Miniaturized chromatographic system for determination of coenzyme Q10 in plasma, muscle and platelets;Sistema cromatográfico miniaturizado para la determinación de coenzima Q10 en plasma, músculo y plaquetas

Acta Bioquimica Clinica Latinoamericana

Volumn 45, Issue 2, 2011, Pages 273-278

  Contin, Mario ^a,b   Martinefski, Manuela ^a   Lucangioli, Silvia ^a,b   Tripodi, Valeria ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b CONICET ^*  (Argentina)

Author keywords

Coenzyme Q10; Miniaturized chromatographic analytical system; Muscle; Plasma; Platelets

Indexed keywords

EID: 80054882589     PISSN: 03252957     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Barshop B, Gangoiti J. Analysis of coenzyme Q in human blood and tissues. Mitochondrion S7 2007; S89-S93. (Pubitemid 46712241)
2. Crane F. Biochemical functions of coenzyme Q10. J Am Coll Nutr 2000; 20 (6): 591-8.
3. Ernster L, Dallner G. Biochemical, physiological and medical aspects of ubiquinone function. Biochim Biophys Acta 1995; 1271: 195-204.
4. Teran E, Hernandez I, Nieto B, Tavara R, Ocampo J, Ca-lle A. Coenzyme Q10 suplementation during pregnancy reduces the risk of pre-eclampsia. Int J Gyneacol Obstet 2009; 105: 43-5.
5. Matthews R, Yang L, Browne S, Baik M, Beal, MF. Co-enzyme Q10 administration increases brain mitochon-drial concentration and exerts neuroprotective effects. Proc Natl Acad Sci USA 1998; 95: 8892-7.
6. Shults C, Oakes D, Kieburtz K, Beal M, Haas R, Plumb S, et al. Effects of coenzyme Q10 in early Parkinson disease. Arch Neurol 2002; 59: 1541-50.
7. Molyneux S, Young J, Florkowski C, Lever M. Coenzyme Q10: is there a clinical role and a case for measurement? Clin Biochem Rev 2008; 29 (2); 71-82.
8. Kaplan P, Sebestianová N, Turiaková J, Kučera I. Determination of coenzyme Q in human plasma. Physiol Res 1996; 45 (1): 39-45. (Pubitemid 26088894)
9. Niklowitz P, Menke T, Andler W, Okun J. Simultaneous analysis of coenzyme Q10 in plasma, erythrocytes and platelets: comparison of the antioxidant level in blood cells and their environment in healthy children and after oral supplementation in adults. Clin Chim Acta 2004; 342: 219-26. (Pubitemid 38352932)
10. Hansen G, Christensen P, Tüchsen E,Lund T. Sensitive and selective analysis of coenzyme Q10 in human serum by negative APCI LC-MS. Analyst 2004; 129: 45-50. (Pubitemid 38130300)
11. Grossi G, Bargossi A, Fiorella P, Piazzi S.Improved highperformance liquid chromatographic method for the determination of coenzyme Q10 in plasma. J Chromatogr 1992; 593: 217-26.
12. Asensio Ramos M, Hernández Borges J, Rocco A, Fanali S. Food analysis: A continuous challenge for miniaturized separation techniques. J Sep Sci 2009; 32(24): 3764-800.
13. Tripodi V, Flor S, Contin M, Lucangioli S. Simple, highly sensitive micro HPLC method for the determination of coenzyme Q10 and its major related substances. J Liq Chromatogr Relat Technol 2009; 32: 1-14.
14. U.S. Department of Health and Human Services Food and Drug Administration (FDA). Guidance for Industry Bioanalytical Method Validation. Disponible en: http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/ Guidances/ucm070107.pdf (Fecha de acceso 1 de mayo de 2001).
15. Gopta O, Semenov A, Bloch D. Electrogenic proton transfer in Rhodobacter sphaeroides reaction centers: effect of coenzyme Q10 substitution by decylubiquinone in the CB binding site. FEBS Lett 2001; 499: 116-20. (Pubitemid 32539333)
16. Miles M, Tang P, Miles L, Steele, P, Moye M, Horn P. Validation and application of an HPLC-EC method for analysis of coenzyme Q10 in blood platelets. Biomed Chromatogr 2008; 22: 1403-8.