The role of bile acid retention and a common polymorphism in the ABCB11 gene as host factors affecting antiviral treatment response in chronic hepatitis C

Journal of Viral Hepatitis

Volumn 18, Issue 11, 2011, Pages 768-778

  Iwata, R ^a   Stieger, B ^a,b   Mertens, J C ^a   Muller T ^c   Baur, K ^a   Frei, P ^a   Braun, J ^d   Vergopoulos, A ^a   Martin, I V ^a,e   Schmitt, J ^a   Goetze, O ^a   Bibert, S ^f   Bochud, P Y ^f   Mullhaupt B ^a   Berg, T ^c   Geier, A ^a,b,g  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^f UNIVERSITY OF LAUSANNE   (Switzerland)

^g UNIVERSITY HOSPITAL LEIPZIG   (Germany)

Author keywords

BSEP; FXR; genetics; HCV; interferon response

Indexed keywords

ABC TRANSPORTER; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; BILE ACID; GAMMA GLUTAMYLTRANSFERASE; INTERLEUKIN 28B; PEGINTERFERON; PROTEIN ABCB11; RIBAVIRIN; UNCLASSIFIED DRUG; VIRUS RNA;

ADULT; AGED; ARTICLE; BILE ACID BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GENE FREQUENCY; GENOTYPE; HEPATITIS C; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE; VIRUS LOAD;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIVIRAL AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; DRUG THERAPY, COMBINATION; FEMALE; GENOTYPE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; INTERFERON-ALPHA; MALE; MIDDLE AGED; POLYETHYLENE GLYCOLS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINANT PROTEINS; RIBAVIRIN; TREATMENT OUTCOME;

EID: 80054083469     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2010.01363.x     Document Type: Article

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