Ex vivo susceptibility of Plasmodium falciparum isolates from Dakar, Senegal, to seven standard anti-malarial drugs

Malaria Journal

Volumn 10, Issue , 2011, Pages

  Fall, Bécaye ^a   Diawara, Silmane ^a   Sow, Kowry ^a   Baret, Eric ^b   Diatta, Bakary ^a   Fall, Khadidiatou B ^a   Mbaye, Pape S ^a   Fall, Fatou ^a   Diémé, Yaya ^a   Rogier, Christophe ^b   Wade, Boubacar ^a   Bercion, Raymond ^a   Pradines, Bruno ^b,c  

^a HÔPITAL PRINCIPAL DE DAKAR   (Senegal)

^b INSTITUT DE RECHERCHE BIOMÉDICALE DES ARMÉES   (France)

^c Centre National de Reference du Paludisme   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE PLUS ARTESUNATE; ANTIMALARIAL AGENT; ARTEMETHER PLUS BENFLUMETOL; BENFLUMETOL; CHLOROQUINE; DEETHYLAMODIAQUINE; DIHYDROARTEMISININ; DOXYCYCLINE; LACTATE DEHYDROGENASE; MEFLOQUINE; QUININE; PROTOZOAL PROTEIN;

ANTIMALARIAL DRUG RESISTANCE; ANTIMALARIAL DRUG SUSCEPTIBILITY; ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; HUMAN; HUMAN TISSUE; IC 50; MALARIA; OUTCOME ASSESSMENT; PARASITE ISOLATION; PLASMODIUM FALCIPARUM; PUBLIC HOSPITAL; SENEGAL; SEROPREVALENCE; DRUG EFFECT; DRUG SENSITIVITY; ISOLATION AND PURIFICATION; MALARIA FALCIPARUM; METHODOLOGY; PARASITOLOGY;

ANTIMALARIALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INHIBITORY CONCENTRATION 50; L-LACTATE DEHYDROGENASE; MALARIA, FALCIPARUM; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; SENEGAL;

EID: 80054695561     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-10-310     Document Type: Article

References (54)

