Regime analysis of a Baeyer-Villiger bioconversion in a three-phase (air-water-ionic liquid) stirred tank bioreactor

Biochemical Engineering Journal

Volumn 58-59, Issue 1, 2011, Pages 87-95

  Melgarejo Torres, R ^a   Torres Martinez D ^a   Gutierrez Rojas M ^a   Gomez de Jesus A ^a   Lye, G J ^b   Huerta Ochoa, S ^a  

^a DEPARTAMENTO DE QUÍMICA   (Mexico)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Bioconversion; Ionic liquid; Mass transfer; Multiphase bioreactor; Oxygen transfer; Regime analysis

Indexed keywords

BAEYER-VILLIGER; BIOCONVERSION PROCESS; CHARACTERISTIC TIME; DIFFERENT MECHANISMS; DISPERSED PHASE; LIMITING STEP; MULTIPHASE BIOREACTOR; OPERATING CONDITION; OPERATIONAL CONDITIONS; OXYGEN TRANSFER; OXYGEN TRANSFER RATE; OXYGEN UPTAKE RATES; QUANTITATIVE ESTIMATES; REGIME ANALYSIS; STIRRED TANK BIOREACTORS;

AIR; BIOACTIVITY; BIOLOGICAL WATER TREATMENT; BIOREACTORS; IONIC LIQUIDS; IONS; MASS TRANSFER; OXYGEN; TANKS (CONTAINERS);

BIOCONVERSION;

IONIC LIQUID; OXYGEN; WATER;

AIR; ARTICLE; BAEYER VILLIGER REACTION; BIOTRANSFORMATION; CHEMICAL REACTION; CONTROLLED STUDY; DISPERSION; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN TRANSPORT; PRIORITY JOURNAL; STIRRED REACTOR;

EID: 80054839095     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2011.08.017     Document Type: Article

References (31)

