메뉴 건너뛰기




Volumn 31, Issue 42, 2011, Pages 15205-15217

Different effects of bromodeoxyuridine and [3h]thymidine incorporation into DNA on cell proliferation, position, and fate

Author keywords

[No Author keywords available]

Indexed keywords

BROMODEOXYCYTIDINE; CELL DNA; NUCLEOTIDE; THYMIDINE; TRITIUM;

EID: 80054729712     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3092-11.2011     Document Type: Article
Times cited : (108)

References (62)
  • 1
    • 0000004140 scopus 로고
    • Measurement in medicine: The analysis of method comparison studies
    • Altman D, Bland J (1983) Measurement in medicine: the analysis of method comparison studies. Statistician 32:307-317.
    • (1983) Statistician , vol.32 , pp. 307-317
    • Altman, D.1    Bland, J.2
  • 2
    • 0000162555 scopus 로고
    • Autoradiographic investigation of cell proliferation in the brains of rats and cats
    • Altman J (1963) Autoradiographic investigation of cell proliferation in the brains of rats and cats. Anat Rec 145:573-591.
    • (1963) Anat Rec , vol.145 , pp. 573-591
    • Altman, J.1
  • 3
    • 0001329309 scopus 로고
    • In: Handbook of neurochemistry (Lajtha A, ed), New York: Plenum
    • Altman J (1969) DNA metabolism and cell proliferation. In: Handbook of neurochemistry (Lajtha A, ed), pp 137-182. New York: Plenum.
    • (1969) DNA Metabolism and Cell Proliferation , pp. 137-182
    • Altman, J.1
  • 4
    • 50549215405 scopus 로고
    • Time of neuron origin in the hippocampal region. An autoradiographic study in the mouse
    • Angevine JB Jr (1965) Time of neuron origin in the hippocampal region. An autoradiographic study in the mouse. Exp Neurol Suppl 2:1-70.
    • (1965) Exp Neurol Suppl , vol.2 , pp. 1-70
    • Angevine Jr, J.B.1
  • 5
    • 0018656949 scopus 로고
    • The cellular effect of 5-bromodeoxyuridine on the mammalian embryo
    • Bannigan J, Langman J (1979) The cellular effect of 5-bromodeoxyuridine on the mammalian embryo. J Embryol Exp Morphol 50:123-135.
    • (1979) J Embryol Exp Morphol , vol.50 , pp. 123-135
    • Bannigan, J.1    Langman, J.2
  • 6
    • 0023143546 scopus 로고
    • Anomalous neural differentiation induced by 5-bromo-2′-deoxyuridine during organogenesis in the rat
    • Biggers WJ, Barnea ER, Sanyal MK (1987) Anomalous neural differentiation induced by 5-bromo-2′-deoxyuridine during organogenesis in the rat. Teratology 35:63-75.
    • (1987) Teratology , vol.35 , pp. 63-75
    • Biggers, W.J.1    Barnea, E.R.2    Sanyal, M.K.3
  • 7
    • 0018650712 scopus 로고
    • Kinetics analysis of cellular populations by means of the quantitative radioautography
    • Bourne GH, Danielli JF, eds, New York: Academic
    • Bisconte JC (1979) Kinetics analysis of cellular populations by means of the quantitative radioautography. In: International review of cytology (Bourne GH, Danielli JF, eds), pp 75-126. New York: Academic.
    • (1979) International Review of Cytology , pp. 75-126
    • Bisconte, J.C.1
  • 8
    • 84908219488 scopus 로고
    • Statistical methods for assessing agreement between two methods of clinical measurement
    • Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307-310.
    • (1986) Lancet , vol.1 , pp. 307-310
    • Bland, J.M.1    Altman, D.G.2
  • 9
    • 84990602672 scopus 로고
    • Tracer dose and availability time of thymidine and bromodeoxyuridine: Application of bromodeoxyuridine in cell kinetic studies
    • Böswald M, Harasim S, Maurer-Schultze B (1990) Tracer dose and availability time of thymidine and bromodeoxyuridine: application of bromodeoxyuridine in cell kinetic studies. Cell Tissue Kinet 23:169-181.
