Porous poly(D, L -lactic acid) foams with tunable structure and mechanical anisotropy prepared by supercritical carbon dioxide

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 99 B, Issue 2, 2011, Pages 338-349

  Floren, Michael ^a,b   Spilimbergo, Sara ^a   Motta, Antonella ^a,b   Migliaresi, Claudio ^a,b  

^a UNIVERSITY OF TRENTO   (Italy)

^b European Institute of Excellence on Tissue Engineering and Regenerative Medicine   (Italy)

Author keywords

mechanical properties; morphology; scaffolds; tissue engineering

Indexed keywords

BONE TISSUE ENGINEERING; COMPRESSIVE MODULI; DEGREES OF ANISOTROPY; ENGINEERED TISSUES; FOAMING DIRECTION; GAS FOAMING; GAS FOAMING CONDITION; MECHANICAL ANISOTROPY; MECHANICAL BEHAVIOR; MECHANICAL EVALUATION; POLY(D , L-LACTIC ACID); POLYMERIC FOAMS; PORE GEOMETRY; POROUS SCAFFOLD; PROCESSING CONDITION; SCAFFOLD MORPHOLOGY; SUPERCRITICAL CARBON DIOXIDES; TISSUE SCAFFOLDS; TUNABILITIES;

ANISOTROPY; BIOMECHANICS; BLOWING AGENTS; BODY FLUIDS; CARBON DIOXIDE; FOAMS; LACTIC ACID; MORPHOLOGY; SCAFFOLDS (BIOLOGY); SUPERCRITICAL FLUID EXTRACTION; TISSUE;

MECHANICAL PROPERTIES;

CARBON DIOXIDE; POLYGLACTIN; POROUS POLYMER; TISSUE SCAFFOLD;

ANISOTROPY; ARTICLE; GEOMETRY; MORPHOLOGY; PERFORMANCE; TEMPERATURE; TISSUE ENGINEERING;

ANISOTROPY; BONE AND BONES; CALORIMETRY, DIFFERENTIAL SCANNING; CARBON DIOXIDE; LACTIC ACID; POLYMERS; POROSITY; POWDERS; PRESSURE; STRESS, MECHANICAL; SURFACE PROPERTIES; TEMPERATURE; TIME FACTORS; TISSUE ENGINEERING;

EID: 80054106386     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31905     Document Type: Article

References (39)

