-
1
-
-
0037160968
-
Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint reduction in hypertension study (LIFE); A randomised trial against atenolol
-
Dahlö f B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, de Faire U, et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE); a randomised trial against atenolol. Lancet 2002; 359:995-1003.
-
(2002)
Lancet
, vol.359
, pp. 995-1003
-
-
Dahlöf, B.D.1
-
2
-
-
34247379373
-
Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): A randomised, open-label, blinded endpoint morbidity-mortality study
-
DOI 10.1016/S0140-6736(07)60669-2, PII S0140673607606692
-
Mochizuki S, Dahlö f B, Shimizu M, Ikewaki K, Yoshikawa M, Taniguchi I, et al. Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study. Lancet 2007; 369:1431-1439. (Pubitemid 46635780)
-
(2007)
Lancet
, vol.369
, Issue.9571
, pp. 1431-1439
-
-
Mochizuki, S.1
Dahlof, B.2
Shimizu, M.3
Ikewaki, K.4
Yoshikawa, M.5
Taniguchi, I.6
Ohta, M.7
Yamada, T.8
Ogawa, K.9
Kanae, K.10
Kawai, M.11
Seki, S.12
Okazaki, F.13
Taniguchi, M.14
Yoshida, S.15
Tajima, N.16
-
3
-
-
0038053724
-
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin i to angiotensin 1-9
-
Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000; 87:E1-E9.
-
(2000)
Circ Res
, vol.87
-
-
Donoghue, M.1
Hsieh, F.2
Baronas, E.3
Godbout, K.4
Gosselin, M.5
Stagliano, N.6
-
4
-
-
0034721906
-
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
-
Tipnis SR, Hooper NM, Hyde R, Karran E, Christie G, Turner AJ. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 2000; 275:33238-33243.
-
(2000)
J Biol Chem
, vol.275
, pp. 33238-33243
-
-
Tipnis, S.R.1
Hooper, N.M.2
Hyde, R.3
Karran, E.4
Christie, G.5
Turner, A.J.6
-
5
-
-
18544378161
-
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
-
DOI 10.1074/jbc.M200581200
-
Vickers C, Hales P, Kaushik V, Dick L, Gavin J, Tang J, et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 2002; 277:14838-14843. (Pubitemid 34952556)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.17
, pp. 14838-14843
-
-
Vickers, C.1
Hales, P.2
Kaushik, V.3
Dick, L.4
Gavin, J.5
Tang, J.6
Godbout, K.7
Parsons, T.8
Baronas, E.9
Hsieh, F.10
Acton, S.11
Patane, M.12
Nichols, A.13
Tummino, P.14
-
6
-
-
33749437743
-
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR
-
DOI 10.1152/physiolgenomics.00312.2005
-
Diez-Freire C, Vázquez J, Correa de Adjounian MF, Ferrari MF, Yuan L, Silver X, et al. ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR. Physiol Genomics 2006; 27: 12-19. (Pubitemid 44511821)
-
(2006)
Physiological Genomics
, vol.27
, Issue.1
, pp. 12-19
-
-
Diez-Freire, C.1
Vazquez, J.2
Correa De Adjounian, M.F.3
Ferrari, M.F.R.4
Yuan, L.5
Silver, X.6
Torres, R.7
Raizada, M.K.8
-
7
-
-
0037142101
-
Angiotensin-converting enzyme 2 is an essential regulator of heart function
-
DOI 10.1038/nature00786
-
Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 2002; 417:822-828. (Pubitemid 34670323)
-
(2002)
Nature
, vol.417
, Issue.6891
, pp. 822-828
-
-
Crackower, M.A.1
Sarao, R.2
Oudit, G.Y.3
Yagil, C.4
Kozieradzki, I.5
Scanga, S.E.6
Oliveira-Dos-Santos, A.J.7
Da Costa, J.8
Zhang, L.9
Pei, Y.10
Scholey, J.11
Ferrarlo, C.M.12
Manoukian, A.S.13
Chappell, M.C.14
Backx, P.H.15
Yagil, Y.16
Penninger, J.M.17
-
8
-
-
67650541842
-
Devil and angel in the renin-angiotensin system: ACEangiotensin II-AT1 receptor axis vs ACE2-angiotensin-(1-7)-mas receptor axis
-
Iwai M, Horiuchi M. Devil and angel in the renin-angiotensin system: ACEangiotensin II-AT1 receptor axis vs. ACE2-angiotensin-(1-7)-mas receptor axis. Hypertens Res 2009; 32:533-536.
