 and D3 in lymphoid lesions
    • Teramoto N, Pokrovskaja K, Szekely L et al. Expression of cyclin D2 and D3 in lymphoid lesions. Int J Cancer 1999; 81: 543-50.
    • (1999) Int J Cancer , vol.81 , pp. 543-550
    • Teramoto, N.1    Pokrovskaja, K.2    Szekely, L.3
  • 10
    • 77649272309 scopus 로고    scopus 로고
    • Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes
    • Metcalf RA, Zhao SC, Anderson MW et al. Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes. Mod Pathol 2010; 23: 420-33.
    • (2010) Mod Pathol , vol.23 , pp. 420-433
    • Metcalf, R.A.1    Zhao, S.C.2    Anderson, M.W.3
  • 11
    • 13844307760 scopus 로고    scopus 로고
    • Mechanisms of disease: chronic lymphocytic leukemia
    • Chiorazzi N, Rai KR, Ferrarini M. Mechanisms of disease: chronic lymphocytic leukemia. N Engl J Med 2005; 352: 804-15.
    • (2005) N Engl J Med , vol.352 , pp. 804-815
    • Chiorazzi, N.1    Rai, K.R.2    Ferrarini, M.3
  • 12
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V-H genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V-H genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999; 94: 1848-54.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 13
    • 10744222814 scopus 로고    scopus 로고
    • ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile
    • Wiestner A, Rosenwald A, Barry TS et al. ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood 2003; 101: 4944-51.
    • (2003) Blood , vol.101 , pp. 4944-4951
    • Wiestner, A.1    Rosenwald, A.2    Barry, T.S.3
  • 14
    • 78049452623 scopus 로고    scopus 로고
    • Immunohistochemical detection of ZAP70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression
    • Admirand JH, Knoblock RJ, Coombes KR et al. Immunohistochemical detection of ZAP70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression. Mod Pathol 2010; 23: 1518-23.
    • (2010) Mod Pathol , vol.23 , pp. 1518-1523
    • Admirand, J.H.1    Knoblock, R.J.2    Coombes, K.R.3
  • 15
    • 0029038529 scopus 로고
    • Overexpression of cyclin D2 in chronic B-cell malignancies
    • Delmer A, Ajchenbaumcymbalista F, Tang RP et al. Overexpression of cyclin D2 in chronic B-cell malignancies. Blood 1995; 85: 2870-6.
    • (1995) Blood , vol.85 , pp. 2870-2876
    • Delmer, A.1    Ajchenbaumcymbalista, F.2    Tang, R.P.3
  • 16
    • 0036124281 scopus 로고    scopus 로고
    • Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27
    • Decker T, Schneller F, Hipp S et al. Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27. Leukemia 2002; 16: 327-34.
    • (2002) Leukemia , vol.16 , pp. 327-334
    • Decker, T.1    Schneller, F.2    Hipp, S.3
  • 17
    • 75649083464 scopus 로고    scopus 로고
    • Is cyclin D2 a marker of B-CLL cell activation?
    • Kosmaczewska A, Ciszak L, Szteblich A et al. Is cyclin D2 a marker of B-CLL cell activation? Oncol Res 2009; 18: 127-31.
    • (2009) Oncol Res , vol.18 , pp. 127-131
    • Kosmaczewska, A.1    Ciszak, L.2    Szteblich, A.3
  • 18
    • 0024505946 scopus 로고
    • Small lymphocytic lymphoma: a clinicopathologic analysis of 268 cases
    • Benezra J, Burke JS, Swartz WG et al. Small lymphocytic lymphoma: a clinicopathologic analysis of 268 cases. Blood 1989; 73: 579-87.
    • (1989) Blood , vol.73 , pp. 579-587
    • Benezra, J.1    Burke, J.S.2    Swartz, W.G.3
  • 19
    • 52449121246 scopus 로고    scopus 로고
    • Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease?
    • Caligaris-Cappio F, Ghia P. Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease? J Clin Oncol 2008; 26: 4497-503.
    • (2008) J Clin Oncol , vol.26 , pp. 4497-4503
    • Caligaris-Cappio, F.1    Ghia, P.2
  • 20
    • 77956801193 scopus 로고    scopus 로고
    • Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia ("accelerated" chronic lymphocytic leukemia) with aggressive clinical behavior
    • Gine E, Martinez A, Villamor N et al. Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia ("accelerated" chronic lymphocytic leukemia) with aggressive clinical behavior. Haematologica 2010; 95: 1526-33.
