Computational analysis of a novel mutation in ETFDH gene highlights its long-range effects on the FAD-binding motif

BMC Structural Biology

Volumn 11, Issue , 2011, Pages

  Er, Tze Kiong ^a,b   Chen, Chih Chieh ^c   Liu, Yen Yi ^c   Chang, Hui Chiu ^b   Chien, Yin Hsiu ^d   Chang, Jan Gowth ^a,b,e   Hwang, Jenn Kang ^c   Jong, Yuh Jyh ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRON TRANSFER FLAVOPROTEIN DEHYDROGENASE; FLAVINE ADENINE NUCLEOTIDE; OXIDOREDUCTASE; UBIQUINONE DERIVATIVE; UBIQUINONE OXIDOREDUCTASE; UNCLASSIFIED DRUG; ELECTRON TRANSFERRING FLAVOPROTEIN; ELECTRON TRANSFERRING FLAVOPROTEIN DEHYDROGENASE; ELECTRON-TRANSFERRING-FLAVOPROTEIN DEHYDROGENASE; IRON SULFUR PROTEIN;

ARTICLE; BINDING SITE; CASE REPORT; CHILD; ENZYME ACTIVITY; FEMALE; GENE MUTATION; GENE SEQUENCE; HIGH RESOLUTION MELTING ANALYSIS; HUMAN; MOLECULAR DYNAMICS; MULTIPLE ACYL COA DEHYDROGENASE DEFICIENCY; PROTEIN STRUCTURE; SCHOOL CHILD; BIOLOGY; CHEMISTRY; ENZYME ACTIVATION; GENETICS; METABOLISM; MUTATION; PROTEIN TERTIARY STRUCTURE;

BINDING SITES; CHILD; COMPUTATIONAL BIOLOGY; ELECTRON-TRANSFERRING FLAVOPROTEINS; ENZYME ACTIVATION; FEMALE; FLAVIN-ADENINE DINUCLEOTIDE; HUMANS; IRON-SULFUR PROTEINS; MOLECULAR DYNAMICS SIMULATION; MULTIPLE ACYL COENZYME A DEHYDROGENASE DEFICIENCY; MUTATION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PROTEIN STRUCTURE, TERTIARY;

EID: 80054735129     PISSN: None     EISSN: 14726807     Source Type: Journal    
DOI: 10.1186/1472-6807-11-43     Document Type: Article

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