Preparation of nucleosides derived from 2-nitroimidazole and d -arabinose, d -ribose, and d -Galactose by the Vorbrüggen method and their conversion to potential precursors for tracers to image hypoxia

Journal of Organic Chemistry

Volumn 76, Issue 20, 2011, Pages 8159-8167

  Schweifer, Anna ^a   Hammerschmidt, Friedrich ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ANOMERICS; ANOMERS; COUPLING PROCEDURE; D-ARABINOSE; D-GALACTOSE; D-RIBOSE; HYDROXYL GROUPS; MILD TEMPERATURES; NUCLEOSIDE ANALOGUES; ONE-POT REACTION; TRIFLATES;

ACETONITRILE; CHLORINE COMPOUNDS;

BIOMOLECULES;

1 ALPHA (2',3' DI O ACETYL DEXTRO ARABINOFURANOSYL) 2 NITROIMIDAZOLE; 1 ALPHA (2',3',5 TRI O BENZOYL DEXTRO RIBOFURANOSYL) 2 NITROIMIDAZOLE; 1 ALPHA [1,2 DI O ACETYL 3,5 O,O (1,1,3,3 TETRAISOPROPYLDISILOXANYLIDENE) DEXTRO RIBOFURANOSE; 1 ALPHA [2' O ACETYL 3',5' O,O (1,1,3,3 TETRAISOPROPYLDISILOXANYLIDENE) DEXTRO RIBOFURANOSYL] 2 NITROIMIDAZOLE; 1 ALPHA [2',3' DI O ACETYL 5' O (4 TOLUENESULFONYL) DEXTRO ARABINOFURANOSYL] 2 NITROIMIDAZOLE; 1 ALPHA [2',3' DI O ACETYL 5' O (TERT BUTYLDIPHENYLSILYL) DEXTRO ARABINOFURANOSYL] 2 NITROIMIDAZOLE; 1 BETA (2',3',5 TRI O BENZOYL DEXTRO RIBOFURANOSYL) 2 NITROIMIDAZOLE; 1 BETA [1,2 DI O ACETYL 3,5 O,O (1,1,3,3 TETRAISOPROPYLDISILOXANYLIDENE) DEXTRO RIBOFURANOSE; 1 BETA [2' O ACETYL 3',5' O,O (1,1,3,3 TETRAISOPROPYLDISILOXANYLIDENE) DEXTRO RIBOFURANOSYL] 2 NITROIMIDAZOLE; 1 BETA [2',3' DI O ACETYL 5' O (TERT BUTYLDIPHENYLSILYL) DEXTRO RIBOFURANOSYL] 2 NITROIMIDAZOLE; 1 BETA [2',3',4',6' TETRA O ACETYL DEXTRA GALACTOPYRANOSYL) 2 NITROIMIDAZOLE; 1,2,3 TRI O ACETYL 5 O (TERT BUTYLDIPHENYLSILYL) ALPHA DEXTRO ARABINOFURANOSE; 1,2,3 TRI O ACETYL 5 O (TERT BUTYLDIPHENYLSILYL) ALPHA DEXTRO RIBOFURANOSE; 1,2,3 TRI O ACETYL 5 O (TERT BUTYLDIPHENYLSILYL) BETA DEXTRO ARABINOFURANOSE; 1,2,3 TRI O ACETYL 5 O (TERT BUTYLDIPHENYLSILYL) BETA DEXTRO RIBOFURANOSE; 2 NITROIMIDAZOLE; 2 NITROIMIDAZOLE DERIVATIVE; ACETIC ACID DERIVATIVE; ACETONITRILE; ARABINOSE; GALACTOSE; HYDROXYL GROUP; HYPOXIA IMAGING AGENT; NUCLEOSIDE DERIVATIVE; PYRIDINE; RIBOSE; SILANE DERIVATIVE; TERT BUTYLDIPHENYLSILYL CHLORIDE; TRACER; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACETYLATION; ARTICLE; HYPOXIA; LOW TEMPERATURE; MOLECULAR IMAGING; ONE POT SYNTHESIS; REACTION ANALYSIS; SILYLATION; TUMOR HYPOXIA;

ACETONITRILES; ANIMALS; ANOXIA; ARABINOSE; GALACTOSE; HUMANS; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR IMAGING; NEOPLASMS; NITROIMIDAZOLES; NUCLEOSIDES; RADIOACTIVE TRACERS; RIBOSE; SILANES;

EID: 80054099357     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo200727k     Document Type: Article

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