1. Antimalarial drug resistance. Le Bras J, Musset L, Clain J, Med Mal Infect 2006 36 401 405 10.1016/j.medmal.2006.05.005 16854546 (Pubitemid 44425394)
2. Preventing antimalarial drug resistance through combinations. 2001. White NJ, Drug Resist Updat 2001 1 3 9
3. Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria. Eastman RT, Fidock DA, Nat Rev Microbiol 2009 7 864 874 19881520
4. Changes in the treatment responses to artesunate-mefloquine on the Northwestern border of Thailand during 13 years of continuous deployment. Carrara VI, Zwang J, Ashley EA, Price RN, Stepniewska K, Barends M, Brockman A, Anderson T, McGready R, Phaiphun L, Proux S, van Vugt M, Hutagalung R, Lwin KM, Phyo AP, Preechapornkul P, Imwong M, Pukrittayakamee S, Singhasivanon P, White NJ, Nosten F, PlosOne 2009 4 4451
5. Artemisinin resistance in Plasmodium falciparum malaria. Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, Lwin KM, Ariey F, Hanpithakpong W, Lee SJ, Ringwald P, Silamut K, Imwrong M, Chotivanish K, Lim P, Herdman T, An SS, Yeung S, Singhasivanon P, Day NPJ, Lindegardh N, Socheat D, White NJ, N Engl J Med 2009 361 455 467 10.1056/NEJMoa0808859 19641202
6. Evidence of artemisinin-resistant malaria in western Cambodia. Noedl H, Se Y, Schaecher K, Smith BL, Socheat D, Fukuda MM, N Engl J Med 2008 359 2619 2620 10.1056/NEJMc0805011 19064625
7. Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia. Rogers WO, Sem R, Tero T, Chim P, Lim P, Muth S, Socheat D, Ariey F, Wongsrichanalai C, Malar J 2009 8 10 10.1186/1475-2875-8-10 19138388
8. Selection of parasites with diminished drug susceptibility by amodiaquine-containing antimalarial regimens in Uganda. Nawaz F, Nsobya SL, Kiggundu M, Joloba M, Rosenthal PJ, J Infect Dis 2009 200 1650 1657 10.1086/647988 19905933
9. Malaria transmission in Dakar: a two-year survey. Pagès F, Texier G, Pradines B, Gadiaga L, Machault V, Jarjaval F, Penhoat K, Berger F, Trape JF, Rogier C, Sokhna C, Malar J 2008 7 178 10.1186/1475-2875-7-178 18796138
10. Highly focused anopheline breeding sites and malaria transmission in Dakar. Machault V, Gadiaga L, Vignolles C, Jarjaval F, Bouzid S, Sokhna C, Lacaux JP, Trape JF, Rogier C, Pagès F, Malar J 2009 8 138 10.1186/1475-2875-8-138 19552809
11. Spatial heterogeneity and temporal evolution of malaria transmission risk in Dakar, Senegal, according to remotely sensed environmental data. Machault V, Vignolles C, Pagès F, Gadiaga L, Gaye A, Sokhna C, Trape JF, Lacaux JP, Rogier C, Malar J 2010 9 252 10.1186/1475-2875-9-252 20815867
12. Place du paludisme dans un service de pathologie infectieuse Dakar (Sénégal). Soumaré M, Seydi M, Diop SA, Ba TA, Ndour CT, Dieng Y, Diop BM, Sow PS, Med Trop 2008 68 485 490 (Pubitemid 352791641)
13. Parasite polymorphism and severe malaria in Dakar (Senegal): a West African urban area. Bob NS, Diop BM, Rnaud F, Marrama L, Durand P, Tall A, Ka B, Ekala MT, Bouchier C, Mercereau-Puijalon O, Jambou R, PlosOne 2011 5 9817
14. Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial. Ndiaye JLA, Faye B, Gueye A, Tine R, Ndiaye D, Tchania C, Ndiaye I, Barry A, Cisse B, Lameyre V, Gaye O, Malar J 2011 10 237 10.1186/1475-2875-10-237 21838909
15. Efficacy and tolerability of four antimalarial combinations in the treatement of uncomplicated Plasmodium falciparum malaria in Senegal. Faye B, Ndiaye JL, Ndiaye D, Dieng Y, Faye O, Gaye O, Malar J 2007 6 80 10.1186/1475-2875-6-80 17570848 (Pubitemid 47064368)
16. A randomized trial of artesunate mefloquine versus artemether lumefantrine for the treatment of uncomplicated malaria in Senegalese children. Faye B, Ndiaye JL, Tine R, Sylla K, Gueye A, Colle Lô A, Gaye O, Am J Trop Med Hyg 2010 82 140 144 10.4269/ajtmh.2010.09-0265 20065010
17. Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria. Ndiaye JL, Faye B, Diouf AM, Kuété T, Cisse M, Seck PA, Brasseur P, Same-Ekobo A, Lameyre V, Gaye O, Malar J 2008 7 16 10.1186/1475-2875-7-16 18205945 (Pubitemid 351328665)
18. Randomized, multicentre assessment of the efficacy and safety of ASAQ-a fixed dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria. Ndiaye JL, Randrianarivelojosia M, Sagara I, Brasseur P, Ndiaye I, Faye B, Randrianasolo L, Ratsimbasoa A, Forlemu D, Ama Moor V, Traore A, Dicko Y, Dara N, Lameyre V, Diallo M, Djimdé A, Same-Ekobo A, Gaye O, Malar J 2009 8 125 10.1186/1475-2875-8-125 19505304
19. Prevalence of in vitro resistance to eleven standard or new antimalarial drugs among Plasmodium falciparum isolates from Pointe-Noire, Republic of the Congo. Pradines B, Hovette P, Fusai T, Atanda HL, Baret E, Cheval P, Mosnier J, Callec A, Cren J, Amalvict R, Gardair JP, Rogier C, J Clin Microbiol 2006 44 2404 2408 10.1128/JCM.00623-06 16825356 (Pubitemid 44092404)
20. Assessment of the drug susceptibility of Plasmodium falciparum clinical isolates from Africa using a Plasmodium lactate dehydrogenase immunodetection assay and an inhibitory maximum effect model for precise measurement of the 50-percent inhibitory concentration. Kaddouri H, Nakache S, Houzé S, Mentré F, Le Bras J, Antimicrob Agents Chemother 2006 50 3343 3349 10.1128/AAC.00367-06 17005815 (Pubitemid 44527508)
21. Baseline in vitro of efficacy of ACT component drug on Plasmodium falciparum clinical isolates from Mali. Kaddouri H, Djimdé A, Dama S, Kodio A, Tekete M, Hubert V, Koné A, Maiga H, Yattara O, Fofana B, Sidibe B, Sangaré CPO, Doumbo O, Le Bras J, Int J Parasitol 2008 38 791 798 10.1016/j.ijpara.2007.12.002 18249407
22. Synchronization of Plasmodium falciparum erythrocytic stages in culture. Lambros C, Vanderberg JP, J Parasitol 1979 65 418 420 10.2307/3280287 383936 (Pubitemid 10222999)
23. Genetic diversity and structure of African Plasmodium falciparum populations in urban and rural areas. Bogreau H, Renaud F, Bouchiba H, Durand P, Assi SB, Henry MC, Garnotel E, Pradines B, Fusai T, Wade B, Adehossi E, Parola P, Kamil MO, Puijalon O, Rogier C, Am J Trop Med Hyg 2006 74 953 959 16760503 (Pubitemid 351627399)
24. Urban malaria in Dakar, Senegal: chemosusceptibility and genetic diversity of Plasmodium falciparum isolates. Henry M, Diallo I, Bordes J, Ka S, Pradines B, Diatta B, M'Baye PS, Sane M, Thiam M, Gueye PM, Wade B, Touze JE, Debonne JM, Rogier C, Fusai T, Am J Trop Med Hyg 2006 75 146 151 16837722 (Pubitemid 351627584)
25. 2 for the evaluation of in vitro Plasmodium falciparum susceptibility to standard anti-malarial drugs. Pascual A, Basco LK, Baret E, Amalvict R, Travers D, Rogier C, Pradines B, Malar J 2011 10 8 10.1186/1475-2875-10-8 21235757
26. Online analysis of in vitro resistance to antimalarial drugs through nonlinear regression. Le Nagard H, Vincent C, Mentré F, Le Bras J, Comput Methods Programs Biomed 2010
27. World Antimalarial resistance Netwwork (WARN) II: In vitro antimalarial drug susceptibility. Bacon DJ, Jambou R, Fandeur T, Le Bras J, Wrongsrichanalai C, Fukuda MM, Ringwald P, Hopkins Sibley C, Kyle DE, Malar J 2007 6 120 10.1186/1475-2875-6-120 17822533 (Pubitemid 47561492)
28. Sensibilité in vitro de 85 isolats de Plasmodium falciparum au Sénégal. Pradines B, Rogier C, Fusai T, Tall A, Doury JC, Med Trop 1996 56 141 145 (Pubitemid 26264211)
29. In vitro activity of artemether against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial drugs. Pradines B, Rogier C, Fusai T, Tall A, Trape JF, Doury JC, Am J Trop Med Hyg 1998 58 354 357 9546418 (Pubitemid 28160760)