-
(2009)
Hypertens Res
, vol.32
, pp. 533-536
-
-
Iwai, M.1
Horiuchi, M.2
-
9
-
-
33846256550
-
ACE2 of the heart: From angiotensin I to angiotensin (1-7)
-
DOI 10.1016/j.cardiores.2006.09.006, PII S0008636306004056
-
Keidar S, Kaplan M, Gamliel-Lazarovich A. ACE2 of the heart: from angiotensin I to angiotensin (1-7). Cardiovasc Res 2007; 73:463-469. (Pubitemid 46091776)
-
(2007)
Cardiovascular Research
, vol.73
, Issue.3
, pp. 463-469
-
-
Keidar, S.1
Kaplan, M.2
Gamliel-Lazarovich, A.3
-
10
-
-
52049095952
-
Molecular mechanisms involved in the angiotensin-(1-7)/Mas signaling pathway in cardiomyocytes
-
Dias-Peixoto MF, Santos RA, Gomes ER, Alves MN, Almeida PW, Greco L, et al. Molecular mechanisms involved in the angiotensin-(1-7)/Mas signaling pathway in cardiomyocytes. Hypertension 2008; 52:542-548.
-
(2008)
Hypertension
, vol.52
, pp. 542-548
-
-
Dias-Peixoto, M.F.1
Santos, R.A.2
Gomes, E.R.3
Alves, M.N.4
Almeida, P.W.5
Greco, L.6
-
11
-
-
73849095442
-
Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3', 5'-cyclic monophosphate-dependent pathway
-
Gomes ER, Lara AA, Almeida PW, Guimaraes D, Resende RR, Campagnole-Santos MJ, et al. Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3', 5'-cyclic monophosphate-dependent pathway. Hypertension 2010; 55:153-160.
-
(2010)
Hypertension
, vol.55
, pp. 153-160
-
-
Gomes, E.R.1
Lara, A.A.2
Almeida, P.W.3
Guimaraes, D.4
Resende, R.R.5
Campagnole-Santos, M.J.6
-
12
-
-
19644384705
-
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2
-
DOI 10.1161/CIRCULATIONAHA.104.510461
-
Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA, et al. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 2005; 111:2605-2610. (Pubitemid 40740859)
-
(2005)
Circulation
, vol.111
, Issue.20
, pp. 2605-2610
-
-
Ferrario, C.M.1
Jessup, J.2
Chappell, M.C.3
Averill, D.B.4
Brosnihan, K.B.5
Tallant, E.A.6
Diz, D.I.7
Gallagher, P.E.8
-
13
-
-
33846043074
-
Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme
-
DOI 10.1291/hypres.29.865
-
Agata J, Ura N, Yoshida H, Shinshi Y, Sasaki H, Hyakkoku M, et al. Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme. Hypertens Res 2006; 29:865-874. (Pubitemid 46062117)
-
(2006)
Hypertension Research
, vol.29
, Issue.11
, pp. 865-874
-
-
Agata, J.1
Ura, N.2
Yoshida, H.3
Shinshi, Y.4
Sasaki, H.5
Hyakkoku, M.6
Taniguchi, S.7
Shimamoto, K.8
-
14
-
-
0027190950
-
Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes
-
Fukamizu A, Sugimura K, Takimoto E, Sugiyama F, Seo MS, Takahashi S, et al. Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. J Biol Chem 1993; 268:11617-11621. (Pubitemid 23168109)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.16
, pp. 11617-11621
-
-
Fukamizu, A.1
Sugimura, K.2
Takimoto, E.3
Sugiyama, F.4
Seo, M.-S.5
Takahashi, S.6
Hatae, T.7
Kajiwara, N.8
Yagami, K.-I.9
Murakami, K.10
-
15
-
-
60549113487
-
Exaggeration of focal cerebral ischemia in transgenic mice carrying human renin and human angiotensinogen genes
-
Inaba S, IwaiM, Tomono Y, Senba I, Furuno M, Kanno H, et al. Exaggeration of focal cerebral ischemia in transgenic mice carrying human renin and human angiotensinogen genes. Stroke 2009; 40:597-603.
