Isotope-coded dimethyl tagging for differential quantification of posttranslational protein carbonylation by 4-hydroxy-2-nonenal, an end-product of lipid peroxidation

Journal of Mass Spectrometry

Volumn 46, Issue 10, 2011, Pages 976-985

  Rauniyar, Navin ^a,b   Prokai, Laszlo ^a  

^a UNIVERSITY OF NORTH TEXAS   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

4 hydroxy 2 nonenal; differential quantitative proteomics; LC MS MS; protein carbonylation; solid phase hydrazide chemistry; stable isotope tagging

Indexed keywords

4-HYDROXY-2-NONENAL; LC-MS/MS; PROTEIN CARBONYLATION; QUANTITATIVE PROTEOMICS; SOLID-PHASE; STABLE-ISOTOPE TAGGING;

ALDEHYDES; ALKYLATION; AMINO ACIDS; CELL MEMBRANES; FATTY ACIDS; ISOTOPES; LIPIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR BIOLOGY; OXIDATION; PEPTIDES; POLYUNSATURATED FATTY ACIDS;

CARBONYLATION;

4 HYDROXYNONENAL; APOMYOGLOBIN; CARBONYL DERIVATIVE; FORMALDEHYDE; HYDRAZIDE; LYSINE; PEPTIDE; PLASMA PROTEIN; PROTEOME; SYNTHETIC PEPTIDE;

ARTICLE; CONTROLLED STUDY; INTRACELLULAR SIGNALING; ISOTOPE ANALYSIS; LIPID PEROXIDATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CARBONYLATION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN METHYLATION;

ALDEHYDES; AMINO ACID SEQUENCE; ANIMALS; APOPROTEINS; BLOOD PROTEINS; CHROMATOGRAPHY, LIQUID; HORSES; HUMANS; ISOTOPE LABELING; LIPID PEROXIDATION; MOLECULAR SEQUENCE DATA; MYOGLOBIN; PEPTIDES; PROTEIN CARBONYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; TANDEM MASS SPECTROMETRY;

EID: 80054814240     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1978     Document Type: Article

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