N-Nicotinoyl dopamine, a novel niacinamide derivative, retains high antioxidant activity and inhibits skin pigmentation

Experimental Dermatology

Volumn 20, Issue 11, 2011, Pages 950-952

  Kim, Bora ^a   Kim, Jin Eun ^a   Lee, Su Min ^a   Lee, Soung Hoon ^b   Lee, Jin Won ^a   Kim, Myung Kyoo ^c   Lee, Kye Jong ^a   Kim, Hyuk ^a   Lee, Joo Dong ^a   Choi, Kang Yell ^b  

^a Enprani Co Ltd   (South Korea)

^b Yonsei University   (South Korea)

^c Samkyung Costech Co Ltd   (South Korea)

Author keywords

Antioxidant effect; Niacinamide N nicotinoyl dopamine; Skin pigmentation

Indexed keywords

ANTIOXIDANT; DEPIGMENTING AGENT; DOPAMINE; MELANIN; MONOPHENOL MONOOXYGENASE; N NICOTINOYL DOPAMINE; NICOTINAMIDE DERIVATIVE; NICOTINIC ACID; PLACEBO; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; CELL VIABILITY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG SYNTHESIS; EMULSION; ENZYME INHIBITION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LETTER; MELANOCYTE; MELANOGENESIS; MELANOMA CELL; MOUSE; NONHUMAN; NORMAL HUMAN; OXIDATIVE STRESS; SIDE EFFECT; SKIN IRRITATION; SKIN PIGMENTATION; SKIN SENSITIZATION;

ANIMALS; ANTIOXIDANTS; BLEACHING AGENTS; CELL LINE; CELL LINE, TUMOR; DOPAMINE; HUMANS; HYPERPIGMENTATION; MELANOMA, EXPERIMENTAL; MICE; NIACINAMIDE; SKIN PIGMENTATION;

EID: 80054106568     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2011.01345.x     Document Type: Letter

References (16)

1. Solano F, Briganti S, Picardo M et al. Pigment Cell Res 2006: 19: 550-571.
2. Briganti S, Camera E, Picardo M. Pigment Cell Res 2003: 16: 101-110.
3. Minwalla L, Zhao Y, Le Poole I C et al. J Invest Dermatol 2001: 117: 341-347.
4. Greatens A, Hakozaki T, Koshoffer A et al. Exp Dermatol 2005: 14: 498-508.
5. Ma H J, Zhao G, Zi S X et al. Exp Dermatol 2010: 19: e282-e285.
6. Matsuda H, Morikawa T, Toguchida I et al. Bioorg Med Chem 2001: 9: 41-50.
7. Shelanski M V, Phillips S B, Potts C E. Int J Dermatol 1996: 35: 137-140.
8. Kristiansen K A, Jensen P E, Moller I M et al. Physiol Plant 2009: 136: 369-383.
9. Duval C, Smit N P M, Kolb A M et al. Pigment Cell Res 2002: 15: 440-446.
10. Park H Y, Kosmadaki M, Yaar M et al. Cell Mol Life Sci 2009: 66: 1493-1506.
11. Singh S K, Nizard C, Kurfurst R et al. Exp Dermatol 2008: 17: 418-426.
12. Scott G, Leopardi S, Printup S et al. J Invest Dermatol 2004: 122: 1214-1224.
13. Tang A, Eller M, Hara M et al. J Cell Sci 1994: 107: 983-992.
14. Ito Y, Kanamaru A, Tada A. Biochim Biophys Acta 2006: 1760: 487-494.
15. Birk Y, Khalef S, Jibson M D. Arch Biochem Biophys 1983: 225: 451-457.
16. Berson D J. Drugs Dermatol 2008: 7: s7-s12.