Misalignment of PLP/DM20 transmembrane domains determines protein misfolding in Pelizaeus-Merzbacher disease

Journal of Neuroscience

Volumn 31, Issue 42, 2011, Pages 14961-14971

  Dhaunchak, Ajit Singh ^a,b   Colman, David R ^b   Nave, Klaus Armin ^a  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DM20 PROTEIN; MUTANT PROTEIN; MYELIN PROTEIN; PLP1 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONTROLLED STUDY; CROSS LINKING; DISULFIDE BOND; ENDOPLASMIC RETICULUM; ENDOSOME; GENE; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; OLIGODENDROGLIA; PELIZAEUS MERZBACHER DISEASE; PLP1 GENE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN MISFOLDING; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN TRANSPORT;

ANIMALS; CELL LINE, TRANSFORMED; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; ENDOPLASMIC RETICULUM; GREEN FLUORESCENT PROTEINS; HUMANS; MODELS, MOLECULAR; MYELIN PROTEOLIPID PROTEIN; OLIGODENDROGLIA; PAPAIN; PELIZAEUS-MERZBACHER DISEASE; POINT MUTATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; TRANSFECTION;

EID: 80054770781     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2097-11.2011     Document Type: Article

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