A simple and efficient metal-free synthesis of tetrasubstituted pyrroles by iodine-catalyzed four-component coupling reaction of aldehydes, amines, dialkyl acetylenedicarboxylates, and nitromethane

Synthesis

Volumn , Issue 21, 2011, Pages 3471-3474

  Das, Biswanath ^a   Bhunia, Nisith ^a   Lingaiah, Maram ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

1,2,3,4 tetrasubstituted pyrroles; four component coupling reaction; iodine; metal free synthesis

Indexed keywords

1,2,3,4-TETRASUBSTITUTED PYRROLES; COUPLING REACTION; DIALKYL ACETYLENEDICARBOXYLATES; FOUR-COMPONENT COUPLING REACTION; HIGH YIELD; METAL-FREE SYNTHESIS; MOLECULAR IODINE; NITROMETHANE;

ALDEHYDES; AMINES; INDUSTRIAL CHEMICALS; IODINE;

SYNTHESIS (CHEMICAL);

ALDEHYDE; AMINE DERIVATIVE; DIALKYL ACETYLENEDICARBOXYLIC ACID DERIVATIVE; DICARBOXYLIC ACID DERIVATIVE; DIETHYL 1,4 DIPHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 1 (4 BROMOMETHYL) 4 PHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 1 BENZYL 4 (3,4 DIMETHOXYPHENYL) 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 1 PHENYL 4 (3,4,5 TRIMETHOXYPHENYL) 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 1 PHENYL 4 (THIOPHEN 2 YL) 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 1 PHENYL 4 4 TOLYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 4 (2 NITROPHENYL) 1 PHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 4 (3,4 DIMETHOXYPHENYL) 1 PHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 4 (4 BROMOPHENYL) 1 PHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 4 (4 CHLOROPHENYL) 1 PHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 4 (4 FLUOROPHENYL) 1 PHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 4 (4 METHOXYPHENYL) 1 PHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; DIMETHYL 4 (4 NITROPHENYL) 1 PHENYL 1H PYRROLE 2,3 DICARBOXYLIC ACID; IODINE; NITROMETHANE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CATALYST; CHEMICAL REACTION; CHEMICAL STRUCTURE; CROSS COUPLING REACTION; ELECTROSPRAY MASS SPECTROMETRY; INFRARED RADIATION; MICHAEL ADDITION; PROCESS OPTIMIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

EID: 80054899734     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260228     Document Type: Article

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