Enhancement of in vitro and in vivo anticancer activities of polysaccharide peptide from Grifola frondosa by chemical modifications

Pharmaceutical Biology

Volumn 49, Issue 11, 2011, Pages 1114-1120

  Chan, Janet Yuen Yan ^a   Chan, Enoch ^a   Chan, Shun Wan ^a,b   Sze, Shun Yin ^a   Chan, Ming Fai ^a   Tsui, Siu Hung ^a   Leung, Kit Yee ^a   Chan, Robbie Yat Kan ^a   Chung, Ivan Ying Ming ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

Author keywords

Adjuvant effect; Brain cells; C6; Cyclophosphamide; Edible mushroom; Maitake; Rat

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; POLYSACCHARIDE PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG MECHANISM; GLIOMA; GRIFOLA; GRIFOLA FRONDOSA; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOSIS INHIBITION; NONHUMAN; RAT;

ACETYLATION; ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ESTERIFICATION; GLIOMA; GRIFOLA; MALE; MOLECULAR STRUCTURE; PHOSPHORYLATION; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

BASIDIOMYCOTA; GRIFOLA FRONDOSA; POLYPORACEAE; RATTUS;

EID: 80054922140     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2011.569557     Document Type: Article

References (34)

1. Cavalli F, Hansen HH, Kaye SB. (2004). Textbook of Medical Oncology. London, UK: Taylor & Francis Group.
2. Chan SL, Yeung JH. (2006). Effects of polysaccharide peptide (PSP) from Coriolus versicolor on the pharmacokinetics of cyclophosphamide in the rat and cytotoxicity in HepG2 cells. Food Chem Toxicol, 44, 689-694.
3. Committee to Revise the Guide, Institute of Laboratory Animal Resources Council, Commission on Life Sciences, National Research Council. (1996). Guide for the Care and Use of Laboratory Animals. 7th edn. Washington, DC: National Academy Press.
4. Ooi VE, Liu F. (2000). Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Curr Med Chem, 7, 715-729.
5. Cui FJ, Li Y, Xu YY, Liu ZQ, Huang DM, Zhang ZC, Tao WY. (2007a). Induction of apoptosis in SGC-7901 cells by polysaccharidepeptide GFPS1b from the cultured mycelia of Grifola frondosa GF9801. Toxicol in vitro, 21, 417-427.
6. Cui FJ, Li Y, Xu ZH, Xu HY, Sun K, Tao WY. (2006). Optimization of the medium composition for production of mycelial biomass and exo-polymer by Grifola frondosa GF9801 using response surface methodology. Bioresour Technol, 97, 1209-1216.
7. Cui FJ, Tao WY, Xu ZH, Guo WJ, Xu HY, Ao ZH, Jin J, Wei YQ. (2007b). Structural analysis of anti-tumor heteropolysaccharide GFPS1b from the cultured mycelia of Grifola frondosa GF9801. Bioresour Technol, 98, 395-401.
8. Fan G, Filipczak L, Chow E. (2007). Symptom clusters in cancer patients: A review of the literature. Curr Oncol, 14, 173-179.
9. Gordon JS, Curtin S. (2000). Comprehensive cancer care: Integrating alternative, complementary, and conventional therapies. J Natl Cancer Inst, 92, 1945-1946.
10. Gorter JA, Aronica E, Hack NJ, Balázs R, Wadman WJ. (1995). Development of voltage-activated potassium currents in cultured cerebellar granule neurons under different growth conditions. J Neurophysiol, 74, 298-306.
11. Gu CQ, Li J, Li JW, Chao FH. (2006). Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-alpha in HepG2 2.2.15. Antiviral Res, 72, 162-165.
12. Hattori TS, Komatsu N, Shichijo S, Itoh K. (2004). Protein-bound polysaccharide K induced apoptosis of the human Burkitt lymphoma cell line, Namalwa. Biomed Pharmacother, 58, 226-230.
13. Inoue K, Kawamoto K, Nakajima H, Kohno M, Kadoya S, Mizuno D. (1983). Chemical modification and antitumor activity of a D-manno-D-glucan from Microellobosporia grisea. Carbohydr Res, 115, 199-208.
14. Jiménez-Medina E, Berruguilla E, Romero I, Algarra I, Collado A, Garrido F, Garcia-Lora A. (2008). The immunomodulator PSK induces in vitro cytotoxic activity in tumour cell lines via arrest of cell cycle and induction of apoptosis. BMC Cancer, 8, 78.