    • (1990) Cell Tissue Kinet , vol.23 , pp. 169-181
    • Böswald, M.1    Harasim, S.2    Maurer-Schultze, B.3
  • 10
    • 36749026210 scopus 로고    scopus 로고
    • Everything that glitters isn't gold: A critical review of postnatal neural precursor analyses
    • Breunig JJ, Arellano JI, Macklis JD, Rakic P (2007) Everything that glitters isn't gold: a critical review of postnatal neural precursor analyses. Cell Stem Cell 1:612-627.
    • (2007) Cell Stem Cell , vol.1 , pp. 612-627
    • Breunig, J.J.1    Arellano, J.I.2    Macklis, J.D.3    Rakic, P.4
  • 11
    • 0009809146 scopus 로고
    • Biochemistry of cancer metabolic aspects
    • Brockman RW, Anderson EP (1963) Biochemistry of cancer (metabolic aspects). Annu Rev Biochem 32:463-512.
    • (1963) Annu Rev Biochem , vol.32 , pp. 463-512
    • Brockman, R.W.1    Anderson, E.P.2
  • 12
    • 29144523018 scopus 로고    scopus 로고
    • 5-Bromo-2-deoxyuridine is selectively toxic to neuronal precursors in vitro
    • Caldwell MA, He X, Svendsen CN (2005) 5-Bromo-2-deoxyuridine is selectively toxic to neuronal precursors in vitro. Eur J Neurosci 22:2965-2970.
    • (2005) Eur J Neurosci , vol.22 , pp. 2965-2970
    • Caldwell, M.A.1    He, X.2    Svendsen, C.N.3
  • 13
    • 84907126878 scopus 로고
    • Section thickness and grain count variation in tritium autoradiography
    • Caviness VS Jr, Barkley DS (1971) Section thickness and grain count variation in tritium autoradiography. Stain Technol 46:131-135.
    • (1971) Stain Technol , vol.46 , pp. 131-135
    • Caviness Jr., V.S.1    Barkley, D.S.2
  • 15
    • 0027767745 scopus 로고
    • Modulation of the cell cycle contributes to the parcellation of the primate visual cortex
    • Dehay C, Giroud P, Berland M, Smart I, Kennedy H (1993) Modulation of the cell cycle contributes to the parcellation of the primate visual cortex. Nature 366:464-466.
    • (1993) Nature , vol.366 , pp. 464-466
    • Dehay, C.1    Giroud, P.2    Berland, M.3    Smart, I.4    Kennedy, H.5
  • 16
    • 0024453042 scopus 로고
    • Immunocytochemical detection of 5- bromodeoxyuridine incorporation in the central nervous system of the mouse
    • del Rio JA, Soriano E (1989) Immunocytochemical detection of 5- bromodeoxyuridine incorporation in the central nervous system of the mouse. Brain Res Dev Brain Res 49:311-317.
    • (1989) Brain Res Dev Brain Res , vol.49 , pp. 311-317
    • del Rio, J.A.1    Soriano, E.2
  • 18
    • 0011870742 scopus 로고
    • Dose effects of bromodeoxyuridine (BRUD) on rodent hepatocyte proliferation measurements
    • Goldsworthy TL, Dunn CS, Popp JA (1992) Dose effects of bromodeoxyuridine (BRUD) on rodent hepatocyte proliferation measurements. Toxicologist 12:265.
    • (1992) Toxicologist , vol.12 , pp. 265
    • Goldsworthy, T.L.1    Dunn, C.S.2    Popp, J.A.3
  • 19
    • 0019903249 scopus 로고
    • Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication
    • Gratzner HG (1982) Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: a new reagent for detection of DNA replication. Science 218:474-475.
    • (1982) Science , vol.218 , pp. 474-475
    • Gratzner, H.G.1
  • 20
    • 0033953694 scopus 로고    scopus 로고
    • Exploiting the dynamics of S-phase tracers in developing brain: Interkinetic nuclear migration for cells entering versus leaving the S-phase
    • Hayes NL, Nowakowski RS (2000) Exploiting the dynamics of S-phase tracers in developing brain: interkinetic nuclear migration for cells entering versus leaving the S-phase. Dev Neurosci 22:44-55.