-
(2009)
Stroke
, vol.40
, pp. 597-603
-
-
Inaba, S.1
Iwaim Tomono, Y.2
Senba, I.3
Furuno, M.4
Kanno, H.5
-
16
-
-
0036141914
-
Effect of angiotensin II type 1 receptor blockade on cardiac remodeling in angiotensin II type 2 receptor null mice
-
DOI 10.1161/hq0102.102277
-
Wu L, Iwai M, Nakagami H, Chen R, Suzuki J, Akishita M, et al. Effect of angiotensin II type 1 receptor blockade on cardiac remodeling in angiotensin II type 2 receptor null mice. Arterioscler Thromb Vasc Biol 2002; 22:49-54. (Pubitemid 34076231)
-
(2002)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.22
, Issue.1
, pp. 49-54
-
-
Wu, L.1
Iwai, M.2
Nakagami, H.3
Chen, R.4
Suzuki, J.5
Akishita, M.6
De Gasparo, M.7
Horiuchi, M.8
-
17
-
-
0036141820
-
Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury
-
Szö cs K, Lassègue B, Sorescu D, Hilenski LL, Valppu L, Couse TL, et al. Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury. Arterioscler Thromb Vasc Biol 2002; 22:21-27.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 21-27
-
-
Szö Cs, K.L.1
-
18
-
-
59849091253
-
Continuous activation of renin-angiotensin system impairs cognitive function in renin/angiotensinogen transgenic mice
-
Inaba S, Iwai M, Furuno M, Tomono Y, Kanno H, Senba I, et al. Continuous activation of renin-angiotensin system impairs cognitive function in renin/angiotensinogen transgenic mice. Hypertension 2009; 53:356-362.
-
(2009)
Hypertension
, vol.53
, pp. 356-362
-
-
Inaba, S.1
Iwai, M.2
Furuno, M.3
Tomono, Y.4
Kanno, H.5
Senba, I.6
-
19
-
-
58549083347
-
Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists
-
Inaba S, Iwai M, Tomono Y, Senba I, Furuno M, Kanno H, et al. Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists. Am J Hypertens 2009; 22:145-150.
-
(2009)
Am J Hypertens
, vol.22
, pp. 145-150
-
-
Inaba, S.1
Iwai, M.2
Tomono, Y.3
Senba, I.4
Furuno, M.5
Kanno, H.6
-
20
-
-
0033956274
-
The potential role of nitric oxide in the hypertrophic growth of the left ventricle
-
Simko F, Simko J. The potential role of nitric oxide in the hypertrophic growth of the left ventricle. Physiol Res 2000; 49:37-46. (Pubitemid 30111295)
-
(2000)
Physiological Research
, vol.49
, Issue.1
, pp. 37-46
-
-
Simko, F.1
Simko, J.2
-
21
-
-
0037167714
-
Long-term treatment with N(omega)-nitro-L-arginine methyl ester causes arteriosclerotic coronary lesions in endothelial nitric oxide synthasedeficient mice
-
Suda O, Tsutsui M, Morishita T, Tanimoto A, Horiuchi M, Tasaki H, et al. Long-term treatment with N(omega)-nitro-L-arginine methyl ester causes arteriosclerotic coronary lesions in endothelial nitric oxide synthasedeficient mice. Circulation 2002; 106:1729-1735.
-
(2002)
Circulation
, vol.106
, pp. 1729-1735
-
-
Suda, O.1
Tsutsui, M.2
Morishita, T.3
Tanimoto, A.4
Horiuchi, M.5
Tasaki, H.6
-
22
-
-
30744445980
-
Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men: Results of the MONICA Augsburg echocardiographic substudy
-
DOI 10.1007/s00109-005-0718-5
-
Lieb W, Graf J, Gö tz A, Kö nig IR, Mayer B, Fischer M, et al. Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men. Results of the MONICA Augsburg echocardiographic substudy. J Mol Med 2006; 84:88-96. (Pubitemid 43099527)
-
(2006)
Journal of Molecular Medicine
, vol.84
, Issue.1
, pp. 88-96
-
-
Lieb, W.1
Graf, J.2
Gotz, A.3
Konig, I.R.4
Mayer, B.5
Fischer, M.6
Stritzke, J.7
Hengstenberg, C.8
Holmer, S.R.9
Doring, A.10
Lowel, H.11
Schunkert, H.12
Erdmann, J.13
-
23
-
-
26044453206
-
Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats
-
DOI 10.1113/expphysiol.2005.031096
-
Huentelman MJ, Grobe JL, Vazquez J, Stewart JM, Mecca AP, Katovich MJ, et al. Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats. Exp Physiol 2005; 90:783-790. (Pubitemid 41406067)
-
(2005)
Experimental Physiology
, vol.90
, Issue.5
, pp. 783-790
-
-
Huentelman, M.J.1
Grobe, J.L.2
Vazquez, J.3
Stewart, J.M.4
Mecca, A.P.5
Katovich, M.J.6
Ferrario, C.M.7
Raizada, M.K.8
-
24
-
-
0031950818
-
Tissue angiotensin II concentration in the heart and kidneys in transgenic Tsukuba hypertensive mice
-
DOI 10.1080/080370598437583
-
Kai T, Shimada S, Kurooka A, Takenaka T, Ishikawa K. Tissue angiotensin II concentration in the heart and kidneys in transgenic Tsukuba hypertensive mice. Blood Press 1998; 7:61-63. (Pubitemid 28137528)
-
(1998)
Blood Pressure
, vol.7
, Issue.1
, pp. 61-63
-
-
Kai, T.1
Shimada, S.2
Kurooka, A.3
Takenaka, T.4
Ishikawa, K.5
-
26
-
-
77952511816
-
Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats
-
Trask AJ, Groban L, Westwood BM, Varagic J, Ganten D, Gallagher PE, et al. Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats. Am J Hypertens 2010; 23:687-693.
