Disease-associated mutations cause premature oligomerization of myelin proteolipid protein in the endoplasmic reticulum

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 12, 2005, Pages 4342-4347

  Swanton, Eileithyia ^a   Holland, Andrew ^a   High, Stephen ^a   Woodman, Philip ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Endoplasmic reticulum; Membrane protein; Oligomer; Pelizaeus Merzbacher disease; Quality control

Indexed keywords

MUTANT PROTEIN; PROTEOLIPID PROTEIN;

ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; DEMYELINATING DISEASE; DISEASE SEVERITY; ENDOPLASMIC RETICULUM; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; NONHUMAN; OLIGODENDROGLIA; OLIGOMERIZATION; PELIZAEUS MERZBACHER DISEASE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROCESSING;

AMINO ACID SUBSTITUTION; ANIMALS; COS CELLS; DISULFIDES; ENDOPLASMIC RETICULUM; HELA CELLS; HUMANS; MODELS, MOLECULAR; MUTATION; MUTATION, MISSENSE; MYELIN PROTEOLIPID PROTEIN; OLIGODENDROGLIA; PELIZAEUS-MERZBACHER DISEASE; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SODIUM DODECYL SULFATE; SURFACE-ACTIVE AGENTS; TRANSFECTION;

EID: 15444381131     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0407287102     Document Type: Article

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