    • (2000) Dev Neurosci , vol.22 , pp. 44-55
    • Hayes, N.L.1    Nowakowski, R.S.2
  • 21
    • 0037204597 scopus 로고    scopus 로고
    • Dynamics of cell proliferation in the adult dentate gyrus of two inbred strains of mice
    • Hayes NL, Nowakowski RS (2002) Dynamics of cell proliferation in the adult dentate gyrus of two inbred strains of mice. Brain Res Dev Brain Res 134:77-85.
    • (2002) Brain Res Dev Brain Res , vol.134 , pp. 77-85
    • Hayes, N.L.1    Nowakowski, R.S.2
  • 22
    • 80054734616 scopus 로고
    • Mechanisms of action of purine and pyrimidine analogs
    • Brodsky I, Kahn S, Moyer J, New York: Grune and Stratton
    • Hitchings G, Elion G (1967) Mechanisms of action of purine and pyrimidine analogs. In: Cancer chemotherapy, I (Brodsky I, Kahn S, Moyer J, eds), p 26. New York: Grune and Stratton.
    • (1967) Cancer Chemotherapy, I , pp. 26
    • Hitchings, G.1    Elion, G.2
  • 23
    • 0000961718 scopus 로고
    • Effect of 5-bromodeoxyuridine on mamalian chromosomes
    • Hsu TC, Somers CE (1961) Effect of 5-bromodeoxyuridine on mamalian chromosomes. Proc Natl Acad Sci U S A 47:396-403.
    • (1961) Proc Natl Acad Sci U S A , vol.47 , pp. 396-403
    • Hsu, T.C.1    Somers, C.E.2
  • 24
    • 0033559869 scopus 로고    scopus 로고
    • Embryonic and postnatal injections of bromodeoxyuridine produce age-dependent morphological and behavioral abnormalities
    • Kolb B, Pedersen B, Ballermann M, Gibb R, Whishaw IQ (1999) Embryonic and postnatal injections of bromodeoxyuridine produce age-dependent morphological and behavioral abnormalities. J Neurosci 19:2337-2346.
    • (1999) J Neurosci , vol.19 , pp. 2337-2346
    • Kolb, B.1    Pedersen, B.2    Ballermann, M.3    Gibb, R.4    Whishaw, I.Q.5
  • 25
    • 0032477722 scopus 로고    scopus 로고
    • Changes in cell-cycle kinetics during the development and evolution of primate neocortex
    • Kornack DR, Rakic P (1998) Changes in cell-cycle kinetics during the development and evolution of primate neocortex. Proc Natl Acad Sci U S A 95:1242-1246.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 1242-1246
    • Kornack, D.R.1    Rakic, P.2
  • 27
    • 34447324614 scopus 로고    scopus 로고
    • The evaluation of early embryonic neurogenesis after exposure to the genotoxic agent 5-bromo- 2-deoxyuridine in mice
    • Kuwagata M, Ogawa T, Nagata T, Shioda S (2007) The evaluation of early embryonic neurogenesis after exposure to the genotoxic agent 5-bromo- 2-deoxyuridine in mice. Neurotoxicology 28:780-789.
    • (2007) Neurotoxicology , vol.28 , pp. 780-789
    • Kuwagata, M.1    Ogawa, T.2    Nagata, T.3    Shioda, S.4
  • 30
    • 70349820060 scopus 로고    scopus 로고
    • Thymidine analog methods for studies of adult neurogenesis are not equally sensitive
    • Leuner B, Glasper ER, Gould E (2009) Thymidine analog methods for studies of adult neurogenesis are not equally sensitive. J Comp Neurol 517:123-133.
    • (2009) J Comp Neurol , vol.517 , pp. 123-133
    • Leuner, B.1    Glasper, E.R.2    Gould, E.3
  • 31
    • 0023682977 scopus 로고
    • Use of bromodeoxyuridine-immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system
    • Miller MW, Nowakowski RS (1988) Use of bromodeoxyuridine-immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system. Brain Res 457:44-52.