30. In vitro activity of pyronaridine and amodiaquine against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial agents. Pradines B, Tall A, Parzy D, Spiegel A, Fusai T, Hienne R, Trape JF, Doury JC, J Antimicrob Chemother 1998 42 333 339 10.1093/jac/42.3.333 9786473 (Pubitemid 28442447)
31. In vitro activities of benflumetol against 158 Senegalese isolates of Plasmodium falciparum in comparison with those of standard antimalarial drugs. Pradines B, Tall A, Fusai T, Spiegel A, Hienne R, Rogier C, Trape JF, Le Bras J, Parzy D, Antimicrob Agents Chemother 1999 43 418 420 9925550 (Pubitemid 29079190)
32. Antibiotics for prophylaxis of Plasmodium falciparum infections: in vitro activity of doxycycline against Senegalese isolates. Pradines B, Spiegel A, Rogier C, Tall A, Mosnier J, Fusai T, Trape JF, Parzy D, Am J Trop Med Hyg 2000 62 82 85 10761729 (Pubitemid 30180355)
33. In vitro activities of ferrochloroquine against 55 Senegalese isolates of Plasmodium falciparum in comparison with those of standard antimalarial drugs. Pradines B, Tall A, Rogier C, Spiegel A, Mosnier J, Marrama L, Fusai T, Millet P, Panconi E, Trape JF, Parzy D, Trop Med Int Health 2002 7 265 270 10.1046/j.1365-3156.2002.00848.x 11903989 (Pubitemid 34264379)
34. In vitro activity of iron-binding compounds against Senegalese isolates of Plasmodium falciparum. Pradines B, Tall A, Ramiandrasoa F, Spiegel A, Sokhna C, Fusai T, Mosnier J, Daries W, Trape JF, Kunesch G, Parzy D, Rogier C, J Antimicrob Chemother 2006 57 1093 1099 10.1093/jac/dkl117 16595639 (Pubitemid 44644410)
35. In vitro activity of tafenoquine against the asexual blood stages of Plasmodium falciparum isolates from Gabon, Senegal, and Djibouti. Pradines B, Mabika Mamfoumbi M, Tall A, Sokhna C, Koeck JL, Fusai T, Mosnier J, Czarnecki E, Spiegel A, Trape JF, Kombila M, Rogier C, Antimicrob Agents Chemother 2006 50 3225 3226 10.1128/AAC.00777-06 16940138 (Pubitemid 44396447)
36. Resistance of Plasmodium falciparum field isolates to in vitro artemether and point mutations of the SERCA-type PfATPase6. Jambou R, Legrand E, Niang M, Khim N, Lim P, Volney B, Ekala MT, Bouchier C, Esterre P, Fandeur T, Mercereau-Puijalon O, Lancet 2005 366 1960 1963 10.1016/S0140-6736(05)67787-2 16325698 (Pubitemid 41713986)
37. Sénégal et paludisme. Echec prophylactique vrai de la méfloquine. Gari-Toussaint M, Pradines B, Mondain V, Keundjian A, Dellamonica P, Le Fichoux Y, Presse Med 2002 31 1136 12162100 (Pubitemid 34760712)
38. Susceptibility of Plasmodium falciparum strains to mefloquine in an urban area in Senegal. Hatin I, Trape JF, Legros F, Bauchet J, Le Bras J, Bull World Health Organ 1992 70 363 367 1638665
39. Tests in vivo de chimiosensibilite de Plasmodium falciparum la chloroquine au Sénégal: évolution de la résistance et estimation de l'efficacité thérapeutique. Sokhna C, Molez JF, Ndiaye P, Sane B, Trape JF, Bull Soc Pathol Exot 1997 90 83 89 9289259
40. Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use. Norate N, Durand R, Tall A, Marrama L, Spiegel A, Sokhna C, Pradines B, Cojean S, Guillotte M, Bischoff E, Ekala MT, Bouchier C, Fandeur T, Ariey F, Patarapotikul J, Le Bras J, Trape JF, Rogier C, Mercereau-Puijalon O, PlosOne 2007 1 139
41. Evaluation de la sensibilité in vitro de Plasmodium falciparum la chloroquine par le Deli-test dans la région de Dakar (Séné gal). Dieng T, Bah IB, Ndiaye PM, Diallo I, Diop BM, Brasseur P, Mboup S, Wirth D, Ndir O, Med Trop 2005 65 580 583 (Pubitemid 44795540)