15. Kwilosz D, Koroukian S, OToole E, Smyth K, Townsend A, VonGruenigen V, Rose J. (2007). Psychosocial registry for persons with cancer: A method of facilitating quality of life and symptom research. Psychooncology, 16, 358-364.
16. Lavi I, Friesem D, Geresh S, Hadar Y, Schwartz B. (2006). An aqueous polysaccharide extract from the edible mushroom Pleurotus ostreatus induces anti-proliferative and pro-apoptotic effects on HT-29 colon cancer cells. Cancer Lett, 244, 61-70.
17. Lee BC, Bae JT, Pyo HB, Choe TB, Kim SW, Hwang HJ, Yun JW. (2003). Biological activities of the polysaccharides produced from submerged culture of the edible basidiomycete Grifola frondosa. Enzyme Microb Tech, 32, 574-581.
18. Lee JC, Lee KY, Son YO, Choi KC, Kim J, Truong TT, Jang YS. (2005). Plant-originated glycoprotein, G-120, inhibits the growth of MCF-7 cells and induces their apoptosis. Food Chem Toxicol, 43, 961-968.
19. Li G, Kim DH, Kim TD, Park BJ, Park HD, Park JI, Na MK, Kim HC, Hong ND, Lim K, Hwang BD, Yoon WH. (2004). Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells. Cancer Lett, 216, 175-181.
20. Li WY, Chan SW, Guo DJ, Chung MK, Leung TY, Yu PH. (2009). Water extract of Rheum officinale Baill. induces apoptosis in human lung adenocarcinoma A549 and human breast cancer MCF-7 cell lines. J Ethnopharmacol, 124, 251-256.
21. Liu JX, Zhou JY, Liu TF. (1999). Phase III clinical trial for the Yun Zhi polysaccharide (PSP) capsules. In Advanced Research in PSP 1999, ed. QY Yang, pp. 295-303. Hong Kong: The Hong Kong Association for Health Care Limited.
22. Mayell M. (2001). Maitake extracts and their therapeutic potential. Altern Med Rev, 6, 48-60.
23. Mei YA, Wu MM, Huan CL, Sun JT, Zhou HQ, Zhang ZH. (2000). 4-aminopyridine, a specific blocker of K+ channels, inhibited inward Na+ current in rat cerebellar granule cells. Brain Res, 873, 46-53.
24. Nanba H. (1995). Activity of maitake D-fraction to inhibit carcinogenesis and metastasis. Ann N Y Acad Sci, 768, 243-245.
25. Newton HB. (2002). Chemotherapy for the treatment of metastatic brain tumors. Expert Rev Anticancer Ther, 2, 495-506.
26. Ohno N, Iino K, Takeyama T, Suzuki I, Sato K, Oikawa S, Miyazaki T, Yadomae T. (1985). Structural characterization and antitumor activity of the extracts from matted mycelium of cultured Grifola frondosa. Chem Pharm Bull, 33, 3395-3401.
27. Qian ZM, Xu MF, Tang PL. (1997). Polysaccharide peptide (PSP) restores immunosuppression induced by cyclophosphamide in rats. Am J Chin Med, 25, 27-35.
28. Schuette W. (2001). Chemotherapy as treatment of primary and recurrent small cell lung cancer. Lung Cancer, 33 Suppl 1, S99-107.
29. Stamets P. (2000). Growing Gourmet and Medicinal Mushrooms. Berkeley, California: Ten Speed Press.
30. Suzuki I, Itani T, Ohno N, Oikawa S, Sato K, Miyazaki T, Yadomae T. (1984). Antitumor activity of a polysaccharide fraction extracted from cultured fruiting bodies of Grifola frondosa. J Pharmacobio- Dyn, 7, 492-500.
31. Tewarson SL, Mittal VP, Singh M, Gupta GP. (1993). Serum sialic acid-an important cancer marker. Indian J Cancer, 30, 125-131.
32. Tseng SH, Hwang LH, Lin SM. (1997). Induction of antitumor immunity by intracerebrally implanted rat C6 glioma cells genetically engineered to secrete cytokines. J Immunother, 20, 334-342.
33. Yang X, Sit WH, Chan DK, Wan JM. (2005). The cell death process of the anticancer agent polysaccharide-peptide (PSP) in human promyelocytic leukemic HL-60 cells. Oncol Rep, 13, 1201-1210.
34. Zhang M, Cui SW, Cheung PCK, Wang Q. (2007). Antitumor polysaccharides from mushrooms: A review on their isolation process, structural characteristics and antitumor activity. Trends Food Sci Tech, 18, 4-19.