Trichostatin A inhibits expression of cathepsins in experimental osteoarthritis

Rheumatology International

Volumn 31, Issue 10, 2011, Pages 1325-1331

  Chen, Wei Ping ^a   Bao, Jia Peng ^a   Tang, Jin Li ^a   Hu, Peng Fei ^a   Wu, Li Dong ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

ACLT; Cathepsins; Cystatin C; Osteoarthritis; Trichostatin A

Indexed keywords

CATHEPSIN; CATHEPSIN B; CATHEPSIN K; CATHEPSIN L; CATHEPSIN S; CYSTATIN C; DIMETHYL SULFOXIDE; MESSENGER RNA; TRICHOSTATIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; CARTILAGE; CONTROLLED STUDY; EXPERIMENTAL RABBIT; GENE EXPRESSION; HISTOPATHOLOGY; KNEE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TREATMENT DURATION;

ANIMALS; CATHEPSINS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROXAMIC ACIDS; MALE; OSTEOARTHRITIS, KNEE; PROTEASE INHIBITORS; RABBITS;

EID: 80054880695     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-010-1481-7     Document Type: Article

References (35)

1. MD Tortorella AM Malfait C Deccico E Arner 2001 The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation Osteoarthr Cartil 9 539 552 11520168 10.1053/joca.2001.0427 1:STN:280:DC%2BD3MvnslGmug%3D%3D (Pubitemid 32842633)
2. PS Burrage KS Mix CE Brinckerhoff 2006 Matrix metalloproteinases: role in arthritis Front Biosci 11 529 543 16146751 10.2741/1817 1:CAS:528: DC%2BD2MXhtlSrurrE (Pubitemid 43258162)
3. Y Yasuda J Kaleta D Bromme 2005 The role of cathepsins in osteoporosis and arthritis: rationale for the design of new therapeutics Adv Drug Deliv Rev 57 973 993 15876399 10.1016/j.addr.2004.12.013 1:CAS:528:DC%2BD2MXjvVKmsr8%3D (Pubitemid 40703885)
4. RA Dodds JR Connor FH Drake M Gowen 1999 Expression of cathepsin K messenger RNA in giant cells and their precursors in human osteoarthritic synovial tissues Arthritis Rheum 42 1588 1593 10446855 10.1002/1529-0131(199908) 42:8<1588::AID-ANR4>3.0.CO;2-S 1:CAS:528:DyaK1MXlsFynsbg%3D (Pubitemid 30263624)
5. HJ Salminen-Mankonen J Morko E Vuorio 2007 Role of cathepsin K in normal joints and in the development of arthritis Curr Drug Targets 8 315 323 17305509 10.2174/138945007779940188 1:CAS:528:DC%2BD2sXhs1ygsro%3D
6. VM Dejica JS Mort S Laverty MD Percival J Antoniou DJ Zukor, et al. 2008 Cleavage of type II collagen by cathepsin K in human osteoarthritic cartilage Am J Pathol 173 161 169 18511517 10.2353/ajpath.2008.070494 1:CAS:528: DC%2BD1cXptVGqu78%3D (Pubitemid 351947964)
7. JP Morko M Soderstrom AM Saamanen HJ Salminen EI Vuorio 2004 Up regulation of cathepsin K expression in articular chondrocytes in a transgenic mouse model for osteoarthritis Ann Rheum Dis 63 649 655 15140771 10.1136/ard.2002.004671 1:CAS:528:DC%2BD2cXltFekurg%3D (Pubitemid 38658393)
8. A Baici A Lang R Zwicky K Muntener 2005 Cathepsin B in osteoarthritis: uncontrolled proteolysis in the wrong place Semin Arthritis Rheum 34 Suppl 2 24 28 16206953 1:CAS:528:DC%2BD2MXntVSjsLw%3D (Pubitemid 44302002)
9. S Petanceska P Canoll LA Devi 1996 Expression of rat cathepsin S in phagocytic cells J Biol Chem 271 4403 4409 8626791 10.1074/jbc.271.8.4403 1:CAS:528:DyaK28XhtlSmtLc%3D (Pubitemid 26070548)