42. In vitro chloroquine susceptibility and PCR analysis of pfcrt and pfmdr1 polymorphisms in Plasmodium falciparum isolates from Senegal. Thomas SM, Ndir O, Dieng T, Mboup S, Wypij D, Maguire JH, Wirth DF, Am J Trop Med Hyg 2002 66 474 480 12201579
43. In vivo and in vitro analysis of chloroquine resistance in Plasmodium falciparum isolates from Senegal. Sarr O, Myrick A, Daily J, Diop BM, Dieng T, Ndir O, Salif Sow P, Mboup S, Wirth DF, Parasitol Res 2005 97 136 140 10.1007/s00436-005-1406-7 15986248 (Pubitemid 41225080)
44. Short report: an non-radioactive DAPI-based high-throughput in vitro assay to assess Plasmodium falciparum responsiveness to antimalarials-Increased sensitivity of P. falciparum to chloroquine in Senegal. Ndiaye D, Patel V, Demas A, LeRoux M, Ndir O, Mboup S, Clardy J, Lakshmanan V, Daily JP, Wirth DF, Am J Trop Med Hyg 2010 82 228 230 10.4269/ajtmh.2010.09-0470 20133997
45. Antimalarial drug use in general populations of tropical Africa. Gardella F, Assi S, Simon F, Bogreau H, Eggelte T, Ba F, Foumane V, Henry MC, Traore Kientega P, Basco L, Trape JF, Lalou R, Martelloni M, Desbordes M, Baragatti M, Briolant S, Almeras L, Pradines B, Fusai T, Rogier C, Malar J 2008 7 124 10.1186/1475-2875-7-124 18611279
46. Patterns of chloroquine use and resistance in sub-Saharan Africa: a systematic review of household survey and molecular data. Frosch AEP, Venkatesan M, Laufer MK, Malar J 2011 10 116 10.1186/1475-2875-10-116 21554692
47. Remergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine in Malawi. Kublin JG, Cortese JF, Njunju EM, Mukadam RA, Wirima JJ, Kazembe PN, Djimdé AA, Kouriba B, Taylor TE, Plowe CV, J Infect Dis 2003 187 1870 1875 10.1086/375419 12792863 (Pubitemid 36724485)
48. Return of chloroquine antimalarial efficacy in Malawi. Laufer MK, Thesing PC, Eddington ND, Masonga R, Dzinjalamala FK, Takala SL, Taylor TE, Plowe CV, N Engl J Med 2006 355 1959 1966 10.1056/NEJMoa062032 17093247 (Pubitemid 44708015)
49. Plasmodium falciparum in vitro susceptibility to antimalarial drugs in Casamance (Southwestern Senegal) during the first 5 years of routine use of artesunate-amodiaquine. Agnamey P, Brasseur P, Eldin de Pecoulas P, Vaillant M, Olliaro P, Antimicrob Agents Chemother 2006 50 1531 1534 10.1128/AAC.50.4.1531- 1534.2006 16569876
50. Amodiaquine remains effective for treating ucomplicated malaria in West and Central Africa. Brasseur P, Guiguemde R, Diallo S, Guiyedi V, Kombila M, Ringwald P, Olliaro P, Trans R Soc Trop Med Hyg 1999 93 645 650 10.1016/S0035-9203(99)90083-4 10717757 (Pubitemid 30015796)
51. Decreased sensitivity to chloroquine and quinine of some Plasmodium falciparum strains from Senegal in september 1984. Brandicourt O, Druilhe P, Diouf F, Brasseur P, Turk P, Danis M, Am J Trop Med Hyg 1986 35 717 721 3524287 (Pubitemid 16072232)
52. Quinine-resistant malaria in traveler returning from Senegal, 2007. Pradines B, Pistone T, Ezzedine K, Briolant S, Bertaux L, Receveur MC, Parzy D, Millet P, Rogier C, Malvy D, Emerg Infect Dis 2010 16 546 548 20202443
53. Multinormal in vitro distribution model suitable for the distribution of Plasmodium falciparum chemosusceptibility to doxycycline. Briolant S, Baragatti M, Parola P, Simon F, Tall A, Sokhna C, Hovette P, Mabika Mamfoumbi M, Koeck JL, Delmont J, Spiegel A, Castello J, Gardair JP, Trape JF, Kombila M, Minodier P, Fusai T, Rogier C, Pradines B, Antimicrob Agents Chemother 2009 53 688 695 10.1128/AAC.00546-08 19047651
54. In vitro activities of antibiotics against Plasmodium falciparum are inhibited by iron. Pradines B, Rogier C, Fusai T, Mosnier J, Daries W, Baret E, Parzy D, Antimicrob Agents Chemother 2001 45 1746 1750 10.1128/AAC.45.6.1746- 1750.2001 11353621 (Pubitemid 32466344)