    • (2010) Haematologica , vol.95 , pp. 1526-1533
    • Gine, E.1    Martinez, A.2    Villamor, N.3
  • 21
    • 0036277311 scopus 로고    scopus 로고
    • Multiple cell cycle regulator alterations in Richter's transformation of chronic lymphocytic leukemia
    • Cobo F, Martinez A, Pinyol M et al. Multiple cell cycle regulator alterations in Richter's transformation of chronic lymphocytic leukemia. Leukemia 2002; 16: 1028-34.
    • (2002) Leukemia , vol.16 , pp. 1028-1034
    • Cobo, F.1    Martinez, A.2    Pinyol, M.3
  • 22
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • Hallek M, Cheson BD, Catovsky D et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 2008; 111: 5446-56.
    • (2008) Blood , vol.111 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 23
    • 20144363564 scopus 로고    scopus 로고
    • Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms
    • Carreras J, Villamor N, Colomo L et al. Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms. J Pathol 2005; 205: 507-13.
    • (2005) J Pathol , vol.205 , pp. 507-513
    • Carreras, J.1    Villamor, N.2    Colomo, L.3
  • 24
    • 0035525731 scopus 로고    scopus 로고
    • Clinical significance of CD38 expression in chronic lymphocytic leukemia
    • Del Poeta G, Maurillo L, Venditti A et al. Clinical significance of CD38 expression in chronic lymphocytic leukemia. Blood 2001; 98: 2633-9.
    • (2001) Blood , vol.98 , pp. 2633-2639
    • Del Poeta, G.1    Maurillo, L.2    Venditti, A.3
  • 25
    • 0029026932 scopus 로고
    • Cyclin D1 protein-analysis in the diagnosis of mantle cell lymphoma
    • Deboer CJ, Schuuring E, Dreef E et al. Cyclin D1 protein-analysis in the diagnosis of mantle cell lymphoma. Blood 1995; 86: 2715-23.
    • (1995) Blood , vol.86 , pp. 2715-2723
    • Deboer, C.J.1    Schuuring, E.2    Dreef, E.3
  • 26
    • 11844253779 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia/small lymphocytic lymphoma with trisomy 12 and focal cyclin D1 expression: a potential diagnostic pitfall
    • O'Malley DP, Vance GH, Orazi A. Chronic lymphocytic leukemia/small lymphocytic lymphoma with trisomy 12 and focal cyclin D1 expression: a potential diagnostic pitfall. Arch Pathol Lab Med 2005; 129: 92-5.
    • (2005) Arch Pathol Lab Med , vol.129 , pp. 92-95
    • O'Malley, D.P.1    Vance, G.H.2    Orazi, A.3
  • 27
    • 17544395426 scopus 로고    scopus 로고
    • Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development
    • Solvason N, Wu WW, Parry D et al. Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development. Int Immunol 2000; 12: 631-8.
    • (2000) Int Immunol , vol.12 , pp. 631-638
    • Solvason, N.1    Wu, W.W.2    Parry, D.3
  • 28
    • 30444451801 scopus 로고    scopus 로고
    • Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia
    • Mayr C, Speicher MR, Kofler DM et al. Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia. Blood 2006; 107: 742-51.
    • (2006) Blood , vol.107 , pp. 742-751
    • Mayr, C.1    Speicher, M.R.2    Kofler, D.M.3
  • 29
    • 0032872129 scopus 로고    scopus 로고
    • Cyclin D2 promoter disrupted by t(12;22)(p13;q11.2) during transformation of chronic lymphocytic leukaemia to non-Hodgkin's lymphoma
    • Qian L, Gong J, Liu J, Broome JD, Koduru PRK. Cyclin D2 promoter disrupted by t(12;22)(p13;q11.2) during transformation of chronic lymphocytic leukaemia to non-Hodgkin's lymphoma. Br J Haematol 1999; 106: 477-85.
    • (1999) Br J Haematol , vol.106 , pp. 477-485
    • Qian, L.1    Gong, J.2    Liu, J.3    Broome, J.D.4    Koduru, P.R.K.5
  • 30
    • 4344593761 scopus 로고    scopus 로고
    • Regulation and function of cyclin D2 in B lymphocyte subsets
    • Chiles TC. Regulation and function of cyclin D2 in B lymphocyte subsets. J Immunol 2004; 173: 2901-7.
