Simultaneous quantification of 8-iso-prostaglandin-F2α and 11-dehydro thromboxane B2 in human urine by liquid chromatography-tandem mass spectrometry

Analytical Biochemistry

Volumn 397, Issue 2, 2010, Pages 168-174

  Cavalca, Viviana ^a,b   Minardi, Fabiana ^b   Scurati, Samuele ^c   Guidugli, Federico ^c   Squellerio, Isabella ^b   Veglia, Fabrizio ^b   Dainese, Luca ^b   Guarino, Anna ^b   Tremoli, Elena ^a,b   Caruso, Donatella ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b CENTRO CARDIOLOGICO MONZINO   (Italy)

^c Thermo Fisher Scientific   (United States)

Author keywords

Carotid artery stenosis; Liquid chromatography tandem mass spectrometry; Oxidative stress; Platelet aggregation

Indexed keywords

DISEASE CONTROL; ELECTROSPRAY IONIZATION; LIQUIDS; MASS SPECTROMETRY; METABOLITES; NEGATIVE IONS; OXIDATIVE STRESS; PLATELETS;

CAROTID ARTERY STENOSIS; DISEASE PROGRESSION; HUMAN URINE SAMPLES; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; PLATELET ACTIVATION; PLATELET AGGREGATION; SIMULTANEOUS DETERMINATIONS; SIMULTANEOUS MEASUREMENT;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

11 OXOTHROMBOXANE B2; 8 ISOPROSTAGLANDIN F2 ALPHA;

ACCURACY; AGED; ANALYTIC METHOD; ARTICLE; ATHEROSCLEROSIS; CALIBRATION; CAROTID ARTERY OBSTRUCTION; CHEMICAL STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; METABOLITE; NEGATIVE ION ELECTROSPRAY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROCESS DEVELOPMENT; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; THROMBOCYTE AGGREGATION; URINALYSIS; URINE LEVEL; VALIDATION STUDY;

EID: 72149133371     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.10.014     Document Type: Article

References (32)