-
(2010)
Am J Hypertens
, vol.23
, pp. 687-693
-
-
Trask, A.J.1
Groban, L.2
Westwood, B.M.3
Varagic, J.4
Ganten, D.5
Gallagher, P.E.6
-
27
-
-
33644653008
-
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart
-
Castro CH, Santos RA, Ferreira AJ, Bader M, Alenina N, Almedia AP. Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart. Hypertension 2005; 46:937-942.
-
(2005)
Hypertension
, vol.46
, pp. 937-942
-
-
Castro, C.H.1
Santos, R.A.2
Ferreira, A.J.3
Bader, M.4
Alenina, N.5
Almedia, A.P.6
-
28
-
-
33847018997
-
Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways
-
DOI 10.1161/01.HYP.0000251865.35728.2f, PII 0000426820070100000034
-
Sampaio WO, Souza dos Santos RA, Faria-Sliva R, da Mata Machado LT, Schiffrin EL, Touyz RM. Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways. Hypertension 2007; 49:185-192. (Pubitemid 46360359)
-
(2007)
Hypertension
, vol.49
, Issue.1
, pp. 185-192
-
-
Sampaio, W.O.1
Dos Santos, R.A.S.2
Faria-Silva, R.3
Da Mata Machado, L.T.4
Schiffrin, E.L.5
Touyz, R.M.6
-
29
-
-
34547123088
-
Angiotensin II-mediated oxidative stress promotes myocardial tissue remodeling in the transgenic (mRen2) 27 Ren2 rat
-
DOI 10.1152/ajpendo.00632.2006
-
Whaley-Connell A, Govindarajan G, Habibi J, Hayden MR, Cooper SA, Wei Y, et al. Angiotensin II-mediated oxidative stress promotes myocardial tissue remodeling in the transgenic (mRen2) 27 Ren2 rat. Am J Physiol Endocrinol Metab 2007; 293:E355-E363. (Pubitemid 47105951)
-
(2007)
American Journal of Physiology - Endocrinology and Metabolism
, vol.293
, Issue.1
-
-
Whaley-Connell, A.1
Govindarajan, G.2
Habibi, J.3
Hayden, M.R.4
Cooper, S.A.5
Wei, Y.6
Ma, L.7
Qazi, M.8
Link, D.9
Karuparthi, P.R.10
Stump, C.11
Ferrario, C.12
Sowers, J.R.13
-
30
-
-
33745202365
-
NADPH oxidase-dependent redox signaling in cardiac hypertrophy, remodeling and failure
-
Murdoch CE, Zhang M, Cave AC, Shah AM. NADPH oxidase-dependent redox signaling in cardiac hypertrophy, remodeling and failure. Cardiovasc Res 2006; 71:208-215.
-
(2006)
Cardiovasc Res
, vol.71
, pp. 208-215
-
-
Murdoch, C.E.1
Zhang, M.2
Cave, A.C.3
Shah, A.M.4
-
31
-
-
34249900226
-
Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice
-
DOI 10.1016/j.cardiores.2007.04.007, PII S0008636307001903
-
Oudit GY, Kassiri Z, Patel MP, Chappell M, Butany J, Backx PH, et al. Angiotensin II-mediated oxidative stress and inflammation mediate the agedependent cardiomyopathy in ACE2 null mice. Cardiovasc Res 2007; 75:29-39. (Pubitemid 46873522)
-
(2007)
Cardiovascular Research
, vol.75
, Issue.1
, pp. 29-39
-
-
Oudit, G.Y.1
Kassiri, Z.2
Patel, M.P.3
Chappell, M.4
Butany, J.5
Backx, P.H.6
Tsushima, R.G.7
Scholey, J.W.8
Khokha, R.9
Penninger, J.M.10
-
32
-
-
73849117533
-
Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus
-
Gwathmey TM, Pendergrass KD, Reid SD, Rose JC, Diz DI, Chappell MC. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension 2010; 55:166-171.
-
(2010)
Hypertension
, vol.55
, pp. 166-171
-
-
Gwathmey, T.M.1
Pendergrass, K.D.2
Reid, S.D.3
Rose, J.C.4
Diz, D.I.5
Chappell, M.C.6
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