Ebf1 deficiency causes increase of Müller cells in the retina and abnormal topographic projection at the optic chiasm

Biochemical and Biophysical Research Communications

Volumn 414, Issue 3, 2011, Pages 539-544

  Jin, Kangxin ^a   Xiang, Mengqing ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Axon projection; Early B cell factor; Ebf1; Knockout; Optic chiasm; Retinal development; Retinal ganglion cell

Indexed keywords

EBF1 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; IN VITRO STUDY; MOUSE; MUELLER CELL; NONHUMAN; OPTIC CHIASM; OPTIC TRACT; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; RETINA DEVELOPMENT; RETINA GANGLION CELL; TOPOGRAPHY;

ANIMALS; AXONS; MICE; MICE, INBRED C57BL; MUTATION; NEUROGENESIS; OPTIC CHIASM; RETINA; RETINAL GANGLION CELLS; TRANS-ACTIVATORS;

MUS;

EID: 80054962648     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.09.108     Document Type: Article

References (41)

1. Masland R.H. Neuronal diversity in the retina. Curr. Opin. Neurobiol. 2001, 11:431-436.
2. Masland R.H. The fundamental plan of the retina. Nat. Neurosci. 2001, 4:877-886.
3. Cepko C.L. The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates. Curr. Opin. Neurobiol. 1999, 9:37-46.
4. Livesey F.J., Cepko C.L. Vertebrate neural cell-fate determination: lessons from the retina. Nat. Rev. Neurosci. 2001, 2:109-118.
5. Petros T.J., Rebsam A., Mason C.A. Retinal axon growth at the optic chiasm: to cross or not to cross. Annu. Rev. Neurosci. 2008, 31:295-315.
6. Erskine L., Herrera E. The retinal ganglion cell axon's journey: insights into molecular mechanisms of axon guidance. Dev. Biol. 2007, 308:1-14.
7. Pratt T., Conway C.D., Tian N.M., Price D.J., Mason J.O. Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm. J. Neurosci. 2006, 26:6911-6923.
8. Bunt S.M., Lund R.D. Development of a transient retino-retinal pathway in hooded and albino rats. Brain Res. 1981, 211:399-404.
9. McLoon S.C., Lund R.D. Transient retinofugal pathways in the developing chick. Exp. Brain Res. 1982, 45:277-284.
10. Plump A.S., Erskine L., Sabatier C., Brose K., Epstein C.J., Goodman C.S., Mason C.A., Tessier-Lavigne M. Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron 2002, 33:219-232.
11. Williams S.E., Mann F., Erskine L., Sakurai T., Wei S., Rossi D.J., Gale N.W., Holt C.E., Mason C.A., Henkemeyer M. Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm. Neuron 2003, 39:919-935.
12. Nakagawa S., Brennan C., Johnson K.G., Shewan D., Harris W.A., Holt C.E. Ephrin-B regulates the Ipsilateral routing of retinal axons at the optic chiasm. Neuron 2000, 25:599-610.
13. Zelina P., Avci H.X., Thelen K., Pollerberg G.E. The cell adhesion molecule NrCAM is crucial for growth cone behaviour and pathfinding of retinal ganglion cell axons. Development 2005, 132:3609-3618.
14. Herrera E., Brown L., Aruga J., Rachel R.A., Dolen G., Mikoshiba K., Brown S., Mason C.A. Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell 2003, 114:545-557.
15. Lee R., Petros T.J., Mason C.A. Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1. J. Neurosci. 2008, 28:5910-5919.
16. Herrera E., Marcus R., Li S., Williams S.E., Erskine L., Lai E., Mason C. Foxd1 is required for proper formation of the optic chiasm. Development 2004, 131:5727-5739.
17. Garel S., Marin F., Mattei M.G., Vesque C., Vincent A., Charnay P. Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system. Dev. Dyn. 1997, 210:191-205.
18. Bally-Cuif L., Dubois L., Vincent A. Molecular cloning of Zcoe2, the zebrafish homolog of Xenopus Xcoe2 and mouse EBF-2, and its expression during primary neurogenesis. Mech. Dev. 1998, 77:85-90.
19. Dubois L., Bally-Cuif L., Crozatier M., Moreau J., Paquereau L., Vincent A. XCoe2, a transcription factor of the Col/Olf-1/EBF family involved in the specification of primary neurons in Xenopus. Curr. Biol. 1998, 8:199-209.