    • (2004) J Immunol , vol.173 , pp. 2901-2907
    • Chiles, T.C.1
  • 31
    • 60149094697 scopus 로고    scopus 로고
    • Rel A is an independent biomarker of clinical outcome in chronic lymphocytic leukemia
    • Hewamana S, Lin TT, Rowntree C et al. Rel A is an independent biomarker of clinical outcome in chronic lymphocytic leukemia. J Clin Oncol 2009; 27: 763-9.
    • (2009) J Clin Oncol , vol.27 , pp. 763-769
    • Hewamana, S.1    Lin, T.T.2    Rowntree, C.3
  • 32
    • 73349132384 scopus 로고    scopus 로고
    • NF-kappa B as a prognostic marker and therapeutic target in chronic lymphocytic leukemia
    • Pepper C, Hewamana S, Brennan P, Fegan C. NF-kappa B as a prognostic marker and therapeutic target in chronic lymphocytic leukemia. Future Oncol 2009; 5: 1027-37.
    • (2009) Future Oncol , vol.5 , pp. 1027-1037
    • Pepper, C.1    Hewamana, S.2    Brennan, P.3    Fegan, C.4
  • 34
    • 0036928333 scopus 로고    scopus 로고
    • B cell growth is controlled by phosphatidylinosotol 3-kinase-dependent Rel/NF-kappa B regulated induction of c-myc transcription
    • Grumont RJ, Strasser A, Gerondakis S. B cell growth is controlled by phosphatidylinosotol 3-kinase-dependent Rel/NF-kappa B regulated induction of c-myc transcription. Mol Cell 2002; 10: 1283-94.
    • (2002) Mol Cell , vol.10 , pp. 1283-1294
    • Grumont, R.J.1    Strasser, A.2    Gerondakis, S.3
  • 35
    • 0028899112 scopus 로고
    • Role of rel-related factors in control of c-myc gene-transcription in receptor-mediated apoptosis of the murine B-cell WEHI-231 line
    • Lee HY, Arsura M, Wu M, Duyao M, Buckler AJ, Sonenshein GE. Role of rel-related factors in control of c-myc gene-transcription in receptor-mediated apoptosis of the murine B-cell WEHI-231 line. J Exp Med 1995; 181: 1169-77.
    • (1995) J Exp Med , vol.181 , pp. 1169-1177
    • Lee, H.Y.1    Arsura, M.2    Wu, M.3    Duyao, M.4    Buckler, A.J.5    Sonenshein, G.E.6
  • 36
    • 0033214080 scopus 로고    scopus 로고
    • Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27
    • Bouchard C, Thieke K, Maier A et al. Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27. EMBO J 1999; 18: 5321-33.
    • (1999) EMBO J , vol.18 , pp. 5321-5333
    • Bouchard, C.1    Thieke, K.2    Maier, A.3
  • 37
    • 0034724389 scopus 로고    scopus 로고
    • Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
    • Coller HA, Grandori C, Tamayo P et al. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc Natl Acad Sci USA 2000; 97: 3260-5.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3260-3265
    • Coller, H.A.1    Grandori, C.2    Tamayo, P.3
  • 38
    • 78549270421 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia
    • Danilov AV, Danilova OV, Brown JR, Rabinowitz A, Klein AK, Huber BT. Dipeptidyl peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia. Exp Hematol 2010; 38: 1167-77.
    • (2010) Exp Hematol , vol.38 , pp. 1167-1177
    • Danilov, A.V.1    Danilova, O.V.2    Brown, J.R.3    Rabinowitz, A.4    Klein, A.K.5    Huber, B.T.6
  • 39
    • 0037075887 scopus 로고    scopus 로고
    • Cyclin D-dependent kinases, INK4 inhibitors and cancer
    • Ortega S, Malumbres M, Barbacid M. Cyclin D-dependent kinases, INK4 inhibitors and cancer. Biochim Biophys Acta 2002; 1602: 73-87.
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 73-87
    • Ortega, S.1    Malumbres, M.2    Barbacid, M.3
  • 40
    • 73649145175 scopus 로고    scopus 로고
    • The function of p27(KIP1) during tumor development
    • Lee J, Kim SS. The function of p27(KIP1) during tumor development. Exp Mol Med 2009; 41: 765-71.
    • (2009) Exp Mol Med , vol.41 , pp. 765-771
    • Lee, J.1    Kim, S.S.2
  • 41
    • 0034744957 scopus 로고    scopus 로고
    • Repression of p15(INK4b) expression by Myc through association with Miz-1
    • Staller P, Peukert K, Kiermaier A et al. Repression of p15(INK4b) expression by Myc through association with Miz-1. Nat Cell Biol 2001; 3: 392-9.
