Respiratory illnesses in Canadian health care workers: A pilot study of influenza vaccine and oseltamivir prophylaxis during the 2007/2008 influenza season

Influenza and other Respiratory Viruses

Volumn 5, Issue 6, 2011, Pages 404-408

  Coleman, Brenda L ^a,b,c   Boggild, Andrea K ^a,b,d   Drews, Steven J ^c,e   Li, Yan ^f   Low, Donald E ^a,b,g   Mcgeer, Allison J ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

^d TORONTO GENERAL HOSPITAL   (Canada)

^e ProvLab   (Canada)

^f PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^g PUBLIC HEALTH ONTARIO   (Canada)

Author keywords

Acute respiratory illness; Health care worker; Influenza; Influenza vaccine; Neuraminidase inhibitors; Oseltamivir

Indexed keywords

FLUVIRAL; INFLUENZA VACCINE; OSELTAMIVIR; UNCLASSIFIED DRUG;

ACUTE RESPIRATORY TRACT DISEASE; ADULT; AGED; ANTIVIRAL THERAPY; ARTICLE; CANADA; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DISEASE DURATION; DRUG EFFICACY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; HEALTH CARE PERSONNEL; HUMAN; INFLUENZA VACCINATION; MALE; NOSE SMEAR; PATIENT COMPLIANCE; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEASONAL INFLUENZA; THROAT CULTURE; TREATMENT DURATION; UNSPECIFIED SIDE EFFECT;

ADULT; ANTIVIRAL AGENTS; CANADA; FEMALE; HEALTH PERSONNEL; HUMANS; INFLUENZA VACCINES; INFLUENZA, HUMAN; MALE; MIDDLE AGED; OSELTAMIVIR; PILOT PROJECTS; SEASONS; YOUNG ADULT;

EID: 80054791719     PISSN: 17502640     EISSN: 17502659     Source Type: Journal    
DOI: 10.1111/j.1750-2659.2011.00245.x     Document Type: Article

References (25)

1. Sullivan KM, Monto AS, Longini IM Jr. Estimates of the US health impact of influenza. Am J Public Health 1993; 83:1712-1716.
2. Edwards KM, Dupont WD, Westrich MK, Plummer WD Jr, Palmer PS, Wright PF. A randomized controlled trial of cold-adapted and inactivated vaccines for the prevention of influenza A disease. J Infect Dis 1994; 169:68-76.
3. Ohmit SE, Victor JC, Teich ER et al. Prevention of symptomatic seasonal influenza in 2005-2006 by inactivated and live attenuated vaccines. J Infect Dis 2008; 198:312-317.
4. National Advisory Committee on Immunization (NACI). Statement on influenza vaccination for the 2008-2009 season. An Advisory Committee Statement (ACS). Can Commun Dis Rep 2008; 34(ACS-3):1-46.
5. Fiore AE, Shay DK, Broder K et al. Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009. MMWR Morbid Mortal Wkly Rep 2009; 58(RR-8):1-52.
6. Kwong JC, Rosella LC, Johansen H. Trends in influenza vaccination in Canada, 1996/1997 to 2005. Health Rep 2007; 18:9-19.
7. Lu P, Bridges CB, Euler GL, Singleton JA. Influenza vaccination of recommended adult populations, U.S., 1989-2005. Vaccine 2008; 26:1786-1793.
8. Jefferson T, Di Pietrantonj C, Al-Ansary LA, Ferroni E, Thorning S, Thomas RE. Vaccines for preventing influenza in the elderly. Cochrane Database Syst Rev 2010; 2:CD004876.
9. Avetisyan G, Aschan J, Hassan M, Ljungman P. Evaluation of immune responses to seasonal influenza vaccination in healthy volunteers and in patients after stem cell transplantation. Transplantation 2008; 86:257-263.
10. Chalumeau HP. Vaccine manufacture at the time of a pandemic influenza. Eur J Epidemiol 1994; 10:487-490.
11. Jefferson T, Jones M, Doshi P, Del Mar C. Neuraminidase inhibitors for preventing and treating influenza in healthy adults: systematic review and meta-analysis. BMJ 2009; 339:b5106. doi:
12. Shun-Shin M, Thompson M, Heneghan C, Perera R, Harnden A, Mant D. Neuraminidase inhibitors for treatment and prophylaxis of influenza in children: systematic review and meta-analysis of randomised controlled trials. BMJ 2009; 339:b3172. doi:
13. Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team, Dawood FS, Jain S, Finelli L et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009; 360:2605-2615.
14. Drews SJ, Blair J, Lombos E et al. Use of the Seeplex RV Detection kit for surveillance of respiratory viral outbreaks in Toronto, Ontario, Canada. Ann Clin Lab Sci 2008; 38:376-379.
15. Kuster SP, Drews S, Green K et al. Epidemiology of influenza-associated hospitalization in adults, Toronto, 2007/8. Eur J Clin Microbiol Infect Dis 2010; 29:835-843.
16. Michiels B, Philips H, Coenen S et al. The effect of giving influenza vaccination to general practitioners: a controlled trial [NCT00221676]. BMC Med 2006; 4:17.
17. Evans CT, LaVela SL, Smith B, Wallace C, Goldstein B, Weaver FM. Response to the 2004-2005 influenza vaccine shortage in veterans with spinal cord injuries and disorders and their providers. J Spinal Cord Med 2007; 30:20-26.
18. Weingarten S, Riedinger M, Bolton LB, Miles P, Ault M. Barriers to influenza vaccine acceptance. A survey of physicians and nurses. Am J Infect Control 1989; 17:202-207.
19. Reyes F, Aziz S, Winchester B et al. Influenza in Canada: 2007-2008 season update. Can Commun Dis Rep 2008; 34:1-9.
20. Hayden FG, Atmar RL, Schilling M et al. Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza. N Engl J Med 1999; 341:1336-1343.
21. Belmaker I, Lyandres M, Bilenko N et al. Adherence with oseltamivir chemoprophylaxis among workers exposed to poultry during avian influenza outbreaks in southern Israel. Int J Infect Dis 2009; 13:261-265.
22. Crout LA, Chang E, Cioffi J. Why do registered nurses work when ill? J Nurs Adm 2005; 35:23-28.
23. Aronsson G, Gustafsson K, Dallner M. Sick but yet at work. An empirical study of sickness presenteeism. J Epidemiol Community Health 2000; 54:502-509.
24. Khazeni N, Hutton DW, Garber AM, Owens DK. Effectiveness and cost-effectiveness of expanded antiviral prophylaxis and adjuvanted vaccination strategies for an influenza A (H5N1) pandemic. Ann Intern Med 2009; 151:840-853.
25. Maltezou HC, Tsiodras S. Antiviral agents for influenza: molecular targets, concerns of resistance, and new treatment options. Curr Drug Targets 2009; 10:1041-1048.