    • (1988) Brain Res , vol.457 , pp. 44-52
    • Miller, M.W.1    Nowakowski, R.S.2
  • 32
    • 0025772038 scopus 로고
    • Effect of prenatal exposure to ethanol on the cell cycle kinetics and growth fraction in the proliferative zones of fetal rat cerebral cortex
    • Miller MW, Nowakowski RS (1991) Effect of prenatal exposure to ethanol on the cell cycle kinetics and growth fraction in the proliferative zones of fetal rat cerebral cortex. Alcohol Clin Exp Res 15:229-232.
    • (1991) Alcohol Clin Exp Res , vol.15 , pp. 229-232
    • Miller, M.W.1    Nowakowski, R.S.2
  • 33
    • 0025861765 scopus 로고
    • The genetic toxicology of 5-bromodeoxyuridine in mammalian cells
    • Morris SM (1991) The genetic toxicology of 5-bromodeoxyuridine in mammalian cells. Mutat Res 258:161-188.
    • (1991) Mutat Res , vol.258 , pp. 161-188
    • Morris, S.M.1
  • 34
    • 0034607499 scopus 로고    scopus 로고
    • New neurons: Extraordinary evidence or extraordinary conclusion?
    • Nowakowski RS, Hayes NL (2000) New neurons: extraordinary evidence or extraordinary conclusion? Science 288:771.
    • (2000) Science , vol.288 , pp. 771
    • Nowakowski, R.S.1    Hayes, N.L.2
  • 35
    • 84989436544 scopus 로고
    • Clearance rate of exogenous 3H-thymidine from the plasma of pregnant rhesus monkeys
    • Nowakowski RS, Rakic P (1974) Clearance rate of exogenous 3H-thymidine from the plasma of pregnant rhesus monkeys. Cell Tissue Kinet 7: 189-194.
    • (1974) Cell Tissue Kinet , vol.7 , pp. 189-194
    • Nowakowski, R.S.1    Rakic, P.2
  • 36
    • 0018679456 scopus 로고
    • The mode of migration of neurons to the hippocampus: A Golgi and electron microscopic analysis in foetal rhesus monkey
    • Nowakowski RS, Rakic P (1979) The mode of migration of neurons to the hippocampus: a Golgi and electron microscopic analysis in foetal rhesus monkey. J Neurocytol 8:697-718.
    • (1979) J Neurocytol , vol.8 , pp. 697-718
    • Nowakowski, R.S.1    Rakic, P.2
  • 37
    • 0016829560 scopus 로고
    • The correlation of the time of origin of neurons with their axonal projection: The combined use of [3H]thymidine autoradiography and horseradish peroxidase histochemistry
    • Nowakowski RS, LaVail J, Rakic P (1975) The correlation of the time of origin of neurons with their axonal projection: the combined use of [3H]thymidine autoradiography and horseradish peroxidase histochemistry. Brain Res 99:343-348.
    • (1975) Brain Res , vol.99 , pp. 343-348
    • Nowakowski, R.S.1    Lavail, J.2    Rakic, P.3
  • 38
    • 0024369746 scopus 로고
    • Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population
    • Nowakowski RS, Lewin SB, Miller W (1989) Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population. J Neurocytol 18:311-318.
    • (1989) J Neurocytol , vol.18 , pp. 311-318
    • Nowakowski, R.S.1    Lewin, S.B.2    Miller, W.3
  • 39
    • 0015782960 scopus 로고
    • Incorporation of thymidine and its analogue, bromodeoxyuridine, into embryos and maternal tissues of the mouse
    • Packard DS Jr, Menzies RA, Skalko RG (1973) Incorporation of thymidine and its analogue, bromodeoxyuridine, into embryos and maternal tissues of the mouse. Differentiation 1:397-404.
    • (1973) Differentiation , vol.1 , pp. 397-404
    • Packard Jr., D.S.1    Menzies, R.A.2    Skalko, R.G.3
  • 42
    • 0015923979 scopus 로고
    • Kinetics of proliferation and latency between final cell division and onset of differentiation of cerebellar stellate and basket neurons
    • Rakic P (1973) Kinetics of proliferation and latency between final cell division and onset of differentiation of cerebellar stellate and basket neurons. J Comp Neurol 147:523-546.
