Absorption and transportation characteristic of six linear furocoumarins in a model of Caco-2 cell monolayer in human intestine

Chinese Traditional and Herbal Drugs

Volumn 42, Issue 1, 2011, Pages 96-102

  Li, Su Ning ^a,b   Yang, Xiu Wei ^a,b  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Caco 2 cell; Coumarin; Imperatorin; Intestinal absorption; Isoimperatorin; Xanthotoxin; Xanthotoxol

Indexed keywords

ATENOLOL; BERGAPTEN; CNIDILIN; FUROCOUMARIN; GLUCOPYRANOSIDE; ISOIMPERATORIN; ISOPIMPINELLIN; METHOXSALEN; OSTHOLE; PENTOSALEN; PROPRANOLOL; PSORALEN; UMBELLIFERONE; UNCLASSIFIED DRUG; XANTHOTOXOL;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; DRUG STRUCTURE; DRUG TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; LIPOPHILICITY; MONOLAYER CULTURE; ULTRAVIOLET RADIATION;

EID: 80054094466     PISSN: 02532670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Yang X W, Guo Q M, Wang Y, et al. Intestinal permeability of antivirus constituents from the fruits of Eucalyptus globulus Labill. in Caco-2 cell model [J]. Bioorg Med Chem Lett, 2007, 17(4): 1107-1111. (Pubitemid 46177600)
2. Zheng Y, Yang X W. Absorption and transport of pachymic acid in the human intestinal cell line Caco-2 monolayers [J]. J Chin Integr Med, 2008, 6(7): 704-710.
3. Tian X J, Yang X W, Yang X D, et al. Studies of intestinal permeability of 36 flavonoids using Caco-2 cell monolayer model [J]. Int J Pharm, 2009, 367(1): 58-64.
4. Wang Y, Yang X W. Intestinal transport of free anthraquinones in Caco-2 cell model [J]. Chin J Nat Med, 2008, 6(3): 141-145. (Pubitemid 351454317)
5. Yang X W, Teng J, Xu W, et al. The permeability and the efflux of alkaloids of the Evodiae Fructus in the Caco-2 model [J]. Phytother Res, 2009, 23(1): 56-60.
6. Ma L, Yang X W, Xu W, et al. Intestinal permeability of antitumor alkaloids from the processed seeds of Strychnos nux-vomica in a Caco-2 cell model [J]. Planta Med, 2009, 75(6): 631-634.
7. Yang X W, Teng J, Zhao B, et al. Studies on absorption and transport of limoninoids from Fructus Evodiae in Caco-2 cell monolayer model [J]. Chin Herb Med, 2009, 1(1): 53-58.
8. Yang X W, Hattori M, Namba T. Two new coumarins from the roots of Aegle marmelos [J]. J Chin Pharm Sci, 1996, 5(2): 68-73.
9. Artursson S, Palm K, Luthman K. Caco-2 monolayers in experimental and theoretical predictions of drug transport [J]. Adv Drug Deliv Rev, 2001, 46(123): 27-43.
10. van de Waterbeemd H, Camenisch G, Folkers G, et al. Estimation of Caco-2 cell permeability using calculated molecular descriptors [J]. Quant Struct-Act Relat, 1996, 15: 480-490. (Pubitemid 27023202)