Ribosome display selection of a murine IgG1 fab binding affibody molecule allowing species selective recovery of monoclonal antibodies

Molecular Biotechnology

Volumn 48, Issue 3, 2011, Pages 263-276

  Grimm, Sebastian ^a   Yu, Feifan ^a   Nygren, Per Åke ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Affibody; Combinatorial protein engineering; Fab fragment; Mouse IgG1; Ribosome display; Selection

Indexed keywords

AFFIBODY; COMBINATORIAL PROTEIN ENGINEERING; FAB FRAGMENTS; MOUSE IGG; RIBOSOME DISPLAY; SELECTION;

BINDERS; DISSOCIATION; GENETIC ENGINEERING; MAMMALS; MONOCLONAL ANTIBODIES; SURFACE PLASMON RESONANCE;

MACROMOLECULES;

BACTERIAL PROTEIN; BOVINE SERUM ALBUMIN; EPITOPE; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY; PAPAIN; HYBRID PROTEIN; IMMUNOGLOBULIN G;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOSENSOR; CONTROLLED STUDY; HYBRIDOMA CELL CULTURE; IN VITRO SELECTION; MOLECULAR LIBRARY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; RIBOSOME; AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY COMBINING SITE; BIOLOGICAL MODEL; CATTLE; CHEMISTRY; COMBINATORIAL CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC PROCEDURES; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN ENGINEERING; SPECIES DIFFERENCE; WESTERN BLOTTING;

BOVINAE; MURINAE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; BIOSENSING TECHNIQUES; BLOTTING, WESTERN; CATTLE; CHROMATOGRAPHY, AFFINITY; COMBINATORIAL CHEMISTRY TECHNIQUES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN G; IMMUNOSORBENT TECHNIQUES; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PAPAIN; PROTEIN BINDING; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; RIBOSOMES; SPECIES SPECIFICITY;

EID: 80054079725     PISSN: 10736085     EISSN: 15590305     Source Type: Journal    
DOI: 10.1007/s12033-010-9367-1     Document Type: Article

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