A delivery system to avoid self-aggregation and to improve in vitro and in vivo skin delivery of a phthalocyanine derivative used in the photodynamic therapy

Journal of Controlled Release

Volumn 155, Issue 3, 2011, Pages 400-408

  Rossetti, Fábia Cristina ^a   Lopes, Luciana Biagini ^b   Carollo, Aline Regina H ^a   Thomazini, José A ^a   Tedesco, Antônio Cláudio ^a   Bentley, Maria Vitória Lopes Badra ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

Microemulsion; Photodynamic therapy; Phthalocyanine; Skin cancer; Skin penetration enhancement

Indexed keywords

AGGREGATION PHENOMENA; BIODISTRIBUTIONS; CANOLA OIL; CONFOCAL LASER SCANNING MICROSCOPY; CONTROL SOLUTIONS; DELIVERY SYSTEMS; DIFFUSION CELLS; ELECTRICAL CONDUCTIVITY; IN-VITRO; IN-VIVO; INTERNAL PHASE; MONOMERIC FORMS; MONOMERIZATION; OIL-IN-WATER; PHOTODYNAMIC EFFICACY; PHTHALOCYANINE; PHTHALOCYANINE DERIVATIVES; PROPYLENE GLYCOLS; SELF AGGREGATION; SKIN CANCER; SKIN DELIVERY; SKIN PENETRATION; SKIN PENETRATION ENHANCEMENT; SPECTROSCOPIC TECHNIQUE; STRATUM CORNEUM; TERNARY PHASE DIAGRAMS; ZINC PHTHALOCYANINES;

CONFOCAL MICROSCOPY; ELECTRIC CONDUCTIVITY; GLYCOLS; LASER APPLICATIONS; MAMMALS; MICROEMULSIONS; NITROGEN COMPOUNDS; PHASE DIAGRAMS; PHOTOSENSITIZERS; PLASMONS; PROPYLENE; SURFACE ACTIVE AGENTS; VISUALIZATION; ZETA POTENTIAL; ZINC COMPOUNDS;

PHOTODYNAMIC THERAPY;

MONOMER; PHTHALOCYANINE DERIVATIVE; PHTHALOCYANINE ZINC; PROPYLENE GLYCOL; SURFACTANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DERMIS; DIFFUSION CHAMBER; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG FORMULATION; ELECTRIC CONDUCTIVITY; EPIDERMIS; FEMALE; FLUOROMETRY; HAIRLESS MOUSE; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MICROEMULSION; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOMETRY; PRIORITY JOURNAL; RAPESEED; SKIN PENETRATION; SPECTROSCOPY; STRATUM CORNEUM; ZETA POTENTIAL;

ANIMALS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; ELECTRIC CONDUCTIVITY; EMULSIONS; FEMALE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INDOLES; LIGHT; MICE; MICE, HAIRLESS; MICROSCOPY, CONFOCAL; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; SCATTERING, RADIATION; SKIN; SKIN ABSORPTION; SWINE; TISSUE DISTRIBUTION; VISCOSITY;

EID: 80054686262     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.06.034     Document Type: Article

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