Anti-ribosomal P antibodies and lupus nephritis.

Clinical and Experimental Nephrology

Volumn 15, Issue 4, 2011, Pages 471-477

  Hirohata, Shunsei ^a  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Anti DNA antibodies; Anti ribosomal P antibodies; Lupus nephritis; Pathogenesis; Systemic lupus erythematosus

Indexed keywords

AUTOANTIBODY; DOUBLE STRANDED DNA ANTIBODY; ENDOTHELIAL CELL ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; LIPOPROTEIN LIPASE; PHOSPHOPROTEIN; RIBOSOMAL P ANTIBODY; UNCLASSIFIED DRUG;

CROSS REACTION; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE COURSE; HISTOPATHOLOGY; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; LUPUS ERYTHEMATOSUS NEPHRITIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PROGNOSIS; REVIEW; SYSTEMIC LUPUS ERYTHEMATOSUS; TH1 CELL;

AMINO ACID SEQUENCE; ANIMALS; AUTOANTIBODIES; CROSS REACTIONS; DNA; HUMANS; LUPUS NEPHRITIS; MICE; PHOSPHOPROTEINS; RIBOSOMAL PROTEINS; TH1 CELLS;

EID: 80054766398     PISSN: 13421751     EISSN: 14377799     Source Type: Journal    
DOI: 10.1007/s10157-011-0462-9     Document Type: Review

References (46)