10. Q Nguyen JS Mort PJ Roughley 1990 Cartilage proteoglycan aggregate is degraded more extensively by cathepsin L than by cathepsin B Biochem J 266 569 573 2317204 1:STN:280:DyaK3c7pslKguw%3D%3D (Pubitemid 20090162)
11. A Lang D Horler A Baici 2000 The relative importance of cysteine peptidases in osteoarthritis J Rheumatol 27 1970 1979 10955340 1:CAS:528:DC%2BD3cXlvFeltro%3D (Pubitemid 30670490)
12. J Martel-Pelletier JM Cloutier JP Pelletier 1990 Cathepsin B and cysteine protease inhibitors in human osteoarthritis J Orthop Res 8 336 344 2324852 10.1002/jor.1100080305 1:STN:280:DyaK3c3hvVCksQ%3D%3D (Pubitemid 20250856)
13. JR Connor C Lepage BA Swift D Yamashita AM Bendele D Maul, et al. 2009 Protective effects of a cathepsin K inhibitor, SB-553484, in the canine partial medial meniscectomy model of osteoarthritis Osteoarthr Cartil 17 1236 1243 19361586 10.1016/j.joca.2009.03.015 1:STN:280:DC%2BD1MrntVSitQ%3D%3D
14. L Svelander H Erlandsson-Harris L Astner U Grabowska L Klareskog E Lindstrom, et al. 2009 Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice Eur J Pharmacol 613 155 162 19358841 10.1016/j.ejphar.2009.03.074 1:CAS:528:DC%2BD1MXms1yisL4%3D
15. R Piekarz S Bates 2004 A review of depsipeptide and other histone deacetylase inhibitors in clinical trials Curr Pharm Des 10 2289 2298 15279609 10.2174/1381612043383980 1:CAS:528:DC%2BD2cXltFCntrc%3D (Pubitemid 38855037)
16. N Chabane N Zayed H Afif L Mfuna-Endam M Benderdour C Boileau, et al. 2008 Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes Osteoarthr Cartil 16 1267 1274 18417374 10.1016/j.joca.2008.03.009 1:STN:280:DC%2BD1crpslartA%3D%3D
17. Y Choi SK Park HM Kim JS Kang YD Yoon SB Han, et al. 2008 Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model Exp Mol Med 40 574 581 18985016 10.3858/emm.2008.40.5.574 1:CAS:528:DC%2BD1cXhtlOgtb%2FP (Pubitemid 352789098)
18. DA Young RL Lakey CJ Pennington D Jones L Kevorkian DR Edwards, et al. 2005 Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption Arthritis Res Ther 7 R503 R512 15899037 10.1186/ar1702 1:CAS:528:DC%2BD2MXivVygsLc%3D
19. Y Nasu K Nishida S Miyazawa T Komiyama Y Kadota N Abe, et al. 2008 Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model Osteoarthr Cartil 16 723 732 18226559 10.1016/j.joca.2007.10.014 1:STN:280:DC%2BD1czmsFOhsg%3D%3D
20. HS Lin CY Hu HY Chan YY Liew HP Huang L Lepescheux, et al. 2007 Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents Br J Pharmacol 150 862 872 17325656 10.1038/sj.bjp.0707165 1:CAS:528:DC%2BD2sXjs12nt7c%3D (Pubitemid 46536628)
21. JP Bao WP Chen J Feng J Zhao ZL Shi K Huang, et al. 2009 Variation patterns of two degradation enzyme systems in articular cartilage in different stages of osteoarthritis: Regulation by dehydroepiandrosterone Clin Chim Acta 408 1 7 19589338 10.1016/j.cca.2009.06.040 1:CAS:528:DC%2BD1MXhtFamsL%2FP
22. H Jo HJ Ahn EM Kim HJ Kim SC Seong I Lee, et al. 2004 Effects of dehydroepiandrosterone on articular cartilage during the development of osteoarthritis Arthritis Rheum 50 2531 2538 15334467 10.1002/art.20368 1:CAS:528:DC%2BD2cXnsVKht78%3D (Pubitemid 39062714)
