Lycorine reduces mortality of human enterovirus 71-infected mice by inhibiting virus replication

Virology Journal

Volumn 8, Issue , 2011, Pages

  Liu, Jiangning ^a   Yang, Yajun ^a   Xu, Yanfeng ^b   Ma, Chunmei ^b   Qin, Chuan ^a,b   Zhang, Lianfeng ^a,b  

^a BEIJING HOSPITAL   (China)

^b State Administration of Traditional Chinese Medicine   (China)

Author keywords

Drug; Human enterovirus 71; Lycorine; Mouse model

Indexed keywords

LYCORINE; PLACEBO; RIBAVIRIN; VIRUS PROTEIN; AMARYLLIDACEAE ALKALOID; ANTIVIRUS AGENT; PHENANTHRIDINE DERIVATIVE; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG EFFICACY; ENTEROVIRUS 71; ENTEROVIRUS 71 INFECTION; ENTEROVIRUS INFECTION; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOLOGY; LETHAL DOSE; MORTALITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARALYSIS; PROTEIN SYNTHESIS; RHABDOMYOSARCOMA; SCORING SYSTEM; SURVIVAL RATE; SURVIVAL TIME; TRANSLATION INITIATION; VIRION; VIRUS INHIBITION; VIRUS LOAD; VIRUS REPLICATION; ANIMAL; DNA SEQUENCE; DRUG EFFECT; ENTEROVIRUS; GENETICS; HOSPITALIZATION; INSTITUTE FOR CANCER RESEARCH MOUSE; MOLECULAR GENETICS; PATHOLOGY; SURVIVAL; TUMOR CELL LINE;

HUMAN ENTEROVIRUS 71; MUS;

AMARYLLIDACEAE ALKALOIDS; ANIMALS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CYTOPATHOGENIC EFFECT, VIRAL; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; HUMANS; MICE; MICE, INBRED ICR; MOLECULAR SEQUENCE DATA; PARALYSIS; PHENANTHRIDINES; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; VIRUS REPLICATION;

EID: 80054936043     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-8-483     Document Type: Article

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