1. Elkon K, Skelly S, Parnassa A, Moller W, Danho W, Weissbach H, et al. Identification and chemical synthesis of a ribosomal protein antigenic determinant in systemic lupus erythematosus. Proc Natl Acad Sci USA. 1986;83:7419-23 (Pubitemid 16000533)
2. Bonfa E, Golombek SJ, Kaufman LD, Skelly S, Weissbach H, Brot N, et al. Association between lupus psychosis and antiribosomal P protein antibodies. N Engl J Med. 1987;317:265-71 (Pubitemid 17100105)
3. Schneebaum AB, Singleton JD, West SG, Blodgett JK, Allen LG, Cheronis JC, et al. Association of psychiatric manifestations with antibodies to ribosomal P proteins in systemic lupus erythematosus. Am J Med. 1991;90:54-62
4. Elkon KB, Bonfa E, Llovet R, Eisenberg RA. Association between anti-Sm and anti-ribosomal P protein autoantibodies in human systemic lupus erythematosus and MRL/lpr mice. J Immunol. 1989;143:1549-54 (Pubitemid 19217417)
5. Satoh M, Hamilton KJ, Ajmani AK, Dong X, Wang J, Kanwar YS, et al. Autoantibodies to ribosomal P antigens with immune complex glomerulonephritis in SJL mice treated with pristane. J Immunol. 1996;157:3200-6 (Pubitemid 126450084)
6. Koffler D, Schur PH, Kunkel HG. Immunological studies concerning the nephritis of systemic lupus erythematosus. J Exp Med. 1967;126:607-24
7. Lambert PH, Dixon FJ. Pathogenesis of the glomerulonephritis of NZB/W mice. J Exp Med. 1968;127:507-22
8. Livinsky RJ, Cameron JS, Soothill JF. Serum immune complexes and disease activity in lupus nephritis. Lancet. 1977;i:564-7 (Pubitemid 8048851)
9. Jacob L, Lety MA, Louvard D, Bach JF. Binding of monoclonal anti-DNA autoantibodies to identical protein(s) present at the surface of several human cell types involved in lupus pathogenesis. J Clin Invest. 1985;75:315-7 (Pubitemid 15164001)
10. Jacob L, Tron F, Bach JF, Louvard D. A monoclonal anti-DNA antibody also binds to cell-surface protein(s). Proc Natl Acad Sci USA. 1984;81:3843-5 (Pubitemid 14087814)
11. Raz E, Ben-Bassat H, Davidi T, Shlomai Z, Eilat D. Crossreactions of anti-DNA autoantibodies with cell surface proteins. Eur J Immunol. 1993;23:383-90 (Pubitemid 23075067)
12. Sun KH, Liu WT, Tsai CY, Tang SJ, Han SH, Yu CL. AntidsDNA antibodies cross-react with ribosomal P proteins expressed on the surface of glomerular mesangial cells to exert a cytostatic effect. Immunology. 1995;85:262-9
13. Sun KH, Liu WT, Tang SJ, Tsai CY, Hsieh SC, Wu TH, et al. The expression of acidic ribosomal phosphoproteins on the surface membrane of different tissues in autoimmune and normal mice which are the target molecules for anti-double-stranded DNA antibodies. Immunology. 1996;87:362-71
14. Martin AL, Reichlin M. Fluctuations of antibody to ribosomal P proteins correlate with appearance and remission of nephritis in SLE. Lupus. 1996;5:22-9 (Pubitemid 26072425)
15. Chindalore V, Neas B, Reichlin M. The association between antiribosomal P antibodies and active nephritis in systemic lupus erythematosus. Clin Immunol Immunopathol. 1998;87:292-6 (Pubitemid 28285445)
16. Reichlin M, Broyles TF, Hubscher O, James J, Lehman TA, Palermo R, et al. Prevalence of autoantibodies to ribosomal P proteins in juvenile-onset systemic lupus erythematosus compared with the adult disease. Arthritis Rheum. 1999;42:69-75 (Pubitemid 29042572)
17. Takeda I, Rayno K, Movafagh FB, Wolfson-Reichlin M, Reichlin M. Dual binding capabilities of anti-double-stranded DNA antibodies and anti-ribosomal phosphoprotein (P) antibodies. Lupus. 2001;10:857-65 (Pubitemid 34016863)
18. Koren E, Reichlin MW, Koscec M, Fugate RD, Reichlin M. Autoantibodies to the ribosomal P proteins react with a plasma membrane-related target on human cells. J Clin Invest. 1992;89:1236-41
19. Hirohata S, Nakanishi K. Antiribosomal P protein antibody in human systemic lupus erythematosus reacts specifically with activated T cells. Lupus. 2001;10:612-21 (Pubitemid 32959275)
20. Nagai T, Arinuma Y, Yanagida T, Yamamoto K, Hirohata S. Anti-ribosomal P protein antibody in human systemic lupus erythematosus up-regulates the expression of proinflammatory cytokines by human peripheral blood monocytes. Arthritis Rheum. 2005;52:847-55 (Pubitemid 40365108)
21. Romagnani S. The Th1/Th2 paradigm. Immunol Today. 1997;18:263-6 (Pubitemid 27261442)
22. Mosmann TR, Coffman RL. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol. 1989;7:145-73 (Pubitemid 19138011)
23. Kamogawa Y, Minasi LA, Carding SR, Bottomly K, Flavell RA. The relationship of IL-4- and IFN gamma-producing T cells studied by lineage ablation of IL-4-producing cells. Cell. 1993;75:985-95
