Comparison of sedative effect of dexmedetomidine and midazolam for post-operative patients undergoing mechanical ventilation in surgical intensive care unit

Chinese Critical Care Medicine

Volumn 23, Issue 9, 2011, Pages 543-546

  Wan, Lin Jun ^a   Huang, Qing Qing ^a   Yue, Jin Xi ^a   Lin, Lan ^a   Li, Si Hong ^a  

^a KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Dexmedetomidine; Mechanical ventilation; Midazolam; Sedation; Side effect; Surgical intensive care unit

Indexed keywords

DEXMEDETOMIDINE; FENTANYL; LACTIC ACID; MIDAZOLAM;

ANALGESIA; ARTICLE; BLOOD GAS ANALYSIS; BLOOD PRESSURE MEASUREMENT; BRADYCARDIA; BREATHING RATE; CONTROLLED STUDY; DELIRIUM; ELECTROCARDIOGRAPHY; ENDOTRACHEAL INTUBATION; HUMAN; HYPOTENSION; INTENSIVE CARE; MAJOR CLINICAL STUDY; NAUSEA; OXYGEN SATURATION; POSTOPERATIVE CARE; SEDATION;

ADOLESCENT; ADULT; AGED; DEXMEDETOMIDINE; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; INTENSIVE CARE; INTENSIVE CARE UNITS; MALE; MIDAZOLAM; MIDDLE AGED; POSTOPERATIVE PERIOD; RESPIRATION, ARTIFICIAL; YOUNG ADULT;

EID: 80054867023     PISSN: 10030603     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.1003-0603.2011.09.007     Document Type: Article

References (14)

1. Jacobi J, Fraser GL, Coursin DB, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med, 2002,30:119-141. (Pubitemid 34112188)
2. Ostermann ME, Keenan SP, Seiferling RA, et al. Sedation in the intensive care unit: a systematic review. JAMA, 2000,283:1451-1459. (Pubitemid 30151824)
3. Herr DL, Sum-Ping ST, England M. ICU sedation after coronary artery bypass graft surgery: dexmedetomidine-based versus propofol-based sedation regimens. J Cardiothorac Vasc Anesth, 2003,17:576-584. (Pubitemid 37296621)
4. Triltsch AE, Welte M, von Homeyer P, et al. Bispectral index-guided sedation with dexmedetomidine in intensive care: a prospective, randomized, double blind, placebo-controlled phase II study. Crit Care Med, 2002,30:1007-1014. (Pubitemid 34508021)
5. Venn RM, Hell J, Grounds RM. Respiratory effects of dexmedetomidine in the surgical patient requiring intensive care. Crit Care, 2000,4:302-308.
6. Arain SR, Ruehlow RM, Uhrich TD, et al. The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg, 2004,98:153-158.
7. Kamibayashi T, Maze M. Clinical uses of alpha2-adrenergic agonists. Anesthesiology, 2000,93:1345-1349.
8. Maze M, Scarfini C, Cavaliere F. New agents for sedation in the intensive care unit. Crit Care Clin, 2001,17:881-897. (Pubitemid 33101686)
9. Ingersoll-Weng E, Manecke GR Jr, Thistlethwaite PA. Dexmedetomidine and cardiac arrest. Anesthesiology, 2004,100:738-739. (Pubitemid 38268898)
10. Maldonado JR, Wysong A, van der Starre PJ, et al. Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. Psychosomatics, 2009,50:206-217.
11. Riker RR, Shehabi Y, Bokesch PM, et al. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA, 2009,301:489-499.
12. Ray T, Tobias JD. Dexmedetomidine for sedation during electroencephalographic analysis in children with autism, pervasive developmental disorders, and seizure disorders. J Clin Anesth, 2008,20:364-368.