Protection against adriamycin-induced cardiomyopathy by carnosine in rats: Role of endogenous antioxidants

Biological Trace Element Research

Volumn 143, Issue 1, 2011, Pages 412-424

  Dursun, Nurcan ^a   Taşkın, Eylem ^a   Öztürk, Figen ^a  

^a ERCIYES UNIVERSITY   (Turkey)

Author keywords

Adriamycin; Antioxidant enzymes; Carnosine; ECG; Isolated rat heart

Indexed keywords

CARNOSINE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; CREATINE KINASE; DOXORUBICIN; GLUTATHIONE PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CARDIOMYOPATHY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; ELECTROCARDIOGRAM; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INACTIVATION; HEART HEMODYNAMICS; HEART PROTECTION; HISTOPATHOLOGY; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; TREATMENT DURATION;

RATTUS;

EID: 80054753546     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-010-8875-y     Document Type: Article

References (48)

1. RC Young RF Ozols CE Myers 1981 The anthracycline antineoplastic drugs N Engl J Med 305 139 153 7017406 10.1056/NEJM198107163050305 1:CAS:528: DyaL3MXkslartLs%3D
2. L Chularojmontri SK Wattanapitayakul A Herunsalee, et al. 2005 Antioxidative and cardioprotective effects of Phyllanthus urinaria L. on doxorubicin-induced cardiotoxicity Biol Pharm Bull 28 1165 1171 15997091 10.1248/bpb.28.1165 1:CAS:528:DC%2BD2MXpsFaiu70%3D
3. GY Zhou BL Zhao JW Hou GE Ma WJ Xin 1999 Protective effects of sodium tanshinone IIA sulphonate against adriamycin-induced lipid peroxidation in mice hearts in vivo and in vitro Pharmacol Res 40 487 491 10660946 10.1006/phrs.1999.0545 1:CAS:528:DC%2BD3cXltFaisA%3D%3D
4. N Iliskovic PK Singal 1997 Lipid lowering: an important factor in preventing adriamycin-induced heart failure Am J Pathol 150 727 734 9033285 1:CAS:528:DyaK2sXhtlSrt7k%3D
5. LA Bharadwaj GF Davies IJ Xavier N Ovsenek 2002 l-carnosine and verapamil inhibit hypoxia-induced expression of hypoxia inducible factor (HIF-1 alpha) in H9c2 cardiomyoblasts Pharmacol Res 45 175 181 11884212 10.1006/phrs.2001.0911 1:CAS:528:DC%2BD38Xhs1ylu7w%3D
6. JH Kang 2007 Protective effects of carnosine and N-acetylcarnosine on salsolinol-mediated Cu, Zn-superoxide dismutase inactivation Bull Korean Chem Soc 28 1881 1884 10.5012/bkcs.2007.28.10.1881 1:CAS:528:DC%2BD2sXhsValtbzI
7. JH Kang KS Kim SY Choi, et al. 2002 Protective effects of carnosine, homocarnosine and anserine against peroxyl radical-mediated Cu, Zn-superoxide dismutase modification Biochim Biophys Acta 1570 89 96 11985892 1:CAS:528:DC%2BD38Xjtl2ksbk%3D
8. D Fitzpatrick JF Amend RL Squibb H Fisher 1980 Effects of chronic and acute infections on tissue levels of carnosine, anserine and free histidine in rats and chickens Proc Soc Exp Biol Med 165 404 408 7465552 1:CAS:528: DyaL3MXotFGrtg%3D%3D
9. DE Fisher JF Amend DH Strumeyer H Fisher 1978 A role for carnosine and anserine in histamine metabolism of the traumatized rat Proc Soc Exp Biol Med 158 402 405 684011 1:CAS:528:DyaE1cXlt1Oitb8%3D
10. JE Parrillo MM Parker C Natanson, et al. 1990 Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy Ann Intern Med 113 227 242 2197912 1:STN:280:DyaK3czivVGntg%3D%3D
11. GP Zaloga PR Roberts KW Black, et al. 1997 Carnosine is a novel peptide modulator of intracellular calcium and contractility in cardiac cells Am J Physiol 272 H462 H468 9038968 1:CAS:528:DyaK2sXht1Wls70%3D
12. JW Lee H Miyawaki EV Bobst, et al. 1999 Improved functional recovery of ischemic rat hearts due to singlet oxygen scavengers histidine and carnosine J Mol Cell Cardiol 31 113 121 10072720 10.1006/jmcc.1998.0850 1:CAS:528: DyaK1MXhvVWmtrw%3D