24. Wolf SF, Temple PA, Kobayashi M, Young D, Dicig M, Lowe L, et al. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J Immunol. 1991;146:3074-81
25. Trinchieri G. Interleukin-12 and its role in the generation of Th1 cells. Immunol Today. 1993;14:335-8 (Pubitemid 23198164)
26. Manetti R, Parronchi P, Giudizi MG, Piccinni MP, Maggi E, Trinchieri G, et al. Natural killer cell stimulatory factor (interleukin 12 [IL12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med. 1993;177:1199-204 (Pubitemid 23097410)
27. Schmitt E, Hoehn P, Germann T, Rüde E. Differential effects of interleukin-12 on the development of naive mouse CD4? T cells. Eur J Immunol. 1994;24:343-7 (Pubitemid 24041122)
28. Nagai T, Yanagida T, Hirohata S. Anti-ribosomal P protein antibody induces Th1 responses by enhancing the production of IL-12 in activated monocytes. Mod Rheumatol. 2011;21:57-62
29. Akahoshi M, Nakashima H, Tanaka Y, Kohsaka T, Nagano S, Ohgami E, et al. Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus. Arthritis Rheum. 1999;42:1644-8 (Pubitemid 30263632)
30. Tucci M, Lombardi L, Richards HB, Dammacco F, Silvestris F. Overexpression of interleukin-12 and T helper 1 predominance in lupus nephritis. Clin Exp Immunol. 2008;154:247-54
31. Tipping PG, Kitching AR. Glomerulonephritis, Th1 and Th2: What's new? Clin Exp Immunol. 2005;142:207-15 (Pubitemid 41565235)
32. do Nascimento AP, Viana Vdos S, Testagrossa Lde A, Leon EP, Borba EF, Barros RT, et al. Antibodies to ribosomal P proteins: A potential serologic marker for lupus membranous glomerulonephritis. Arthritis Rheum. 2006;54:1568-72
33. Frampton G, Moriya S, Pearson JD, Isenberg DA, Ward FJ, Smith TA, et al. Identification of candidate endothelial cell autoantigens in systemic lupus erythematosus using a molecular cloning strategy: A role for ribosomal P protein P0 as an endothelial cell autoantigen. Rheumatology. 2000;39:1114-20
34. Yoshio T, Masuyama J, Kano S. Antiribosomal P0 protein antibodies react with the surface of human umbilical vein endothelial cells. J Rheumatol. 1996;23:1311-2 (Pubitemid 126785761)
35. Reichlin M, Wolfson-Reichlin M. Correlations of anti-dsDNA and anti-ribosomal P autoantibodies with lupus nephritis. Clin Immunol. 2003;108:69-72 (Pubitemid 36809218)
36. Massardo L, Burgos P, Martínez ME, Pérez R, Calvo M, Barros J, et al. Antiribosomal P protein antibodies in Chilean SLE patients: No association with renal disease. Lupus. 2002;11:379-83 (Pubitemid 34760636)
37. Chandran V, Upadhyaya SK, Haroon N, Aggarwal A, Misra R. Lack of clinical association with antibodies to ribosomal P proteins in Indian patients with systemic lupus erythematosus. J Rheumatol. 2006;33:1987-9 (Pubitemid 44571871)
38. Quintana G, Coral-Alvarado P, Aroca G, Patarroyo PM, Chalem P, Iglesias-Gamarra A, et al. Single anti-P ribosomal antibodies are not associated with lupus nephritis in patients suffering from active systemic lupus erythematosus. Autoimmun Rev. 2010;9:750-5
39. Reichlin M, Wolfson-Reichlin M. Evidence for the participation of anti-ribosomal P antibodies in lupus nephritis. Arthritis Rheum. 1999;42:2728-9 (Pubitemid 30327199)
40. Xie C, Liang Z, Chang S, Mohan C. Use of a novel elution regimen reveals the dominance of polyreactive antinuclear autoantibodies in lupus kidneys. Arthritis Rheum. 2003;48:2343-52 (Pubitemid 36959217)
41. Haddouk S, Marzouk S, Jallouli M, Fourati H, Frigui M, Hmida YB, et al. Clinical and diagnostic value of ribosomal P autoantibodies in systemic lupus erythematosus. Rheumatology. 2009;48:953-7
42. Sugisaki K, Takeda I, Kanno T, Nogai S, Abe K, Sakuma H, et al. An anti-nuclear antibody-negative patient with systemic lupus erythematosus (SLE) accompanied with anti-ribosomal P antibody (anti-P). Intern Med. 2002;41:1047-51 (Pubitemid 35423099)
43. Reichlin M. Serological correlations with nephritis in systemic lupus erythematosus. Clin Immunol. 2005;117:12-4 (Pubitemid 41725464)
44. Bertolaccini ML, Murru V, Khamashta MA. Lack of association of antibodies to ribosomal P proteins with lupus membranous glomerulonephritis: Comment on the article by Do Nascimento et al. Arthritis Rheum. 2006;54:4025-6 (Pubitemid 44955908)
45. do Nascimento AP, Viana Vdos S, Testagrossa Lde A, Leon EP, Borba EF, Barros RT, et al. Author's reply. Arthritis Rheum. 2006;54:4026-72
46. de Macedo PA, Borba EF, Viana VD, Leon EP, Testagrossa LD, Barros RT, et al. Antibodies to ribosomal P proteins in lupus nephritis: A surrogate marker for a better renal survival? Autoimmun Rev. 2011;10(3):126-30.