Screening for diabetes using an oral glucose tolerance test within a western multi-ethnic population identifies modifiable cardiovascular risk: The ADDITION-Leicester study

Diabetologia

Volumn 54, Issue 9, 2011, Pages 2237-2246

  Webb, D R ^a   Gray, L J ^b   Khunti, K ^b   Srinivasan, B ^a   Taub, N ^b   Campbell, S ^a   Barnett, J ^a   Farooqi, A ^b   Echouffo Tcheugui, J B ^c   Griffin, S J ^c   Wareham, N J ^c   Davies, M J ^a  

^a LEICESTER ROYAL INFIRMARY   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

ADDITION Leicester; Cardiovascular disease; Multi ethnic; Screening; South Asian; Type 2 diabetes

Indexed keywords

GLUCOSE;

ADULT; AGE; AGED; ARTICLE; ASIAN; CARDIOVASCULAR RISK; CAUCASIAN; CONTROLLED STUDY; DISORDERS OF CARBOHYDRATE METABOLISM; ETHNIC GROUP; FEMALE; FRAMINGHAM RISK SCORE; GENDER; GENERAL PRACTICE; HEART PROTECTION; HUMAN; IMPAIRED FASTING GLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; MALE; MASS SCREENING; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PREVALENCE; PRIORITY JOURNAL; RANDOM SAMPLE; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK REDUCTION; SINGLE BLIND PROCEDURE; WESTERN HEMISPHERE;

ADULT; AGED; ASIA; BLOOD GLUCOSE; CARDIOVASCULAR DISEASES; DIABETES MELLITUS, TYPE 2; EUROPE; FEMALE; GLUCOSE TOLERANCE TEST; GREAT BRITAIN; HUMANS; LONGITUDINAL STUDIES; MALE; MASS SCREENING; MIDDLE AGED; PREVALENCE; RISK FACTORS;

EID: 80054701712     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2189-2     Document Type: Article

References (50)