    • (2001) Nat Cell Biol , vol.3 , pp. 392-399
    • Staller, P.1    Peukert, K.2    Kiermaier, A.3
  • 42
    • 0032824069 scopus 로고    scopus 로고
    • Analysis of the immunoglobulin heavy chain gene variable region of 101 cases with peripheral B cell neoplasms and B cell chronic lymphocytic leukemia in the Japanese population
    • Nakamura N, Kuze T, Hashimoto Y et al. Analysis of the immunoglobulin heavy chain gene variable region of 101 cases with peripheral B cell neoplasms and B cell chronic lymphocytic leukemia in the Japanese population. Pathol Int 1999; 49: 595-600.
    • (1999) Pathol Int , vol.49 , pp. 595-600
    • Nakamura, N.1    Kuze, T.2    Hashimoto, Y.3
  • 43
    • 33746924345 scopus 로고    scopus 로고
    • Survival response to B-cell receptor ligation is restricted to progressive chronic lymphocytic leukemia cells irrespective of Zap70 expression
    • Deglesne PA, Chevallier N, Letestu R et al. Survival response to B-cell receptor ligation is restricted to progressive chronic lymphocytic leukemia cells irrespective of Zap70 expression. Cancer Res 2006; 66: 7158-66.
    • (2006) Cancer Res , vol.66 , pp. 7158-7166
    • Deglesne, P.A.1    Chevallier, N.2    Letestu, R.3
  • 44
    • 33746589459 scopus 로고    scopus 로고
    • Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia
    • Del Principe MI, Del Poeta G, Buccisano F et al. Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia. Blood 2006; 108: 853-61.
    • (2006) Blood , vol.108 , pp. 853-861
    • Del Principe, M.I.1    Del Poeta, G.2    Buccisano, F.3
  • 45
    • 0035412375 scopus 로고    scopus 로고
    • CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia
    • Ibrahim S, Keating M, Do KA et al. CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia. Blood 2001; 98: 181-6.
    • (2001) Blood , vol.98 , pp. 181-186
    • Ibrahim, S.1    Keating, M.2    Do, K.A.3
  • 46
    • 33747187494 scopus 로고    scopus 로고
    • In-tandem insight from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemia
    • Deaglio S, Vaisitti T, Aydin S, Ferrero E, Malavasi F. In-tandem insight from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemia. Blood 2006; 108: 1135-44.
    • (2006) Blood , vol.108 , pp. 1135-1144
    • Deaglio, S.1    Vaisitti, T.2    Aydin, S.3    Ferrero, E.4    Malavasi, F.5
  • 47
    • 0037114744 scopus 로고    scopus 로고
    • Expression of ZAP-70 is associated with increased B cell receptor signaling in chronic lymphocytic leukemia
    • Chen L, Widhopf G, Huynh L et al. Expression of ZAP-70 is associated with increased B cell receptor signaling in chronic lymphocytic leukemia. Blood 2002; 100: 4609-14.
    • (2002) Blood , vol.100 , pp. 4609-4614
    • Chen, L.1    Widhopf, G.2    Huynh, L.3
  • 48
    • 36148978171 scopus 로고    scopus 로고
    • Signaling pathways activated by antigen-receptor engagement in chronic lymphocytic leukemia B-cells
    • Efremov DG, Gobessi S, Longo PG. Signaling pathways activated by antigen-receptor engagement in chronic lymphocytic leukemia B-cells. Autoimmun Rev 2007; 7: 102-8.
    • (2007) Autoimmun Rev , vol.7 , pp. 102-108
    • Efremov, D.G.1    Gobessi, S.2    Longo, P.G.3
  • 49
    • 28844497059 scopus 로고    scopus 로고
    • CD38 ligation in B-chronic lymphocytic leukemia cells induces sequential tyrosine phosphorylation of ZAP70, PLC-gamma 2 and ERK1/2 proteins (Abstract)
    • Deaglio S, Vaisitti T, Malavasi F. CD38 ligation in B-chronic lymphocytic leukemia cells induces sequential tyrosine phosphorylation of ZAP70, PLC-gamma 2 and ERK1/2 proteins (Abstract). Blood 2004; 104: A274-5.
    • (2004) Blood , vol.104
    • Deaglio, S.1    Vaisitti, T.2    Malavasi, F.3


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