Elevated expression of activation-induced cytidine deaminase in T and NK cells from patients with chronic active Epstein-Barr virus infection

European Journal of Dermatology

Volumn 21, Issue 5, 2011, Pages 780-782

  Nakamura, Motonobu ^a   Iwata, Seiko ^b   Kimura, Hiroshi ^b   Tokura, Yoshiki ^c  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD56 ANTIGEN; CD94 ANTIGEN; CYTIDINE DEAMINASE; MESSENGER RNA; SMALL NUCLEAR RNA;

ADULT; ARTICLE; CASE REPORT; CHRONIC DISEASE; CLINICAL ASSESSMENT; DISEASE SEVERITY; ENZYME ACTIVATION; EPSTEIN BARR VIRUS INFECTION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTOSIS; MALE; NATURAL KILLER CELL; PROTEIN EXPRESSION; SKIN BIOPSY; SKIN NECROSIS; T LYMPHOCYTE; VESICULAR RASH; VIRUS CELL INTERACTION;

ADOLESCENT; ADULT; CHILD; CHRONIC DISEASE; CYTIDINE DEAMINASE; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; RNA PROCESSING, POST-TRANSCRIPTIONAL; YOUNG ADULT;

EID: 80054918920     PISSN: 11671122     EISSN: 19524013     Source Type: Journal    
DOI: 10.1684/ejd.2011.1433     Document Type: Article

References (6)

1. Kimura H. Pathogenesis of chronic active Epstein-Barr virus infection: is this an infectious disease, lymphoproliferative disorder, or immunodeficiency? Rev Med Virol 2006; 16: 251-61.
2. Tokura Y, Ishihara S, Tagawa S, et al. Hypersensitivity to mosquito bites as the primary clinical manifestation of a juvenile type of Epstein-Barr virus-associated natural killer cell leukemia/lymphoma. J Am Acad Dermatol 2001; 45: 569-78.
3. Iwata S, Wada K, Tobita S, et al. Quantitative analysis of Epstein- Barr virus (EBV)-related gene expression in patients with chronic active EBV infection. J Gen Virol 2010; 91: 42-50.
4. Honjo T, Kinoshita K, Muramatsu M. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Anuu Rev Immunol 2002; 20: 165-96.
5. Matsumoto Y, Marusawa H, Kinoshita K, et al. Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat Med 2007; 13: 470-6.
6. Nakamura M, Sugita K, Sawada Y, et al. High levels of AID expression in adult T-cell leukemia/lymphoma. Br J Dermatol 2011 (in press).