Retroviral integration mutagenesis in mice and comparative analysis in human AML identify reduced PTP4A3 expression as a prognostic indicator

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Beekman, Renée ^a   Valkhof, Marijke ^a   Erkeland, Stefan J ^a   Taskesen, Erdogan ^a   Rockova, Veronika ^a   Peeters, Justine K ^a   Valk, Peter J M ^a   Löwenberg, Bob ^a   Touw, Ivo P ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE TYPE IVA; UNCLASSIFIED DRUG; PTP4A3 PROTEIN, HUMAN; TUMOR PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA METHYLATION; GENE IDENTIFICATION; GENE LOCATION; GENE MAPPING; HEMATOPOIETIC CELL SPECIFIC LYN SUBSTRATE 1 GENE; HUMAN; HUMAN CELL; LEUKEMOGENESIS; LYMPHOID RESTRICTED MEMBRANE PROTEIN GENE; MOUSE; MUTAGENESIS; NONHUMAN; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN KINASE INTERFERON INDUCIBLE DOUBLE STRANDED RNA DEPENDENT INHIBITOR REPRESSOR OF P58 GENE; PROTEIN TYROSINE PHOSPHATASE TYPE IVA GENE; RETROVIRAL INTEGRATION MUTAGENESIS; TUMOR GENE; ANIMAL; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HAPLOINSUFFICIENCY; MIDDLE AGED; MURINE LEUKEMIA VIRUS; PHYSIOLOGY; POLYMERASE CHAIN REACTION; VIROLOGY; VIRUS DNA CELL DNA INTERACTION;

MUS;

ANIMALS; DNA METHYLATION; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HAPLOINSUFFICIENCY; HUMANS; LEUKEMIA VIRUS, MURINE; LEUKEMIA, MYELOID, ACUTE; MICE; MIDDLE AGED; MUTAGENESIS; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; PROGNOSIS; PROTEIN TYROSINE PHOSPHATASES; TRANSCRIPTION, GENETIC; VIRUS INTEGRATION;

EID: 80054782049     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026537     Document Type: Article

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