1. Sandbaek A, Griffin SJ, Rutten G et al (2008) Stepwise screening for diabetes identifies people with high but modifiable coronary heart disease risk. The ADDITION study. Diabetologia 51:1127-1134
2. Duckworth W, Abraira C, Moritz T et al (2009) Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 360:129-139
3. The ADVANCE, Collaborative G (2008) Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 358:2560-2572
4. Waugh N, Scotland G, McNamee P (2007) Screening for type 2 diabetes: literature review and economic modelling. Health Technology Assessment 11: iii-iv, ix-xi, 1-125
5. Department of Health (2009) Putting prevention first. NHS Health Check: vascular risk assessment and management. Gateway Reference 11473. Available from www.dh.gov.uk/prod-consum-dh/groups/dh-digitalassets/documents/digitalasset/dh- 098410.pdf. Accessed 1 April 2011
6. Department of Health (1998) RCGP summary paper: first report of the National Screening Committee. DoH, London
7. Riste L, Khan F, Cruickshank K (2001) High prevalence of type 2 diabetes in all ethnic groups, including Europeans, in a British inner city: relative poverty, history, inactivity, or 21st century Europe? Diabetes Care 24:1377-1383 (Pubitemid 33716424)
8. Forouhi NG, Merrick D, Goyder E et al (2006) Diabetes prevalence in England, 2001-estimates from an epidemiological model. Diabet Med 23:189-197
9. Lauritzen T, Griffin S, Borch-Johnsen K, Wareham NJ, Wolf-fenbuttel BHR, Rutten G (2000) The ADDITION study: proposed trial of the cost-effectiveness of an intensive multifactorial intervention on morbidity and mortality among people type 2 diabetes detected by screening. Int J Obes 24(Suppl 3):S6-S11
10. Gaede P, Vedel P, Larsen N, Jensen GVH, Parving H-, Pedersen O (2003) Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med 348:383-393 (Pubitemid 36159355)
11. Griffin SJ, Borch-Johnsen K, Wareham NJ, et al (2011) A randomised trial of the effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with screen-detected type 2 diabetes: the ADDITION-Europe study. Lancet (in press)
12. Webb D, Khunti K, Srinivasan B et al (2010) Rationale and design of the ADDITION-Leicester study, a systematic screening programme and randomised controlled trial of multi-factorial cardiovascular risk intervention in people with type 2 diabetes mellitus detected by screening. BMC Trials 11:16
13. Khunti K, Kumar S, Brodie J (2009) Diabetes UK and South Asian Health Foundation Recommendations on Diabetes Research Priorities for British South Asians, 1st edn. Diabetes UK, London
14. Mason S, Hussain-Gambles M, Leese B, Atkin K, Brown J (2003) Representation of South Asian people in randomised clinical trials: analysis of trials' data. BMJ 326:1244-1245 (Pubitemid 36688081)
15. Gray LJ, Tringham JR, Davies MJ et al (2010) Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: a cross-sectional study. Vasc Health Risk Manage 6:837-842
16. Communities and Local Government (2007) The English Indices of Deprivation 2004 (revised). Available from www.communities.gov.uk/publications/ communities/englishindices. Accessed 1 April 2011
17. Alberti KGMM, Zimmet PZ (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med 15:539-553 (Pubitemid 28319935)
18. Brindle P, May M, Gill P et al (2006) Primary prevention of cardiovascular disease: a web-based risk score for seven British black and minority ethnic groups. Heart 92:1595-1602 (Pubitemid 44629163)
19. Kothari V, Stevens RJ, Adler AI, Stratton IM, Manley SE, Andrew Neil H et al (2002) UKPDS 60: risk of stroke in type 2 diabetes estimated by the UK Prospective Diabetes Study risk engine. Stroke 33:1776-1781 (Pubitemid 34761059)
20. Stevens RJ, Kothari V, Adler AI, Stratton IM, Holman RR (2001) The UKPDS risk engine: a model for the risk of coronary heart disease in type II diabetes (UKPDS 56). Clin Sci 101:671-679 (Pubitemid 33135349)
21. Echouffo-Tcheugui JB, Sargeant LA, Prevost AT et al (2008) How much might cardiovascular disease risk be reduced by intensive therapy in people with screen-detected diabetes? Diabet Med 25:1433-1439
22. Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HAW (2008) 10-Year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 359:1577-1589
23. Antithrombotic Trialists' (ATT) Collaboration (2009) Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet 373:1849-1860
24. Holman RR, Haffner SM, McMurray JJ et al (2010) Effect of nateglinide on the incidence of diabetes and cardiovascular events. N Engl J Med 362:1463-1476
25. UK Prospective Diabetes Study Group (1998) Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 317:703-713
26. UK Prospective Diabetes Study (UKPDS) study group (1998) Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352:837-853
27. Antithrombotic Trialists' (ATT) Collaboration (2002) Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 324:71-86
28. Heart Protection Study Collaborative Group (2003) MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5,963 people with diabetes: randomised placebo-controlled trial. Lancet 361:2005-2016
29. Colhoun HM, Betteridge DJ, Durrington PN et al (2004) Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet 364:685-696 (Pubitemid 39140624)
30. Califf RM, McMurray JJ, Holman RR et al (2010) Effect of valsartan on the incidence of diabetes and cardiovascular events. N Engl J Med 362:1477-1490
31. Craig CL, Marshall AL, Sjostrom M et al (2003) International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 35:1381-1395 (Pubitemid 36936159)
32. Lawrence JM, Bennett P, Young A, Robinson AM (2001) Screening for diabetes in general practice: cross sectional population study. BMJ 323:548-551 (Pubitemid 32835576)
33. Christensen JO, Sandbaek A, Lauritzen T, Borch-Johnsen K (2004) Population-based stepwise screening for unrecognised Type 2 diabetes is ineffective in general practice despite reliable algorithms. Diabetologia 47:1566-1573 (Pubitemid 39371639)
34. Janssen PG, Gorter KJ, Stolk RP, Akarsubasi M, Rutten GE (2009) Three years follow-up of screen-detected diabetic and nondiabetic subjects: who is better off? The ADDITION Netherlands study. BMC Fam Pract 9:67
35. Spijkerman AM, Adriaanse MC, Dekker JM et al (2002) Diabetic patients detected by population-based stepwise screening already have a diabetic cardiovascular risk profile. Diabetes Care 25:1784-1789 (Pubitemid 41071087)
36. Sargent LA, Simmons RK, Barling RS et al (2010) Who attends a UK diabetes screening programme? Findings from the ADDITION-Cambridge study. Diabet Med 27:995-1003
37. Bullimore SP, Keyworth C (1997) Finding diabetics-a method of screening in general practice. Br J Gen Pract 47:371-373 (Pubitemid 27254717)
38. Joshi P, Islam S, Pais P et al (2007) Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. J Am Med Assoc 297:286-294 (Pubitemid 46143306)
39. Samanta A, Burden AC, Fent B (1987) Comparative prevalence of non-insulin-dependent diabetes mellitus in Asian and white Caucasian adults. Diab Res Clin Pract 4:1-6 (Pubitemid 17152021)
40. NHS: The Information Centre (2006) Health survey for England 2004: health of ethnic minorities-full report. Available from www.ic.nhs.uk/pubs/ hse04ethnic. Accessed 1 April 2011
41. Department of Health (2004) Quality and Outcomes Framework (QoF): guidance. Department of Health, London
42. McKeigue PM, Shah B, Marmot MG (1991) Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet 337:382-386
43. McKeigue PM, Ferrie JE, Pierpoint T, Marmot MG (1993) Association of early-onset coronary heart disease in South Asian men with glucose intolerance and hyperinsulinemia. Circulation 87:152-161 (Pubitemid 23019345)
44. Forouhi NG, Sattar N, Tillin T, McKeigue PM, Chaturvedi N (2006) Do known risk factors explain the higher coronary heart disease mortality in South Asian compared with European men? Prospective follow-up of the Southall and Brent studies, UK. Diabetologia 49:2580-2588
45. Bhopal R, Unwin N, White M et al (1999) Heterogeneity of coronary heart disease risk factors in Indian, Pakistani, Bangladeshi, and European origin populations: cross sectional study. BMJ 319:215-220 (Pubitemid 29338688)
46. Gholap N, Davies MJ, Patel K, Sattar N, Khunti K (2011) Type 2 diabetes mellitus and cardiovascular disease in South Asians. Prim Care Diab. doi:10.1016/j.pcd.2010.08.002
47. Jorgensen T, Borch-Johnsen K, Thomsen TF, Ibsen H, Glumer C, Pisinger C (2003) A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99. Eur J Cardiovasc Prev Rehabil 10:377-386 (Pubitemid 38037253)
48. de Vegt F, Dekker JM, Ruhe HG et al (1999) Hyperglycaemia is associated with all-cause and cardiovascular mortality in the Hoorn population: the Hoorn study. Diabetologia 42:926-931 (Pubitemid 29369599)
49. Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393-403 (Pubitemid 34437694)
50. Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, Laakso M (2003) Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial. J Am Med Assoc 290:486-494 (Pubitemid 37430502)