1. Yin H., Porter N.A., and Morrow J.D. Separation and identification of F2-isoprostane regioisomers and diastereomers by novel liquid chromatographic/mass spectrometric methods. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 827 (2005) 157-164
2. Cracowski J.L., Durand T., and Bessard G. Isoprostanes as a biomarker of lipid peroxidation in humans: physiology, pharmacology and clinical implications. Trends Pharmacol. Sci. 23 (2002) 360-366
3. Irizarry M.C., Yao Y., Hyman B.T., Growdon J.H., and Pratico D. Plasma F2A isoprostane levels in Alzheimer's and Parkinson's disease. Neurodegener. Dis. 4 (2007) 403-405
4. Nakahata N. Thromboxane A2: physiology/pathophysiology, cellular signal transduction and pharmacology. Pharmacol. Ther. 118 (2008) 18-35
5. Basu S. F2-isoprostanes in human health and diseases: from molecular mechanisms to clinical implications. Antioxid. Redox Signal. 10 (2008) 1405-1434
6. Sametz W., Prasthofer S., Wintersteiger R., and Juan H. Vascular effects of isoprostanes after endothelial damage. Prostaglandins Leukot. Essent. Fatty Acids 61 (1999) 369-372
7. Morrow J.D. The isoprostanes-unique products of arachidonate peroxidation: their role as mediators of oxidant stress. Curr. Pharm. Des. 12 (2006) 895-902
8. Ferroni P., Basili S., Falco A., and Davi G. Platelet activation in type 2 diabetes mellitus. J. Thromb. Haemost. 2 (2004) 1282-1291
9. Patrono C., and FitzGerald G.A. Isoprostanes: potential markers of oxidant stress in atherothrombotic disease. Arterioscler. Thromb. Vasc. Biol. 17 (1997) 2309-2315
10. Audoly L.P., Rocca B., Fabre J.E., Koller B.H., Thomas D., Loeb A.L., Coffman T.M., and FitzGerald G.A. Cardiovascular responses to the isoprostanes iPF(2alpha)-III and iPE(2)-III are mediated via the thromboxane A(2) receptor in vivo. Circulation 101 (2000) 2833-2840
11. Khasawneh F.T., Huang J.S., Mir F., Srinivasan S., Tiruppathi C., and Le Breton G.C. Characterization of isoprostane signaling: evidence for a unique coordination profile of 8-iso-PGF(2alpha) with the thromboxane A(2) receptor, and activation of a separate cAMP-dependent inhibitory pathway in human platelets. Biochem. Pharmacol. 75 (2008) 2301-2315
12. Dogne J.M., Hanson J., and Pratico D. Thromboxane, prostacyclin and isoprostanes: therapeutic targets in atherogenesis. Trends Pharmacol. Sci. 26 (2005) 639-644
13. Minuz P., Fava C., and Lechi A. Lipid peroxidation, isoprostanes and vascular damage. Pharmacol. Rep. 58 Suppl. (2006) 57-68
14. Davi G., Ciabattoni G., Consoli A., Mezzetti A., Falco A., Santarone S., Pennese E., Vitacolonna E., Bucciarelli T., Costantini F., Capani F., and Patrono C. In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. Circulation 99 (1999) 224-229
15. Davi G., Di Minno G., Coppola A., Andria G., Cerbone A.M., Madonna P., Tufano A., Falco A., Marchesani P., Ciabattoni G., and Patrono C. Oxidative stress and platelet activation in homozygous homocystinuria. Circulation 104 (2001) 1124-1128
16. Davi G., Guagnano M.T., Ciabattoni G., Basili S., Falco A., Marinopiccoli M., Nutini M., Sensi S., and Patrono C. Platelet activation in obese women: role of inflammation and oxidant stress. J. Am. Med. Assoc. 288 (2002) 2008-2014
17. Guagnano M.T., Ferroni P., Santilli F., Paoletti V., Manigrasso M.R., Pescara L., Cuccurullo C., Ciabattoni G., and Davi G. Determinants of platelet activation in hypertensives with microalbuminuria. Free Radic. Biol. Med. 46 (2009) 922-927
18. Suzuki N., Hishinuma T., Chiba S., Saga T., Tsukamoto H., Mizugaki M., and Goto J. Quantitative liquid chromatography-tandem mass spectrometric analysis of 11-dehydro TXB2 in urine. Prostaglandins Other Lipid Mediat. 73 (2004) 103-110
19. Taylor A.W., Bruno R.S., Frei B., and Traber M.G. Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes. Anal. Biochem. 350 (2006) 41-51
20. Takabatake M., Hishinuma T., Suzuki N., Chiba S., Tsukamoto H., Nakamura H., Saga T., Tomioka Y., Kurose A., Sawai T., and Mizugaki M. Simultaneous quantification of prostaglandins in human synovial cell-cultured medium using liquid chromatography/tandem mass spectrometry. Prostaglandins Leukot. Essent. Fatty Acids 67 (2002) 51-56
21. Sircar D., and Subbaiah P.V. Isoprostane measurement in plasma and urine by liquid chromatography-mass spectrometry with one-step sample preparation. Clin. Chem. 53 (2007) 251-258
22. Yan W., Byrd G.D., and Ogden M.W. Quantitation of isoprostane isomers in human urine from smokers and nonsmokers by LC-MS/MS. J. Lipid Res. 48 (2007) 1607-1617
23. Griffiths H.R., Moller L., Bartosz G., Bast A., Bertoni-Freddari C., Collins A., Cooke M., Coolen S., Haenen G., Hoberg A.M., Loft S., Lunec J., Olinski R., Parry J., Pompella A., Poulsen H., Verhagen H., and Astley S.B. Biomarkers. Mol. Aspects Med. 23 (2002) 101-208
24. Milne G.L., Sanchez S.C., Musiek E.S., and Morrow J.D. Quantification of F2-isoprostanes as a biomarker of oxidative stress. Nat. Protoc. 2 (2007) 221-226
25. Cracowski J.L., Bonaz B., Bessard G., Bessard J., Anglade C., and Fournet J. Increased urinary F2-isoprostanes in patients with Crohn's disease. Am. J. Gastroenterol. 97 (2002) 99-103
26. Bachi A., Zuccato E., Baraldi M., Fanelli R., and Chiabrando C. Measurement of urinary 8-Epi-prostaglandin F2alpha, a novel index of lipid peroxidation in vivo, by immunoaffinity extraction/gas chromatography-mass spectrometry. Basal levels in smokers and nonsmokers. Free Radic. Biol. Med. 20 (1996) 619-624
27. Schweer H., Meese C.O., Furst O., Kuhl P.G., and Seyberth H.W. Tandem mass spectrometric determination of 11-dehydrothromboxane B2, an index metabolite of thromboxane B2 in plasma and urine. Anal. Biochem. 164 (1987) 156-163
28. Morrow J.D., and Minton T.A. Improved assay for the quantification of 11-dehydrothromboxane B2 by gas chromatography-mass spectrometry. J. Chromatogr. 612 (1993) 179-185
29. Saenger A.K., Laha T.J., Edenfield M.J., and Sadrzadeh S.M. Quantification of urinary 8-iso-PGF2alpha using liquid chromatography-tandem mass spectrometry and association with elevated troponin levels. Clin. Biochem. 40 (2007) 1297-1304
30. Shishehbor M.H., Zhang R., Medina H., Brennan M.L., Brennan D.M., Ellis S.G., Topol E.J., and Hazen S.L. Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease. Free Radic. Biol. Med. 41 (2006) 1678-1683
31. Cavalca V., Sisillo E., Veglia F., Tremoli E., Cighetti G., Salvi L., Sola A., Mussoni L., Biglioli P., Folco G., Sala A., and Parolari A. Isoprostanes and oxidative stress in off-pump and on-pump coronary bypass surgery. Ann. Thorac. Surg. 81 (2006) 562-567
32. Tang M., Cyrus T., Yao Y., Vocun L., and Pratico D. Involvement of thromboxane receptor in the proatherogenic effect of isoprostane F2alpha-III: evidence from apolipoprotein E- and LDL receptor-deficient mice. Circulation 112 (2005) 2867-2874