23. AR Shikhman D Amiel D D'Lima SB Hwang C Hu A Xu, et al. 2005 Chondroprotective activity of N-acetylglucosamine in rabbits with experimental osteoarthritis Ann Rheum Dis 64 89 94 15608304 10.1136/ard.2003.019406 1:CAS:528:DC%2BD2MXptVakuw%3D%3D (Pubitemid 40075281)
24. KP Pritzker S Gay SA Jimenez K Ostergaard JP Pelletier PA Revell, et al. 2006 Osteoarthritis cartilage histopathology: grading and staging Osteoarthr Cartil 14 13 29 16242352 10.1016/j.joca.2005.07.014 1:STN:280: DC%2BD28%2FhsVWrsg%3D%3D (Pubitemid 43034086)
25. W Kafienah D Bromme DJ Buttle LJ Croucher AP Hollander 1998 Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix Biochem J 331 727 732 9560298 1:CAS:528:DyaK1cXjt12iu7s%3D (Pubitemid 28211893)
26. MC Burleigh AJ Barrett GS Lazarus 1974 Cathepsin B1. A lysosomal enzyme that degrades native collagen Biochem J 137 387 398 4207388 1:CAS:528: DyaE2cXktVSktbw%3D
27. WS Hou Z Li FH Buttner E Bartnik D Bromme 2003 Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation Biol Chem 384 891 897 12887056 10.1515/BC.2003.100 1:CAS:528: DC%2BD3sXlslGnsbY%3D (Pubitemid 36874503)
28. S Kamolmatyakul W Chen S Yang Y Abe R Moroi AM Ashique, et al. 2004 IL-1alpha stimulates cathepsin K expression in osteoclasts via the tyrosine kinase-NF-kappaB pathway J Dent Res 83 791 796 15381721 10.1177/ 154405910408301011 1:CAS:528:DC%2BD2cXptFKisb4%3D (Pubitemid 41766161)
29. A Ruettger S Schueler JA Mollenhauer B Wiederanders 2008 Cathepsins B, K, and L are regulated by a defined collagen type II peptide via activation of classical protein kinase C and p38 MAP kinase in articular chondrocytes J Biol Chem 283 1043 1051 17991740 10.1074/jbc.M704915200 1:CAS:528: DC%2BD1cXhsFaktQ%3D%3D
30. R Kawaida T Ohtsuka J Okutsu T Takahashi Y Kadono H Oda, et al. 2003 Jun dimerization protein 2 (JDP2), a member of the AP-1 family of transcription factor, mediates osteoclast differentiation induced by RANKL J Exp Med 197 1029 1035 12707301 10.1084/jem.20021321 1:CAS:528:DC%2BD3sXjt1Wls78%3D (Pubitemid 36523200)
31. C Fabre J Grosjean M Tailler S Boehrer L Ades JL Perfettini, et al. 2008 A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts Cell Cycle 7 2139 2145 18641459 10.4161/cc.7.14.6268 1:CAS:528:DC%2BD1cXhtVykur3O (Pubitemid 352031516)
32. H Zhong MJ May E Jimi S Ghosh 2002 The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1 Mol Cell 9 625 636 11931769 10.1016/S1097-2765(02)00477-X 1:CAS:528:DC%2BD38XivVylt7k%3D (Pubitemid 34273792)
33. N Kawamata J Chen HP Koeffler 2007 Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells Blood 110 2667 2673 17606765 10.1182/blood-2005-11-026344 1:CAS:528: DC%2BD2sXhtFCnsbnP (Pubitemid 47523191)
34. Y Akasaki S Matsuda K Nakayama S Fukagawa H Miura Y Iwamoto 2009 Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation Osteoarthr Cartil 17 235 243 18672387 10.1016/j.joca.2008.06.012 1:STN:280:DC%2BD1M7itlWksA%3D%3D
35. YH Jean ZH Wen YC Chang SP Hsieh JD Lin CC Tang, et al. 2008 Increase in excitatory amino acid concentration and transporters expression in osteoarthritic knees of anterior cruciate ligament transected rabbits Osteoarthr Cartil 16 1442 1449 18524638 10.1016/j.joca.2008.04.008