Ketogenic diet for intractable childhood epilepsy;Ketogene Diät bei refraktärer Epilepsie im Kindesalter

Monatsschrift fur Kinderheilkunde

Volumn 159, Issue 8, 2011, Pages 739-744

  Klepper, J ^a   Leiendecker, B ^b  

^a KLINIKUM ASCHAFFENBURG   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Epilepsy; GLUT1 deficiency syndrome; Ketogenic diet; Pyruvate dehydrogenase deficiency; Refractory

Indexed keywords

GLUCOSE TRANSPORTER 1; PYRUVATE DEHYDROGENASE;

ARTICLE; BENIGN CHILDHOOD EPILEPSY; BRAIN METABOLISM; ENERGY METABOLISM; HUMAN; INTRACTABLE EPILEPSY; KETOGENIC DIET; LIPID DIET; LOW CARBOHYDRATE DIET; PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY; TREATMENT INDICATION; VAGUS NERVE STIMULATION;

EID: 80054725735     PISSN: 00269298     EISSN: 14330474     Source Type: Journal    
DOI: 10.1007/s00112-011-2396-4     Document Type: Article

References (27)

1. Bough KJ, Rho JM (2007) Anticonvulsant mechanisms of the ketogenic diet. Epilepsia 48:43-58 (Pubitemid 46096022)
2. Caraballo RH, Cersosimo RO, Sakr D et al (2006) Ke-togenic diet in patients with myoclonic-astatic epilepsy. Epileptic Disord 8:151-155 (Pubitemid 44013158)
3. Cross JH, McLellan A, Neal EG et al (2010) The ke-togenic diet in childhood epilepsy: where are we now? Arch Dis Child 95:550-553
4. Deutsche Gesellschaft für Ernährung (DGE) (Hrsg) (1991) Empfehlungen für die Nährstoffzufuhr. Umschau, Frankfurt am Main
5. Gasior M, Rogawski MA, Hartman AL (2006) Neu-roprotective and disease-modifying effects of the ketogenic diet. Behav Pharmacol 17:431-439 (Pubitemid 44325805)
6. Gilbert DL, Pyzik PL, Vining E P, Freeman JM (1999) Medication cost reduction in children on the keto-genic diet: data from a prospective study. J Child Neurol 14:469-471 (Pubitemid 29352579)
7. Henderson CB, Filloux FM, Alder SC et al (2006) Efficacy of the ketogenic diet as a treatment option for epilepsy: meta-analysis. J Child Neurol 21:193-198 (Pubitemid 43891143)
8. Kang HC, Lee YM, Kim HD et al (2007) Safe and effective use of the ketogenic diet in children with epilepsy and mitochondrial respiratory chain complex defects. Epilepsia 48:82-88 (Pubitemid 46096027)
9. Kinderen RJ de, Lambrechts DA, Postulart D et al (2011) Research into the (cost-) effectiveness of the ketogenic diet among children and adolescents with intractable epilepsy: design of a randomized controlled trial. BMC Neurol 11:10
10. Klepper J (2008) Glucose transporter deficiency syndrome (GLUT1DS) and the ketogenic diet. Epi-lepsia 49:46-49
11. Klepper J, Baumeister AM (2003) Leitlinie zur Anwendung der ketogenen Diät im Kindesalter. Gesellschaft für Neuropädiatrie, Berlin, http://www. neuropaediatrie.com
12. Klepper J, Scheffer H, Leiendecker B et al (2005) Seizure control and acceptance of the ketogenic diet in GLUT1 deficiency syndrome: a 2- to 5-year follow-up of 15 children enrolled prospectively. Neuropediatrics 36:302-308 (Pubitemid 41501116)
13. Kossoff EH, Dorward JL (2008) The modified Atkins diet. Epilepsia [Suppl 8] 49:37-41
14. Kossoff EH, McGrogan JR (2005) Worldwide use of the ketogenic diet. Epilepsia 46:280-289 (Pubitemid 40194672)
15. Kossoff EH, Zupec-Kania BA, Amark PE et al (2009) Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group. Epilepsia 50:304-317
16. Kwan P, Brodie MJ (2000) Early identification of refractory epilepsy. N Engl J Med 342:314-319 (Pubitemid 30075244)
17. Nabbout R, Mazzuca M, Hubert P et al (2010) Efficacy of ketogenic diet in severe refractory status epilepticus initiating fever induced refractory epileptic encephalopathy in school age children (FIRES). Epilepsia 51:2033-2037
18. Neal EG, Chaffe H, Schwartz RH et al (2008) The ke-togenic diet for the treatment of childhood epilepsy: a randomised controlled trial. Lancet Neurol 7:500-506
19. Neal EG, Chaffe H, Schwartz RH et al (2009) A randomized trial of classical and medium-chain triglyceride ketogenic diets in the treatment of childhood epilepsy. Epilepsia 50:1109-1117
20. Nordli DR Jr, Kuroda MM, Carroll J et al (2001) Experience with the ketogenic diet in infants. Pediatrics 108:129-133 (Pubitemid 32592016)
21. Pellock JM, Hrachovy R, Shinnar S et al (2010) Infantile spasms: a U.S. consensus report. Epilepsia 51:2175-2189
22. Pfeifer HH, Thiele EA (2005) Low-glycemic-index treatment: a liberalized ketogenic diet for treatment of intractable epilepsy. Neurology 65:1810-1812
23. Shinnar S, Pellock JM (2002) Update on the epidemiology and prognosis of pediatric epilepsy. J Child Neurol 17:S4-S17 (Pubitemid 34460806)
24. Veech RL, Chance B, Kashiwaya Y et al (2001) Keto-ne bodies, potential therapeutic uses. IUBMB Life 51:241-247 (Pubitemid 32848155)
25. Veggiotti P, Burlina A, Coppola G et al (2011) The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: an Italian consensus. Epi-lepsia [Suppl 2] 52:83-89
26. Wallace DC, Fan W, Procaccio V (2010) Mitochon-drial energetics and therapeutics. Annu Rev Pathol 5:297-348
27. Wexler ID, Hemalatha SG, McConnell J et al (1997) Outcome of pyruvate dehydrogenase deficiency treated with ketogenic diets. Neurology 49:1655-1661