    • (1973) J Comp Neurol , vol.147 , pp. 523-546
    • Rakic, P.1
  • 43
    • 0015965793 scopus 로고
    • Neurons in rhesus monkey visual cortex: Systematic relation between time of origin and eventual disposition
    • Rakic P (1974) Neurons in rhesus monkey visual cortex: systematic relation between time of origin and eventual disposition. Science 183:425-427.
    • (1974) Science , vol.183 , pp. 425-427
    • Rakic, P.1
  • 44
    • 0017133560 scopus 로고
    • Prenatal genesis of connections subserving ocular dominance in the rhesus monkey
    • Rakic P (1976) Prenatal genesis of connections subserving ocular dominance in the rhesus monkey. Nature 261:467-471.
    • (1976) Nature , vol.261 , pp. 467-471
    • Rakic, P.1
  • 45
    • 0036358203 scopus 로고    scopus 로고
    • Neurogenesis in adult primate neocortex: An evaluation of the evidence
    • Rakic P (2002a) Neurogenesis in adult primate neocortex: an evaluation of the evidence. Nat Rev Neurosci 3:65-71.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 65-71
    • Rakic, P.1
  • 46
    • 0036469278 scopus 로고    scopus 로고
    • Adult neurogenesis in mammals: An identity crisis
    • Rakic P (2002b) Adult neurogenesis in mammals: an identity crisis. J Neurosci 22:614-618.
    • (2002) J Neurosci , vol.22 , pp. 614-618
    • Rakic, P.1
  • 47
    • 0036063708 scopus 로고    scopus 로고
    • Pre- and post-developmental neurogenesis in primates
    • Rakic P (2002c) Pre- and post-developmental neurogenesis in primates. Clin Neurosci Res 2:29-39.
    • (2002) Clin Neurosci Res , vol.2 , pp. 29-39
    • Rakic, P.1
  • 48
    • 0014273635 scopus 로고
    • Supravital DNA synthesis in the developing human and mouse brain
    • Rakic P, Sidman RL (1968) Supravital DNA synthesis in the developing human and mouse brain. J Neuropathol Exp Neurol 27:246-276.
    • (1968) J Neuropathol Exp Neurol , vol.27 , pp. 246-276
    • Rakic, P.1    Sidman, R.L.2
  • 49
    • 0014835132 scopus 로고
    • Histogenesis of cortical layers in human cerebellum, particularly the lamina dissecans
    • Rakic P, Sidman RL (1970) Histogenesis of cortical layers in human cerebellum, particularly the lamina dissecans. J Comp Neurol 139:473-500.
    • (1970) J Comp Neurol , vol.139 , pp. 473-500
    • Rakic, P.1    Sidman, R.L.2
  • 50
    • 0029127736 scopus 로고
    • Variability and partial synchrony of the cell cycle in the germinal zone of the early embryonic cerebral cortex
    • Reznikov K, van der Kooy D (1995) Variability and partial synchrony of the cell cycle in the germinal zone of the early embryonic cerebral cortex. J Comp Neurol 360:536-554.
    • (1995) J Comp Neurol , vol.360 , pp. 536-554
    • Reznikov, K.1    van der Kooy, D.2
  • 51
    • 0004285613 scopus 로고
    • Analogues of nucleic acid components. New York: Springer, Amsterdam: Elsevier. Roy-Burman P
    • Rogers AW (1973) Techniques of autoradiography. Amsterdam: Elsevier. Roy-Burman P (1970) Analogues of nucleic acid components. New York: Springer.
    • (1973) Techniques of Autoradiography , pp. 1970
    • Rogers, A.W.1
  • 52
    • 0022415192 scopus 로고
    • Strand breaks arising from the repair of the 5-bromodeoxyuridine- substituted template and methyl methanesulphonateinduced lesions can explain the formation of sister chromatid exchanges
    • Saffhill R, OckeyCH (1985) Strand breaks arising from the repair of the 5-bromodeoxyuridine- substituted template and methyl methanesulphonateinduced lesions can explain the formation of sister chromatid exchanges. Chromosoma 92:218-224.