13. K Uchida S Kawakishi 1994 Identification of oxidized histidine generated at the active site of Cu, Zn-superoxide dismutase exposed to H2O2. Selective generation of 2-oxo-histidine at the histidine 118 J Biol Chem 269 2405 2410 8300566 1:CAS:528:DyaK2cXhsFOntb0%3D
14. SY Choi HY Kwon OB Kwon JH Kang 1999 Hydrogen peroxide-mediated Cu, Zn-superoxide dismutase fragmentation: protection by carnosine, homocarnosine and anserine Biochim Biophys Acta 1472 651 657 10564779 1:CAS:528: DyaK1MXntlClt7o%3D
15. SL Jewett AM Rocklin M Ghanevati JM Abel JA Marach 1999 A new look at a time-worn system: oxidation of CuZn-SOD by H2O2 Free Radic Biol Med 26 905 918 10232834 10.1016/S0891-5849(98)00274-3 1:CAS:528:DyaK1MXislGksLY%3D
16. G Begum A Cunliffe M Leveritt 2005 Physiological role of carnosine in contracting muscle Int J Sport Nutr Exerc Metab 15 493 514 16327029 1:CAS:528:DC%2BD2MXhtFyiu7zO
17. AR Hipkiss JE Preston DT Himsworth, et al. 1998 Pluripotent protective effects of carnosine, a naturally occurring dipeptide Ann NY Acad Sci 854 37 53 9928418 10.1111/j.1749-6632.1998.tb09890.x 1:CAS:528:DyaK1MXjtVejtA%3D%3D
18. NV Dimitrov MB Hay S Siew, et al. 1987 Abrogation of adriamycin-induced cardiotoxicity by selenium in rabbits Am J Pathol 126 376 383 3826299 1:CAS:528:DyaL2sXhs1ymtLc%3D
19. B Baykara I Tekmen C Pekcetin, et al. 2009 The protective effects of carnosine and melatonin in ischemia-reperfusion injury in the rat liver Acta Histochem 111 42 51 18554692 10.1016/j.acthis.2008.03.002 1:CAS:528: DC%2BD1MXjt1ShtL0%3D
20. YT Lee CC Hsu MH Lin KS Liu MC Yin 2005 Histidine and carnosine delay diabetic deterioration in mice and protect human low density lipoprotein against oxidation and glycation Eur J Pharmacol 513 145 150 15878720 10.1016/j.ejphar.2005.02.010 1:CAS:528:DC%2BD2MXjvVOhsbw%3D
21. K Mikami M Otaka D Watanabe, et al. 2006 Zinc L-carnosine protects against mucosal injury in portal hypertensive gastropathy through induction of heat shock protein 72 J Gastroenterol Hepatol 21 1669 1674 16984587 10.1111/j.1440-1746.2006.04328.x 1:CAS:528:DC%2BD28Xht1erurfO
22. SY Saad TA Najjar MM Arafah 2006 Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats Basic Clin Pharmacol Toxicol 99 412 417 17169121 10.1111/j.1742-7843.2006.pto-523.x 1:CAS:528:DC%2BD2sXhs1WisA%3D%3D
23. SK Jain 1988 Evidence for membrane lipid peroxidation during the in vivo aging of human erythrocytes Biochim Biophys Acta 937 205 210 3337801 10.1016/0005-2736(88)90242-8 1:STN:280:DyaL1c7gslOkuw%3D%3D
24. J Stocks TL Dormandy 1971 The autoxidation of human red cell lipids induced by hydrogen peroxide Br J Haematol 20 95 111 5540044 10.1111/j.1365-2141.1971.tb00790.x 1:CAS:528:DyaE3MXosFSltg%3D%3D
25. DE Paglia WN Valentine 1967 Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase J Lab Clin Med 70 158 169 6066618 1:CAS:528:DyaF2sXks1Wjur8%3D
26. Y Sun LW Oberley Y Li 1988 A simple method for clinical assay of superoxide dismutase Clin Chem 34 497 500 3349599 1:CAS:528:DyaL1cXhvVamt7Y%3D
27. RF Beers Jr IW Sizer 1952 A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase J Biol Chem 195 133 140 14938361 1:CAS:528:DyaG38Xjt12juw%3D%3D
28. L Li G Takemura Y Li, et al. 2006 Preventive effect of erythropoietin on cardiac dysfunction in doxorubicin-induced cardiomyopathy Circulation 113 535 543 16449733 10.1161/CIRCULATIONAHA.105.568402 1:CAS:528:DC%2BD28XmvVSgsA%3D%3D
29. PR Roberts GP Zaloga 2000 Cardiovascular effects of carnosine Biochemistry (Mosc) 65 856 861 1:CAS:528:DC%2BD3cXlvFOltr0%3D
30. N Venkatesan 1998 Curcumin attenuation of acute adriamycin myocardial toxicity in rats Br J Pharmacol 124 425 427 9647462 10.1038/sj.bjp.0701877 1:CAS:528:DyaK1cXjslSju7s%3D
31. PW Fisher F Salloum A Das H Hyder RC Kukreja 2005 Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity Circulation 111 1601 1610 15811867 10.1161/01.CIR.0000160359.49478.C2 1:CAS:528:DC%2BD2MXislahtbY%3D
