Infusion of P-Capt prion-filtered red blood cell products demonstrate acceptable in vivo viability and no evidence of neoantigen formation

Transfusion

Volumn 51, Issue 10, 2011, Pages 2228-2236

  Cancelas, Jose A ^a,b,c   Rugg, Neeta ^a,b,c   Pratt, P Gayle ^a,b,c   Worsham, D Nicole ^a,b,c   Pehta, Joan C ^a,b,c   Banks, Kate ^a,b,c   Davenport, Robertson D ^a,b,c   Judd, W John ^a,b,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b Alpha Bio Group   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANTIGEN EXPRESSION; ARTICLE; BLOOD FILTER; BLOOD FILTRATION; CELL VIABILITY; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROCYTE TRANSFUSION; HUMAN; IN VITRO STUDY; LEUKOCYTE COUNT; PRION; SAFETY;

ADULT; BLOOD CHEMICAL ANALYSIS; BLOOD PRESERVATION; BLOOD SAFETY; BLOOD TRANSFUSION, AUTOLOGOUS; CREUTZFELDT-JAKOB SYNDROME; ERYTHROCYTE TRANSFUSION; ERYTHROCYTES; FILTRATION; HUMANS; LEUKOCYTE REDUCTION PROCEDURES; MIDDLE AGED; PRIONS; TIME FACTORS;

EID: 80054754227     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2011.03133.x     Document Type: Article

References (25)

1. Prusiner SB,. Prions. Proc Natl Acad Sci U S A 1998; 95: 13363-83. (Pubitemid 28525623)
2. Will RG, Ironside JW, Hornlimann B, Zeidler M,. Creutzfeldt-Jakob disease. Lancet 1996; 347: 65-6.
3. Gibbs CJ Jr, Gajdusek DC, Asher DM, Alpers MP, Beck E, Daniel PM, Matthews WB,. Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee. Science 1968; 161: 388-9.
4. de Marco MF, Linehan J, Gill ON, Clewley JP, Brandner S,. Large-scale immunohistochemical examination for lymphoreticular prion protein in tonsil specimens collected in Britain. J Pathol 2010; 222: 380-7.
5. Hilton DA, Ghani AC, Conyers L, Edwards P, McCardle L, Ritchie D, Penney M, Hegazy D, Ironside JW,. Prevalence of lymphoreticular prion protein accumulation in UK tissue samples. J Pathol 2004; 203: 733-9. (Pubitemid 38961558)
6. Llewelyn CA, Hewitt PE, Knight RS, Amar K, Cousens S, Mackenzie J, Will RG,. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 2004; 363: 417-21. (Pubitemid 38210057)
7. Hewitt PE, Llewelyn CA, Mackenzie J, Will RG,. Creutzfeldt-Jakob disease and blood transfusion: results of the UK transfusion medicine epidemiological review study. Vox Sang 2006; 91: 221-30. (Pubitemid 44337279)
8. Peden A, McCardle L, Head MW, Love S, Ward HJ, Cousens SN, Keeling DM, Millar CM, Hill FG, Ironside JW,. Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia. Haemophilia 2010; 16: 296-304.
9. Wilson K, Ricketts MN,. Transfusion transmission of vCJD: a crisis avoided? Lancet 2004; 364: 477-9. (Pubitemid 39070391)
10. Herzog C, Sales N, Etchegaray N, Charbonnier A, Freire S, Dormont D, Deslys JP, Lasmézas CI,. Tissue distribution of bovine spongiform encephalopathy agent in primates after intravenous or oral infection. Lancet 2004; 363: 422-8. (Pubitemid 38210058)
11. Gregori L, Gurgel PV, Lathrop JT, Edwardson P, Lambert BC, Carbonell RG, Burton SJ, Hammond DJ, Rohwer RG,. Reduction in infectivity of endogenous transmissible spongiform encephalopathies present in blood by adsorption to selective affinity resins. Lancet 2006; 368: 2226-30. (Pubitemid 44959015)
12. Gregori L, McCombie N, Palmer D, Birch P, Sowemimo-Coker SO, Giulivi A, Rohwer RG,. Effectiveness of leucoreduction for removal of infectivity of transmissible spongiform encephalopathies from blood. Lancet 2004; 364: 529-31. (Pubitemid 39070414)
13. Gregori L, Gray BN, Rose E, Spinner DS, Kascsak RJ, Rohwer RG,. A sensitive and quantitative assay for normal PrP in plasma. J Virol Methods 2008; 149: 251-9.
14. Atarashi R, Satoh K, Sano K, Fuse T, Yamaguchi N, Ishibashi D, Matsubara T, Nakagaki T, Yamanaka H, Shirabe S, Yamada M, Mizusawa H, Kitamoto T, Klug G, McGlade A, Collins SJ, Nishida N,. Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion. Nat Med 2011; 17: 175-8.
15. Gregori L, Lambert BC, Gurgel PV, Gheorghiu L, Edwardson P, Lathrop JT, Macauley C, Carbonell RG, Burton SJ, Hammond D, Rohwer RG,. Reduction of transmissible spongiform encephalopathy infectivity from human red blood cells with prion protein affinity ligands. Transfusion 2006; 46: 1152-61. (Pubitemid 44139489)
16. Cahill MR, Murphy T, Khan M, Fagan J, Murphy WG,. Phase I/II safety study of transfusion of prion-filtered red cell concentrates in transfusion-dependent patients. Vox Sang 2010; 99: 174-6.
17. Murphy CV, Eakins E, Fagan J, Croxon H, Murphy WG,. In vitro assessment of red-cell concentrates in SAG-M filtered through the MacoPharma P-CAPT prion-reduction filter. Transfus Med 2009; 19: 109-16.
18. Wiltshire M, Thomas S, Scott J, Hicks V, Haines M, Cookson P, Garwood M, Cardigan R,. Prion reduction of red blood cells: impact on component quality. Transfusion 2010; 50: 970-9.
19. UK-Blood-Services. Evaluation of new red cell components for transfusion. Guidelines for the Blood Transfusion Services in the UK TSO (The Stationery Office). 7th ed. London: The Stationery Office; 2005. p. 119-21.
20. Council of Europe. Red cells, in additive solution. Guide to the preparation, use and quality assurance of blood components. 2007;Chapter 12-14: 113-28.
21. Lathtrop M, Poncheri M, Gheorghiu L, Hammond D,. Storage study of red blood cells treated witht the MacoPharma P-Capt prion removal filter. Transfus Med 2006; 16: 36.
22. Barclay GR, Walker B, Gibson J, McColl K, Turner ML,. Quality assurance by a commercial flow cytometry method of leucodepletion of whole blood donations: initial application of universal testing and proposals for a batch-release sampling plan. Transfus Med 2000; 10: 37-48. (Pubitemid 30166236)
23. International Committee for Standardization in Haematology. Recommended method for radioisotope red-cell survival studies. Br J Haematol 1980; 45: 659-66.
24. Moroff GS, Sohmer PR, Button LN,. Proposed standardization of methods for determining the 24-hour survival of stored red cells. Transfusion 1984; 24: 109-14. (Pubitemid 14135415)
25. Marsh WL, Jenkins WJ,. Anti-i: a new cold antibody. Nature 1960; 188: 753.