Detection of the staphylococcal multiresistance gene cfr in Proteus vulgaris of food animal origin

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 11, 2011, Pages 2521-2526

  Wang, Yu ^a   Wang, Yang ^a   Wu, Cong Ming ^a   Schwarz, Stefan ^b   Shen, Zhangqi ^c   Zhang, Wanjiang ^a   Zhang, Qijing ^c   Shen, Jian Zhong ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^c IOWA STATE UNIVERSITY   (United States)

Author keywords

Food safety; Inter genus transfer; Linezolid resistance; Reserve antibiotics

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; BACTERIAL PROTEIN; CEFTAZIDIME; CEFTIOFUR; CFR PROTEIN; CHLORAMPHENICOL; CIPROFLOXACIN; CLINDAMYCIN; DNA 16S; FIMD PROTEIN; FLOR PROTEIN; FLORFENICOL; GENTAMICIN; LINEZOLID; SULFAMETHOXAZOLE; TIAMULIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; BACTERIUM COLONY; BACTERIUM ISOLATE; CONTROLLED STUDY; DNA INTEGRATION; GENE INSERTION; GENE SEQUENCE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NOSE SMEAR; NUCLEOTIDE SEQUENCE; PLASMID; PROTEUS VULGARIS; SEQUENCE HOMOLOGY; STAPHYLOCOCCUS SCIURI;

ACETAMIDES; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BASE SEQUENCE; DNA TRANSPOSABLE ELEMENTS; DNA, RIBOSOMAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FIMBRIAE PROTEINS; FOOD MICROBIOLOGY; FOOD SAFETY; MICROBIAL SENSITIVITY TESTS; OXAZOLIDINONES; PROTEUS VULGARIS; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA; STAPHYLOCOCCUS; SUS SCROFA; THIAMPHENICOL;

EID: 80054699060     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr322     Document Type: Article

References (22)

1. Diekema DJ, Jones RN. Oxazolidinone antibiotics. Lancet 2001; 358: 1975-82.
2. Tsiodras S, Gold HS, Sakoulas G et al. Linezolid resistance in a clinical isolate of Staphylococcus aureus. Lancet 2001; 358: 207-8.
3. Long KS, Poehlsgaard J, Kehrenberg C et al. The Cfr rRNA methyltransferase confers resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A antibiotics. Antimicrob Agents Chemother 2006; 50: 2500-5.
4. Smith LK, Mankin AS. Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. Antimicrob Agents Chemother 2008; 52: 1703-12.
5. Schwarz S, Werckenthin C, Kehrenberg C. Identification of a plasmid-borne chloramphenicol-florfenicol resistance gene in Staphylococcus sciuri. Antimicrob Agents Chemother 2000; 44: 2530-3.
6. Toh SM, Xiong L, Arias CA et al. Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid. Mol Microbiol 2007; 64: 1506-14.
7. Bonilla H, Huband MD, Seidel J et al. Multicity outbreak of linezolid-resistant Staphylococcus epidermidis associated with clonal spread of a cfr-containing strain. Clin Infect Dis 2010; 51: 796-800.
8. Morales G, Picazo JJ, Baos E et al. Resistance to linezolid is mediated by the cfr gene in the first report of an outbreak of linezolid-resistant Staphylococcus aureus. Clin Infect Dis 2010; 50: 821-5.
9. Jones RN, Ross JE, Bell JM et al. Zyvox Annual Appraisal of Potency and Spectrum program: linezolid surveillance program results for 2008. Diagn Microbiol Infect Dis 2009; 65: 404-13.
10. Mendes RE, Deshpande L, Rodriguez-Noriega E et al. First report of staphylococcal clinical isolates in Mexico with linezolid resistance caused by cfr: evidence of in vivo cfr mobilization. J Clin Microbiol 2010; 48: 3041-3.
11. Dai L, Wu CM, Wang MG et al. First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. Antimicrob Agents Chemother 2010; 54: 3953-5.
12. Zhang WJ, Wu CM, Wang Y et al. The new genetic environment of cfr on plasmid pBS-02 in a Bacillus strain. J Antimicrob Chemother 2011; 66: 1174-5.
13. Cloeckaert A, Baucheron S, Flaujac G et al. Plasmid-mediated florfenicol resistance encoded by the floR gene in Escherichia coli isolated from cattle. Antimicrob Agents Chemother 2000; 44: 2858-60.
14. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Twenty-first Informational Supplement M100-S21. CLSI, Wayne, PA, USA, 2011.
15. Zhang K, McClure JA, Elsayed S et al. Novel staphylococcal cassette chromosome mec type, tentatively designated type VIII, harboring class A mec and type 4 ccr gene complexes in a Canadian epidemic strain of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2009; 53: 531-40.
16. Kim TW, Kim YH, Kim SE et al. Identification and distribution of Bacillus species in doenjang by whole-cell protein patterns and 16S rRNA gene sequence analysis. J Microbiol Biotechnol 2010; 20: 1210-4.
17. Schenk S, Laddaga RA. Improved method for electroporation of Staphylococcus aureus. FEMS Microbiol Lett 1992; 73: 133-8.
18. Kadlec K, Schwarz S. Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. Antimicrob Agents Chemother 2009; 53: 3589-91.
19. Kehrenberg C, Aarestrup FM, Schwarz S. IS21-558 insertion sequences are involved in the mobility of the multiresistance gene cfr. Antimicrob Agents Chemother 2007; 51: 483-7.
20. Barberis-Maino L, Berger-Bächi B, Weber H et al. IS431, a staphylococcal insertion sequence-like element related to IS26 from Proteus vulgaris. Gene 1987; 59: 107-13.
21. Jones RN, Pfaller MA, Rhomberg PR et al. Tiamulin activity against fastidious and nonfastidious veterinary and human bacterial isolates: initial development of in vitro susceptibility test methods. J Clin Microbiol 2002; 40: 461-5.
22. Brickner SJ, Barbachyn MR, Hutchinson DK et al. Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections. J Med Chem 2008; 51: 1981-90.