20. Akerblad P., Mansson R., Lagergren A., Westerlund S., Basta B., Lind U., Thelin A., Gisler R., Liberg D., Nelander S., Bamberg K., Sigvardsson M. Gene expression analysis suggests that EBF-1 and PPARgamma2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics. Physiol. Genomics 2005, 23:206-216.
21. Jimenez M.A., Akerblad P., Sigvardsson M., Rosen E.D. Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade. Mol. Cell. Biol. 2007, 27:743-757.
22. Lin H., Grosschedl R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 1995, 376:263-267.
23. Romanow W.J., Langerak A.W., Goebel P., Wolvers-Tettero I.L., van Dongen J.J., Feeney A.J., Murre C. E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells. Mol. Cell. 2000, 5:343-353.
24. Jin K., Jiang H., Mo Z., Xiang M. Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J. Neurosci. 2010, 30:11902-11916.
25. Tomita K., Nakanishi S., Guillemot F., Kageyama R. Mash1 promotes neuronal differentiation in the retina. Genes Cells 1996, 1:765-774.
26. Li S., Mo Z., Yang X., Price S.M., Shen M.M., Xiang M. Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors. Neuron 2004, 43:795-807.
27. Wang S.S., Lewcock J.W., Feinstein P., Mombaerts P., Reed R.R. Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection. Development 2004, 131:1377-1388.
28. Garel S., Yun K., Grosschedl R., Rubenstein J.L. The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development 2002, 129:5621-5634.
29. -/- mice. Neurobiol. Dis. 2011, 42:73-84.
30. Prasad B.C., Ye B., Zackhary R., Schrader K., Seydoux G., Reed R.R. Unc-3, a gene required for axonal guidance in Caenorhabditis elegans, encodes a member of the O/E family of transcription factors. Development 1998, 125:1561-1568.
31. Nieminen P., Liippo J., Lassila O. Pax-5 and EBF are expressed in committed B-cell progenitors prior to the colonization of the embryonic bursa of fabricius. Scand. J. Immunol. 2000, 52:465-469.
32. Akerblad P., Lind U., Liberg D., Bamberg K., Sigvardsson M. Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation. Mol. Cell. Biol. 2002, 22:8015-8025.
33. Croci L., Chung S.H., Masserdotti G., Gianola S., Bizzoca A., Gennarini G., Corradi A., Rossi F., Hawkes R., Consalez G.G. A key role for the HLH transcription factor EBF2COE2, O/E-3 in Purkinje neuron migration and cerebellar cortical topography. Development 2006, 133:2719-2729.
34. Garel S., Marin F., Grosschedl R., Charnay P. Ebf1 controls early cell differentiation in the embryonic striatum. Development 1999, 126:5285-5294.
35. Inoue T., Hojo M., Bessho Y., Tano Y., Lee J.E., Kageyama R. Math3 and NeuroD regulate amacrine cell fate specification in the retina. Development 2002, 129:831-842.
36. Akagi T., Inoue T., Miyoshi G., Bessho Y., Takahashi M., Lee J.E., Guillemot F., Kageyama R. Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification. J. Biol. Chem. 2004, 279:28492-28498.
37. Brown N.L., Kanekar S., Vetter M.L., Tucker P.K., Gemza D.L., Glaser T. Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. Development 1998, 125:4821-4833.
38. Cai L., Morrow E.M., Cepko C.L. Misexpression of basic helix-loop-helix genes in the murine cerebral cortex affects cell fate choices and neuronal survival. Development 2000, 127:3021-3030.
39. Inatani M., Irie F., Plump A.S., Tessier-Lavigne M., Yamaguchi Y. Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science 2003, 302:1044-1046.
40. Pratt T., Tian N.M., Simpson T.I., Mason J.O., Price D.J. The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse. Development 2004, 131:3773-3784.
41. Tian N.M., Pratt T., Price D.J. Foxg1 regulates retinal axon pathfinding by repressing an ipsilateral program in nasal retina and by causing optic chiasm cells to exert a net axonal growth-promoting activity. Development 2008, 135:4081-4089.