Reactivation of organophosphate-inhibited human acetylcholinesterase by isonitrosoacetone (MINA): A kinetic analysis

Chemico-Biological Interactions

Volumn 194, Issue 2-3, 2011, Pages 91-96

  Worek, Franz ^a   Thiermann, Horst ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

Author keywords

Acetylcholinesterase; Isonitrosoacetone; Kinetics; Organophosphorus compounds; Oximes; Reactivation

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ACETYLCHOLINESTERASE; CYCLOSARIN; ISONITROSOACETONE; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; OBIDOXIME; ORGANOPHOSPHATE; OXIME; PARAOXON; PRALIDOXIME; SARIN; TABUN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME KINETICS; ENZYME REACTIVATION; HUMAN; IN VITRO STUDY;

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; ENZYME ACTIVATION; HUMANS; KINETICS; ORGANOPHOSPHORUS COMPOUNDS; OXIMES;

ANIMALIA; CAVIA;

EID: 80054084469     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.09.001     Document Type: Article

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