Genotype-independent in vivo oxidative stress following a methionine loading test: Maximal platelet activation in subjects with early-onset thrombosis

Thrombosis Research

Volumn 128, Issue 4, 2011, Pages

  Di Minno, Matteo Nicola Dario ^a   Pezzullo, Salvatore ^a   Palmieri, Vittorio ^a   Coppola, Antonio ^a   D'Angelo, Armando ^b   Sampietro, Francesca ^b   Cavalca, Viviana ^c   Tremoli, Elena ^c   Di Minno, Giovanni ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b IRCCSHS Raffaele   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

history of early onset thrombosis; homocysteine; methionine loading test; oxidative stress; platelet activation

Indexed keywords

11 OXOTHROMBOXANE B2; 5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); 8 ISOPROSTAGLANDIN F2 ALPHA; CYSTATHIONINE BETA SYNTHASE; HOMOCYSTEINE; METHIONINE;

ADULT; ARTERY THROMBOSIS; ARTICLE; CONTROLLED STUDY; EARLY ONSET THROMBOSIS; FEMALE; GENE EXPRESSION; GENE MUTATION; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; LOADING TEST; MAJOR CLINICAL STUDY; MALE; METHIONINE LOADING TEST; ONSET AGE; OXIDATIVE STRESS; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOEMBOLISM; THROMBOSIS; URINARY EXCRETION; VEIN THROMBOSIS;

ADULT; AGE OF ONSET; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CYSTATHIONINE BETA-SYNTHASE; DINOPROST; FEMALE; HOMOCYSTEINE; HOMOZYGOTE; HUMANS; HYPERHOMOCYSTEINEMIA; ITALY; LINEAR MODELS; MALE; METHIONINE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; MUTATION; OXIDATIVE STRESS; PHENOTYPE; PLATELET ACTIVATION; PLATELET FUNCTION TESTS; THROMBOSIS; THROMBOXANE B2; TIME FACTORS;

EID: 80054949333     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.05.017     Document Type: Article

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