    • (1985) Chromosoma , vol.92 , pp. 218-224
    • Saffhill, R.1
  • 53
    • 0016426501 scopus 로고
    • An autoradiographic study of the time of origin and the pattern of granule cell migration in the dentate gyrus of the rat
    • Schlessinger AR, Cowan WM, Gottlieb DI (1975) An autoradiographic study of the time of origin and the pattern of granule cell migration in the dentate gyrus of the rat. J Comp Neurol 159:149-175.
    • (1975) J Comp Neurol , vol.159 , pp. 149-175
    • Schlessinger, A.R.1    Cowan, W.M.2    Gottlieb, D.I.3
  • 54
    • 0742287870 scopus 로고    scopus 로고
    • Bromodeoxyuridine administered during neurogenesis of the projection neurons causes cerebellar defects in rat
    • Sekerkova ́ G, Ilijic E, Mugnaini E (2004) Bromodeoxyuridine administered during neurogenesis of the projection neurons causes cerebellar defects in rat. J Comp Neurol 470:221-239.
    • (2004) J Comp Neurol , vol.470 , pp. 221-239
    • Sekerková, G.1    Ilijic, E.2    Mugnaini, E.3
  • 56
    • 84984124167 scopus 로고
    • Autoradiographic Methods and Principles For Study of the Nervous System With Thymidine
    • New York: Springer
    • Sidman RL (1970) Autoradiographic methods and principles for study of the nervous system with thymidine- 3H. New York: Springer.
    • (1970)
    • Sidman, R.L.1
  • 57
    • 0000879018 scopus 로고
    • Cell proliferation and migration in the primitive ependymal zone: An autoradiographic study of histogenesis in the nervous system
    • Sidman RL, Miale IL, Feder N (1959) Cell proliferation and migration in the primitive ependymal zone: an autoradiographic study of histogenesis in the nervous system. Exp Neurol 1:322-333.
    • (1959) Exp Neurol , vol.1 , pp. 322-333
    • Sidman, R.L.1    Miale, I.L.2    Feder, N.3
  • 58
    • 0029052830 scopus 로고
    • Early ontogeny of the secondary proliferative population of the embryonic murine cerebral wall
    • Takahashi T, Nowakowski RS, Caviness VS Jr (1995) Early ontogeny of the secondary proliferative population of the embryonic murine cerebral wall. J Neurosci 15:6058-6068.
    • (1995) J Neurosci , vol.15 , pp. 6058-6068
    • Takahashi, T.1    Nowakowski, R.S.2    Caviness Jr., V.S.3
  • 59
    • 33845209203 scopus 로고    scopus 로고
    • BrdU immunohistochemistry for studying adult neurogenesis: Paradigms, pitfalls, limitations, and validation
    • Taupin P (2007) BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation. Brain Res Rev 53:198-214.
    • (2007) Brain Res Rev , vol.53 , pp. 198-214
    • Taupin, P.1
  • 60
    • 0015505111 scopus 로고
    • Generation times of the matrix cells during embryonic brain development: An autoradiographic study in rats
    • von Waechter R, Jaensch B (1972) Generation times of the matrix cells during embryonic brain development: an autoradiographic study in rats. Brain Res 46:235-250.
    • (1972) Brain Res , vol.46 , pp. 235-250
    • von Waechter, R.1    Jaensch, B.2
  • 61
    • 0015621792 scopus 로고
    • Effect of fluorodeoxyuridine, colcemid, and bromodeoxyuridine on developing neocortex of the mouse
    • Webster W, Shimada M, Langman J (1973) Effect of fluorodeoxyuridine, colcemid, and bromodeoxyuridine on developing neocortex of the mouse. Am J Anat 137:67-85.
    • (1973) Am J Anat , vol.137 , pp. 67-85
    • Webster, W.1    Shimada, M.2    Langman, J.3
  • 62
    • 0035871660 scopus 로고    scopus 로고
    • DNA replication precedes neuronal cell death in Alzheimer's disease
    • Yang Y, Geldmacher DS, Herrup K (2001) DNA replication precedes neuronal cell death in Alzheimer's disease. J Neurosci 21:2661-2668.
    • (2001) J Neurosci , vol.21 , pp. 2661-2668
    • Yang, Y.1    Geldmacher, D.S.2    Herrup, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.