32. H le Marec W Spinelli MR Rosen 1986 The effects of doxorubicin on ventricular tachycardia Circulation 74 881 889 3757196 10.1161/01.CIR.74.4.881
33. RI Jabr WC Cole 1993 Alterations in electrical activity and membrane currents induced by intracellular oxygen-derived free radical stress in guinea pig ventricular myocytes Circ Res 72 1229 1244 8495552 1:CAS:528: DyaK3sXks1Giu7g%3D
34. P Pacher L Liaudet P Bai, et al. 2002 Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure J Pharmacol Exp Ther 300 862 867 11861791 10.1124/jpet.300.3.862 1:CAS:528:DC%2BD38XitVemtb4%3D
35. SY Saad TA Najjar AC Al-Rikabi 2001 The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats Pharmacol Res 43 211 218 11401411 10.1006/phrs.2000.0769 1:CAS:528: DC%2BD3MXisV2ksLY%3D
36. O Timioglu S Kutsal M Ozkur, et al. 1999 The effect of EGb 761 on the doxorubicin cardiomyopathy Res Commun Mol Pathol Pharmacol 106 181 192 11485048 1:STN:280:DC%2BD3MvjvFCqsg%3D%3D
37. EH Herman J Zhang N Rifai, et al. 2001 The use of serum levels of cardiac troponin T to compare the protective activity of dexrazoxane against doxorubicin- and mitoxantrone-induced cardiotoxicity Cancer Chemother Pharmacol 48 297 304 11710630 10.1007/s002800100348 1:CAS:528:DC%2BD3MXmvFGkurs%3D
38. AM Mostafa MN Nagi AC Al Rikabi OA Al-Shabanah HA El-Kashef 1999 Protective effect of aminoguanidine against cardiovascular toxicity of chronic doxorubicin treatment in rats Res Commun Mol Pathol Pharmacol 106 193 202 11485049 1:CAS:528:DC%2BD3MXlsFOhu78%3D
39. B Halliwell 1991 Reactive oxygen species in living systems: source, biochemistry, and role in human disease Am J Med 91 14S 22S 1928205 10.1016/0002-9343(91)90279-7 1:CAS:528:DyaK38Xitlartr0%3D
40. C Daosukho Y Chen T Noel, et al. 2007 Phenylbutyrate, a histone deacetylase inhibitor, protects against adriamycin-induced cardiac injury Free Radic Biol Med 42 1818 1825 17512461 10.1016/j.freeradbiomed.2007.03.007 1:CAS:528:DC%2BD2sXlsF2hsbs%3D
41. S Mukherjee SK Banerjee M Maulik, et al. 2003 Protection against acute adriamycin-induced cardiotoxicity by garlic: role of endogenous antioxidants and inhibition of TNF-alpha expression BMC Pharmacol 3 16 14687418 10.1186/1471-2210-3-16
42. T Li I Danelisen A Bello-Klein PK Singal 2000 Effects of probucol on changes of antioxidant enzymes in adriamycin-induced cardiomyopathy in rats Cardiovasc Res 46 523 530 10912462 10.1016/S0008-6363(00)00039-0 1:CAS:528:DC%2BD3cXjsVGgtr8%3D
43. PE Hartman Z Hartman KT Ault 1990 Scavenging of singlet molecular oxygen by imidazole compounds: high and sustained activities of carboxy terminal histidine dipeptides and exceptional activity of imidazole-4-acetic acid Photochem Photobiol 51 59 66 2304979 10.1111/j.1751-1097.1990.tb01684.x 1:CAS:528:DyaK3cXhslChtLs%3D
44. D Harman 1991 The aging process: major risk factor for disease and death Proc Natl Acad Sci USA 88 5360 5363 2052612 10.1073/pnas.88.12.5360 1:STN:280:DyaK3M3ntFerug%3D%3D
45. BP Sharonov N Govorova SN Lyzlova 1990 Carnosine as a potential scavenger of oxidants generated by stimulated neutrophils Biochem Int 21 61 68 2167089 1:CAS:528:DyaK3cXltFeltr8%3D
46. PE Hartman 1986 Interception of toxic agents/mutagens/carcinogens: some of nature's novel strategies Basic Life Sci 39 169 179 3767837 1:CAS:528:DyaL2sXhslShtL8%3D
47. M Fontana F Pinnen G Lucente L Pecci 2002 Prevention of peroxynitrite-dependent damage by carnosine and related sulphonamido pseudodipeptides Cell Mol Life Sci 59 546 551 11964132 10.1007/s00018-002-8446-2 1:CAS:528:DC%2BD38Xis1Wms7c%3D
48. T Nagasawa T Yonekura N Nishizawa DD Kitts 2001 In vitro and in vivo inhibition of muscle lipid and protein oxidation by carnosine Mol Cell Biochem 225 29 34 11716361 10.1023/A:1012256521840 1:CAS:528:DC%2BD3MXot12msro%3D