Effect of pulse frequency on the osteogenic differentiation of mesenchymal stem cells in a pulsatile perfusion bioreactor

Journal of Biomechanical Engineering

Volumn 133, Issue 9, 2011, Pages

  Kavlock, Katherine D ^a   Goldstein, Aaron S ^b  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b State University   (United States)

Author keywords

alkaline phosphatase; mesenchymal stem cells; osteopontin; PGE 2; PLGA; pulsatile perfusion

Indexed keywords

ALKALINE PHOSPHATASE; MESENCHYMAL STEM CELL; OSTEOPONTIN; PGE 2; PLGA; PULSATILE PERFUSION;

BIOREACTORS; BONE; FLOWCHARTING; OSTEOBLASTS; OXYGEN SUPPLY; PHOSPHATASES; PULSATILE FLOW; SCAFFOLDS (BIOLOGY); STEM CELLS; THREE DIMENSIONAL; TISSUE;

CELL CULTURE;

ALKALINE PHOSPHATASE; MESSENGER RNA; OSTEOPONTIN; PROSTAGLANDIN E2; TISSUE SCAFFOLD; LACTIC ACID; OSTEOCALCIN; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL CELL; ARTICLE; BIOREACTOR; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; MESENCHYMAL STEM CELL; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; PULSATILE PERFUSION BIOREACTOR; PULSE RATE; RAT; ANIMAL; BONE DEVELOPMENT; BONE MARROW CELL; CELL COUNT; CULTURE MEDIUM; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; METHODOLOGY; PULSATILE FLOW;

RATTUS;

ALKALINE PHOSPHATASE; ANIMALS; BIOREACTORS; BONE MARROW CELLS; CELL COUNT; CELL DIFFERENTIATION; CULTURE MEDIA, CONDITIONED; CULTURE TECHNIQUES; DINOPROSTONE; GENE EXPRESSION REGULATION; LACTIC ACID; MALE; MESENCHYMAL STEM CELLS; OSTEOCALCIN; OSTEOGENESIS; OSTEOPONTIN; POLYGLYCOLIC ACID; PULSATILE FLOW; RATS; RNA, MESSENGER; TISSUE SCAFFOLDS;

EID: 80054857002     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4004919     Document Type: Article

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