1. Langer R, Vacanti JP,. Tissue Engineering. Science 1993; 260: 920-926. (Pubitemid 23209960)
2. Mahmood TA, Groot KD, Blitterswijk CA, Barre F,. Advanced biomaterials for skeletal tissue regeneration: Instructive and smart functions. Mater Sci Eng R 2008; 59: 38-71. (Pubitemid 351625615)
3. Chua C,. Review: The design of scaffolds for use in tissue engineering. Part I. Traditional Factors. Tissue Eng 2001; 7: 679-689. (Pubitemid 34042301)
4. Mikos AG, Thorsen AJ, Czerwonka LA, Bao Y, Langer R, Winslow DN, Vacanti JP,. Preparation and characterization of poly (L-lactic acid) foams. Polymer 1993; 35: 1068-1077.
5. Lo H, Ponticiello MS, Leong KW,. Fabrication of controlled release biodegradable foams by phase separation. Tissue Eng 1995; 1: 15-28.
6. Hutmacher DW, Sittinger M, Risbud MV,. Scaffold-based tissue engineering: Rationale for computer-aided design and solid free-form fabrication systems. Trends Biotechnol 2004; 22: 354-362. (Pubitemid 38887544)
7. Mooney DJ, Baldwin DF, Suht NP, Vacanti JP, Langer R,. Novel approach to fabricate porous sponges of poly(D, L-lactic-co-glycolic acid) without the use of organic solvents. Biomaterials 1996; 17: 1417-1422. (Pubitemid 26237549)
8. Shieh Y, Su J, Manivannan G, Lee PHC, Sawan SP, Spall DW,. Interaction of supercritical carbon dioxide with polymers. II. Amorphous polymers. J Appl Polym Sci 1996; 59: 707-717. (Pubitemid 126588144)
9. Jacobs LJM, Kemmere MF, Keurentjes JTF,. Sustainable polymer foaming using high pressure carbon dioxide: A review on fundamentals, processes and applications. Green Chem 2008; 10: 731-738. (Pubitemid 351905032)
10. 2. Biotechnol Bioeng 2003; 84: 627-638. (Pubitemid 37420334)
11. Kazarian SG,. Polymer Processing with Supercritical Fluids. Polym Sci C 2000; 42: 78-101.
12. Goel SK, Beckman EJ,. Generation of microcellular polymeric foams using supercritical carbon dioxide. I: Effect of pressure and temperature on nucleation. Polym Eng Sci 1994; 34: 1137-1147.
13. Tai H, Mather ML, Howard D, Wang W, White LJ, Crowe JA, Morgan SP, Chandra A, Williams DJ, Howdel SM, Shakesheff KM,. Control of pore size and structure of tissue engineering scaffolds produced by supercritical fluid processing. Eur Cell Mater 2007; 14: 64-77.
14. Howdle SM, Watson MS, Whitaker MJ, Popav VK, Davis MD, Mandel FS, Wang JD, Shakesheff KM,. Supercritical fluid mixing: Preparation of thermally sensitive polymer composites containing bioactive materials. Chem Commun 2001; 1: 109-110. (Pubitemid 32094839)
15. Baker KC, Bellair R, Manitiu M, Herkowitz HN, Kannan RM,. Structure and mechanical properties of supercritical carbon dioxide processed porous resorbable polymer constructs. J Mech Behav Biomed Mater 2009; 2: 620-626.
16. Jenkins MJ, Harrison KL, Silva M, Whitaker MJ, Shakesheff KM, Howdle SM,. Characterization of microcellular foams produced from semi-crystalline PCL using supercritical carbon dioxide. Eur Polym J 2006; 42: 3145-3151. (Pubitemid 44572295)
17. Tsivintzelis I, Pavlidou E, Panayiotou C,. Biodegradable polymer foams prepared with supercritical CO2-ethanol mixtures as blowing agents. J Supercrit Fluids 2007; 42: 265-272. (Pubitemid 46898740)
18. Barry JJ, Gidda HS, Scotchford CA, Howdle SM,. Porous methacrylate scaffolds: Supercritical fluid fabrication and in vitro chondrocyte responses. Biomaterials 2004; 25: 3559-3568. (Pubitemid 38327045)
19. Oliveira NS, Gonc CM, Coutinho JA, Ferreira A,. Carbon dioxide, ethylene and water vapor sorption in poly(lactic acid). Fluid Phase Equilib 2006; 250: 116-124. (Pubitemid 44834452)
20. Gualandi C, White LJ, Chen L, Gross RA, Shakesheff KM, Howdle SM, Scandola M,. Scaffold for tissue engineering fabricated by non-isothermal supercritical carbon dioxide foaming of a highly crystalline polyester. Acta Biomater 2010; 6: 130-136.
21. Mathieu LM, Montjovent MO, Bourban P, Pioletti DP, MÃ¥nson JAE,. Bioresorbable composites prepared by supercritical fluid foaming. J Biomed Mater Res A 2005; 75: 89-97. (Pubitemid 41298190)
22. Huber AT, Gibson LJ,. Anisotropy of Foams. J Mater Sci 1988; 23: 3031-3040.
23. Arora KA, Lesser AJ, McCarthy TJ,. Compressive behavior of microcellular polystyrene foams processed in supercritical carbon dioxide. Polym Eng Sci 1998; 38: 2055-2062. (Pubitemid 128597813)
24. Mathieu LM, Mueller TL, Bourban P, Pioletti DP, Müller R, MÃ¥nson JAE,. Architecture and properties of anisotropic polymer composite scaffolds for bone tissue engineering. Biomaterials 2006; 27: 905-916. (Pubitemid 41484123)
25. Maquet V, Blacher S, Pirarad R, Pirarad JP, Vyakarnam MN, Jérôme R,. Preparation of macroporous biodegradable poly(L-lactide-co-Ã¥-caprolactone) foams and characterization by mercury intrusion porosimetry, image analysis, and impedance spectroscopy. J Biomed Mater Res A 2002; 66A: 199-213. (Pubitemid 37517219)
26. Rasband WS,. ImageJ, U. S. National Institutes of Health. Bethesda, Maryland, USA, 1997-2005
27. Simone AE, Gibson LJ,. Aluminum foams produced by liquid-state processes. Acta Mater 1998; 46: 3109-3123. (Pubitemid 128422784)
28. Harris LD, Kim BS, Mooney DJ,. Open pore biodegradable matrices formed with gas foaming. J Biomed Mater Res 1998; 42: 396-402. (Pubitemid 28452514)
29. ASTM Standard D1621-10, 2010, "Standard Test Method for Compressive Properties of Rigid Cellular Plastics," ASTM International, West Conshohocken, PA, 2010.
30. Kumar V,. Microcellular polymers: Novel materials for the 21st century. Prog Rub Plast Tech 1993; 9: 54-70.
31. Gibson LJ, Ashby MF,. The mechanics of three-dimensional cellular materials. Proc R Soc Lond 1982; A382: 43-59.
32. Pini R, Storti G, Mazzotti M, Tai H, Shakesheff KM, Howdle SM,. Sorption and Swelling of Poly(D, L-lactic acid) and Poly(lactic-co-glycolic acid) in Supercritical CO2. Macromol Symp 2007; 259: 197-202. (Pubitemid 351189952)
33. Gibson LJ, Ashby MF,. Cellular solids: Structure and properties. Oxford: Pergamon Press; 1988.
34. Silva MJ, Gibson LJ,. The effects of non-periodic microstructure and defects on the compressive strength of two-dimensional cellular solids. Int J Mech Sci 1997; 39: 549-563. (Pubitemid 127426965)
35. Vajjhala S, Kraynik AM, Gibson LJ,. A cellular solid model for modulus reduction due to resorption of traveculae in bone. J Biomech Eng 2000; 122: 511-515.
36. Silva MJ, Hayes WC, Gibson LJ,. The effects of non-periodic microstructure on the elastic properties of two-dimensional cellular solids. Int J Mech Sci 1995; 37: 1161-1177.
37. Li K, Gao XL, Subhash G,. Effects of cell shape and cell wall thickness variations on the elastic properties of two-dimensional cellular solids. Int J Sol Struct 2005; 42: 1777-1795.
38. Grenestedt JT, Bassinet F,. Influence of cell wall thickness variations on the stiffness of closed-cell cellular solids. Int J Mech Sci 2000; 42: 1327-1338. (Pubitemid 30595000)
39. Simone AE, Gibson LJ,. Effects of solid distribution on the stiffness and strength of metallic foams. Acta Mater 1998; 46: 2139-2150. (Pubitemid 128438483)