Nelfinavir and its active metabolite, hydroxy-t-butylamidenelfinavir (M8), are transferred in small quantities to breast milk and do not reach biologically significant concentrations in breast-feeding infants whose mothers are taking nelfinavir

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 11, 2011, Pages 5168-5171

  Weidle, Paul J ^a,e   Zeh, Clement ^a,b,f   Martin, Amy ^a   Lando, Richard ^b,f   Angira, Frank ^b,f   Osoga, Joseph ^b,f   Ogindo, Paul ^b,f   Girde, Sonali ^a,c,d,e   Minniear, Timothy D ^a   Thomas, Timothy K ^a,g  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^c NORTHROP GRUMMAN CORPORATION   (United States)

^d ICF INTERNATIONAL   (United States)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^f Centers for Disease Control and Prevention Kenya   (Kenya)

^g NATL CENTER FOR INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; HYDROXY T BUTYLAMIDENELFINAVIR; NELFINAVIR; UNCLASSIFIED DRUG;

ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; BREAST FEEDING; BREAST MILK; DELIVERY; DRUG BLOOD LEVEL; DRUG METABOLISM; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MATERNAL PLASMA; NEWBORN; PERINATAL PERIOD; PRIORITY JOURNAL; VERTICAL TRANSMISSION;

ADULT; ANTI-HIV AGENTS; BREAST FEEDING; FEMALE; HUMANS; MILK, HUMAN; NELFINAVIR; PREGNANCY; YOUNG ADULT;

EID: 80054703113     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.05273-11     Document Type: Article

References (12)

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