Temporal evaluation of effects of a model 3β-hydroxysteroid dehydrogenase inhibitor on endocrine function in the fathead minnow

Environmental Toxicology and Chemistry

Volumn 30, Issue 9, 2011, Pages 2094-2102

  Ankley, Gerald T ^a   Cavallin, Jenna E ^a   Durhan, Elizabeth J ^a   Jensen, Kathleen M ^a   Kahl, Michael D ^a   Makynen, Elizabeth A ^a   Martinovic Weigelt, Dalma ^a   Wehmas, Leah C ^a   Villeneuve, Daniel L ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Endocrine function; Fathead minnow; Reproduction; Steroidogenesis; Toxicity mechanisms

Indexed keywords

ACTIVE COMPENSATION; AROMATASE; DIRECT IMPACT; ENDOCRINE FUNCTIONS; FATHEAD MINNOW; FOLLICLE-STIMULATING HORMONE RECEPTORS; GENE PRODUCTS; HYDROXYSTEROID DEHYDROGENASE; PIMEPHALES PROMELAS; PLASMA CONCENTRATION; RECOVERY PHASE; REPRODUCTION; SEX STEROIDS; STEROIDOGENESIS; TEMPORAL EVALUATION; UP-REGULATION; VITELLOGENIN;

ANIMALS; ENZYME INHIBITION; GENE EXPRESSION; MICROARRAYS; RECOVERY;

GENE EXPRESSION REGULATION;

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; AROMATASE; ESTRADIOL; FOLLITROPIN RECEPTOR; GENE PRODUCT; SEX HORMONE; TRILOSTANE; VITELLOGENIN;

CONCENTRATION (COMPOSITION); CYPRINID; DRUG; ENDOCRINE DISRUPTOR; ENZYME ACTIVITY; ESTROGENIC COMPOUND; INHIBITION; INHIBITOR; PROTEIN; REPRODUCTIVE POTENTIAL; STEROID; TEMPORAL ANALYSIS; TOXICOLOGY;

ARTICLE; CONTROLLED STUDY; ENDOCRINE FUNCTION; ENZYME INHIBITION; ENZYME SYNTHESIS; FEMALE; GENE EXPRESSION; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; MALE; NONHUMAN; PIMEPHALES PROMELAS; PRIORITY JOURNAL; REPRODUCTION; REPRODUCTIVE TOXICITY; STEROIDOGENESIS; UPREGULATION;

17-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; AROMATASE; CYPRINIDAE; DIHYDROTESTOSTERONE; ENDOCRINE DISRUPTORS; ENDOCRINE SYSTEM; ENZYME INHIBITORS; ESTRADIOL; FEMALE; GENE EXPRESSION; GONADS; MALE; OVARY; RECEPTORS, FSH; REPRODUCTION; UP-REGULATION; VITELLOGENINS; WATER POLLUTANTS, CHEMICAL;

ANIMALIA; PIMEPHALES PROMELAS;

EID: 80054842970     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.593     Document Type: Article

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