Inlet ionization: A new highly sensitive approach for liquid chromatography/mass spectrometry of small and large molecules

Analytical Chemistry

Volumn 83, Issue 20, 2011, Pages 7591-7594

  Pagnotti, Vincent S ^a   Inutan, Ellen D ^b   Marshall, Darrell D ^b   McEwen, Charles N ^a   Trimpin, Sarah ^b  

^a University of the Sciences   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMINS; CHROMATOGRAPHIC PEAKS; CLOZAPINE; ELUENT FLOW RATE; FRAGMENT IONS; HIGH SENSITIVITY; HIGHLY SENSITIVE; IONIZATION MASS SPECTROMETRY; LC/MS/MS; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; MASS SPECTRA; NON-VOLATILE COMPOUNDS; REVERSE PHASE; SIGNAL TO NOISE; SOLVENT BASED; SOLVENT FLOW RATE; SOLVENT SYSTEM; TRYPTIC DIGESTS;

BODY FLUIDS; COLUMN CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; FLOW RATE; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; SIGNAL TO NOISE RATIO; SOLVENTS;

IONIZATION OF SOLIDS;

EID: 80054695482     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac201982r     Document Type: Article

References (24)

1. Mehlis, B.; Kertscher, U. Anal. Chim. Acta 1997, 352, 71
2. Korfmacher, W. A. Drug Discovery Today 2005, 10, 1357
3. Petrovic, M.; Hernando, D.; D'iax-Cruz, M.; Barcelo', D. J. Chromatogr., A 2005, 1067, 1
4. Wachs, T.; Conboy, J.; Henion, J. J. Chromatogr. Sci. 1991, 29, 357
5. Niessen, W.; Tinke, A. J. Chromatogr., A 1995, 703, 37
6. Sun, X.; Kelly, R. T.; Tang, K.; Smith, R. D. Anal. Chem. 2011, 83, 5797
7. Srinivas, P.; Krishna, P.; Sadanandam, M. Int. J. Ph. Sci. 2010, 2, 728
8. Vestal, M. L. J. Am. Soc. Mass Spectrom. 2011, 22, 953
9. Tang, K.; Page, J. S.; Marginean, I.; Kelly, R. T.; Smith, R. D. J. Am. Soc. Mass Spectrom. 2011, 22, 1318 - 1325.
10. Page, J. S.; Kelly, R. T.; Tang, K.; Smith, R. D. J. Am. Soc. Mass Spectrom. 2007, 18, 1582
11. Cech, N.; Enke, C. Mass Spectrom. Rev. 2001, 20, 362
12. Trimpin, S.; Herath, T. N.; Inutan, E. D.; Cernat, S. A.; Wager-Miller, J.; Mackie, K.; Walker, J. M. Rapid Commun. Mass Spectrom. 2009, 23, 3023
13. Trimpin, S.; Inutan, E. D.; Herath, T. N.; McEwen, C. N. Anal. Chem. 2010, 82, 11
14. Trimpin, S.; Inutan, E. D.; Herath, T. N.; McEwen, C. N. Mol. Cell. Proteomics 2010, 9, 362
15. McEwen, C. N.; Trimpin, S. Int. J. Mass Spectrom. 2011, 300, 167
16. Trimpin, S.; Ren, Y.; Wang, B.; Lietz, C. B.; Richards, A. L.; Marshall, A. G.; Inutan, E. D. Anal. Chem. 2011, 83, 5469
17. Inutan, E. D.; Wang, B.; Trimpin, S. Anal. Chem. 2011, 83, 678
18. Karas, M.; Hillenkamp, F. Anal. Chem. 1988, 60, 2299
19. McEwen, C. N.; Pagnotti, V. S.; Inutan, E. D.; Trimpin, S. Anal. Chem. 2010, 82, 9164
20. Pagnotti, V. S.; Chubatyi, N. D.; McEwen, C. N. Anal. Chem. 2011, 83, 3981
21. Vestal, M. L. Mass Spectrom. Rev. 1983, 2, 447
22. Fenn, J. B. J. Am. Soc. Mass Spectrom. 1993, 4, 524
23. Arpino, P. Mass Spectrom. Rev. 1990, 9, 631
24. Inutan, E. D.; Trimpin, S. J. Proteome Res. 2010, 9, 6077