1. Alphand V., Furstoss R. Microbiological transformations 44. Optimisation of a new Baeyer-Villigerase activity: application to the stereospecific oxidation of 3-phenylcyclobutanone. J. Mol. Catal. B: Enzym. 2000, 9:209-217.
2. Malito E., Alfieri A., Fraaije M.W., Mattevi A. Crystal structure of a Baeyer-Villiger monooxygenase. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:131576-213162.
3. Torres-Pazmiño D.E., Dudek H.M., Fraaije M.W. Baeyer-Villiger monooxygenases: recent advances and future challenges. Curr. Opin. Chem. Biol. 2010, 14:138-144.
4. Rodríguez C., de Gonzalo G., Fraaije M.W., Gotor V. Ionic liquids for enhancing the enantioselectivity of isolated BVMO-catalysed oxidations. Green Chem. 2010, 12:2255-2260.
5. Doig S.D., Avenell P.J., Bird P.A., Gallati P., Lander K.S., Lye G.J., Wohlgemuth R., Woodley J.M. Reactor operation and scale-up of whole cell Baeyer-Villiger catalyzed lactone synthesis. Biotechnol. Prog. 2002, 18:1039-1046.
6. Doo E.H., Lee W.H., Seo H.S., Seo J.H., Park J.B. Productivity of cyclohexanone oxidation of the recombinant Corynebacterium glutamicum expressing chnB of Acinetobacter calcoaceticus. J. Biotechnol. 2009, 142:164-169.
7. Malinowski J.J. Two-phase partitioning bioreactors in fermentation technology. Biotechnol. Adv. 2001, 19:525-538.
8. Pfruender H., Jones R., Weuster-Botz D. Water immiscible ionic liquids as solvents for whole cell biocatalysis. J. Biotechnol. 2006, 124:182-190.
9. Bräutigam S., Dennewald D., Schürmann M., Lutje-Spelberg J., Pitner W.R., Weuster-Botz D. Whole-cell biocatalysis: evaluation of new hydrophobic ionic liquids for efficient asymmetric reduction of prochiral ketones. Enzyme Microb. Technol. 2009, 45:310-316.
10. Cull S.G., Lovick J.W., Lye G.J., Angeli P. Scale-down studies on the hydrodynamic of two-liquid phase biocatalytic reactors. Bioproc. Biosyst. Eng. 2002, 14:3-153.
11. Sweere A.P.J., Luyben K.Ch.A.M., Kossen N.W.F. Regime analysis and scale-down: tools to investigate the performance bioreactors. Enzyme Microb. Technol. 1987, 9:386-398.
12. Luyben K.Ch.A.M. Regime analysis for the scale-down of biotechnological processes. Proceedings of Bioreactor Performance, Biotechnology Research Foundation 1993, Helsingor, Denmark, pp. 15-17/3. U. Mortensen, H. Noorman (Eds.).
13. Law H.E.M., Baldwin C.V.F., Chen B.H., Woodley J.M. Process limitations in a whole-cell catalysed oxidation: sensitivity analysis. Chem. Eng. Sci. 2006, 61:6646-6652.
14. Torres-Martínez D., Melgarejo-Torres R., Gutiérrez-Rojas M., Aguilera-Vázquez L., Micheletti M., Lye G.J., Huerta-Ochoa S. Hydrodynamic and oxygen mass transfer studies in a three-phase (air-water-ionic liquid) stirred tank bioreactor. Biochem. Eng. J. 2009, 45:209-217.
15. Skrzypczak A., Neta P. Diffusion-controlled electron-transfer reactions in ionic liquids. J. Phys. Chem. A 2003, 107:7800-7803.
16. Hadjiev D., Sabiri N.E., Zanati A. Mixing time in bioreactors under aerated conditions. Biochem. Eng. J. 2006, 27:323-330.
17. Lovick J., Mouza A.A., Paras S.V., Lye G.J., Angeli P. Drop size distribution in highly concentrated liquid-liquid systems in stirred tanks using a light back scattering method. J. Chem. Technol. Biotechnol. 2005, 80:545-552.
18. Maass S., Grünig J., Kraume M. Measurement techniques for drop size distribution in stirred liquid-liquid systems. Chem. Process Eng. 2009, 30:635-651.
19. La method. Biotechnol. Bioeng. 1984, 26:1131-1133.
20. La determination in fungal fermentation, taking into account electrode response time. J. Chem. Technol. Biotechnol. 2000, 75:469-474.
21. Bonvillani P., Ferrari M.P., Ducrós E.M., Orejas J.A. Theoretical and experimental study of the effects of scale-up on mixing time for a stirred-tank bioreactor. Braz. J. Chem. Eng. 2006, 23:1-7.
22. Al-Dahhan M., Wicks C.E. Modified contactor for experimental studies of mass transfer and chemical reaction across a liquid-liquid interface. Ind. Eng. Chem. Res. 1996, 35:3812-3816.
23. Srivastava P., Hahr O., Buchholz R., Worden R.M. Enhancement of mass transfer using colloidal liquid aphrons: measurement of mass transfer coefficients in liquid-liquid extraction. Biotechnol. Bioeng. 2000, 70:525-532.
24. Aldric J.M., Gillet S., Delvigne F., Blecker C., Lebeau F., Wathelet J., Manigat G., Thonart P. Effect of surfactants and biomass on the gas/liquid mass transfer in an aqueous-silicone oil two-phase partitioning bioreactor using Rhodococcus erythropolis T902.1 to remove VOCs from gaseous effluents. J. Chem. Technol. Biotechnol. 2009, 84:1274-1283.
25. Eibes G., McCann C., Pedezert A., Moreira M.T., Feijoo G., Lema J.M. Study of mass transfer and biocatalyst stability for the enzymatic degradation of anthracene in a two-phase partitioning bioreactor. Biochem. Eng. J. 2010, 51:79-85.
26. Quijano G., Huerta-Ochoa S., Gutiérrez-Rojas M. Assessment of the limiting step of mass transfer in n-hexadecane biodegradation in a bubble column reactor. Water Sci. Technol. 2010, 64:906-914.
27. Gomes N., Aguedo M., Teixeira J., Belo I. Oxygen mass transfer in a biphasic medium: influence on the biotransformation of methyl ricinoleate into (-decalactone by the yeast Yarrowia lipolytica. Biochem. Eng. J. 2007, 35:380-386.
28. Baldwin C., Woodley J. On oxygen limitation in a whole cell biocatalytic Baeyer-Villiger oxidation process. Biotechnol. Bioeng. 2006, 95:362-369.
29. Alphand V., Carrea G., Wohlgemuth R., Furstoss R., Woodley J.M. Toward large-scale synthetic applications of Baeyer-Villiger monooxygenases. Trends Biotechnol. 2003, 21:318-323.
30. Quijano G., Revah S., Gutiérrez-Rojas M., Flores-Cotera L.B., Thalasso F. Oxygen transfer in three-phase airlift and stirred tank reactors using silicone oil as transfer vector. Process Biochem. 2009, 44:619-624.
31. Anthony J.L., Anderson J.L., Maginn E.J., Brennecke J.F. Annion effects on gas solubility in ionic liquids. J. Phys. Chem. B 2005, 109:6366-6374.