Characterization of enhanced-fluidity liquid hydrophilic interaction chromatography for the separation of nucleosides and nucleotides

Journal of Chromatography A

Volumn 1218, Issue 45, 2011, Pages 8222-8230

  Philibert, Gwenaëlle S ^a   Olesik, Susan V ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Enthalpy; HILIC; Nucleotides; Peak tailing; Retention mechanism; Subcritical

Indexed keywords

1 ,4-DIAZABICYCLO[2.2.2]OCTANE; 1 ,5-DIAZABICYCLO[4.3.0]NON-5-ENE; ANALYTES; BIOLOGICAL MOLECULE; DISSOLVED GAS; DOMINANT MECHANISM; EXPERIMENTAL PARAMETERS; HILIC; HYDROPHILIC INTERACTION CHROMATOGRAPHY; ISOCRATIC CONDITIONS; ISOCRATIC SEPARATION; LIQUID CHROMATOGRAPHIC SEPARATIONS; MOBILE PHASE; MOBILE PHASIS; MOLE FRACTION; PEAK ASYMMETRY; PEAK TAILING; PHOSPHATE SALTS; RETENTION MECHANISM; SOLVENT STRENGTH; SUBCRITICAL; TRIETHYLAMINES;

CARBON DIOXIDE; FLUIDITY; GAS CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; NUCLEOTIDES; OPTIMIZATION; PHOSPHORYLATION; SODIUM CHLORIDE; THERMODYNAMICS;

LIQUIDS;

1,4 DIAZABICYCLO[2.2.2]OCTANE; ADENOSINE; ADENOSINE PHOSPHATE; CARBON DIOXIDE; CYTIDINE; CYTIDINE PHOSPHATE; GUANOSINE; GUANOSINE PHOSPHATE; METHANOL; NUCLEOSIDE; NUCLEOTIDE; PHOSPHATE; SODIUM CHLORIDE; SOLVENT; TRIETHYLAMINE; URIDINE; URIDINE PHOSPHATE; WATER;

ARTICLE; ENHANCED FLUIDITY LIQUID HYDROPHILIC INTERACTION CHROMATOGRAPHY; ENTROPY; GAS DIFFUSION; HYDROPHILIC INTERACTION CHROMATOGRAPHY; PRIORITY JOURNAL; SEPARATION TECHNIQUE; TEMPERATURE; THERMODYNAMICS; VISCOSITY;

ACETONITRILES; BICYCLO COMPOUNDS, HETEROCYCLIC; CARBON DIOXIDE; CHROMATOGRAPHY, LIQUID; ENTROPY; ETHYLAMINES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; METHANOL; MODELS, CHEMICAL; NUCLEOSIDES; NUCLEOTIDES; PHOSPHATES; PIPERAZINES; SODIUM CHLORIDE; TEMPERATURE; WATER;

EID: 80054690658     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.09.037     Document Type: Article

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