Sensitivity and specificity of the UCSD Performance-based Skills Assessment (UPSA-B) for identifying functional milestones in schizophrenia

Schizophrenia Research

Volumn 132, Issue 2-3, 2011, Pages 165-170

  Mausbach, Brent T ^a   Depp, Colin A ^a   Bowie, Christopher R ^b   Harvey, Philip D ^c   McGrath, John A ^d   Thronquist, Mary H ^b   Luke, James R ^b   Wolyniec, Paula S ^b   Pulver, Ann E ^b   Patterson, Thomas L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b QUEEN S UNIVERSITY   (Canada)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Employment; Functional capacity; Functioning; Independence; Psychosis; Well being

Indexed keywords

CHLORPROMAZINE;

ADULT; AGED; ARTICLE; BRIEF UCSD PERFORMANCE BASED SKILLS ASSESSMENT; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; EMPLOYMENT STATUS; FEMALE; FUNCTIONAL ASSESSMENT; FUNCTIONAL STATUS; HUMAN; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PREDICTION; PRIORITY JOURNAL; RESIDENTIAL CARE; SCHIZOPHRENIA; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

ADULT; AGED; EMPLOYMENT; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PSYCHOMOTOR PERFORMANCE; REPRODUCIBILITY OF RESULTS; RESIDENCE CHARACTERISTICS; ROC CURVE; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; YOUNG ADULT;

EID: 80054073464     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2011.07.022     Document Type: Article

References (31)

1. American Psychiatric Association Practice guidelines for the treatment of patients with schizophrenia 2004.
2. Andreasen N.C., Pressler M., Nopoulos P., Miller D., Ho B.C. Antipsychotic dose equivalents and dose-years: a standardized method for comparing exposure to different drugs. Biol. Psychiatry 2010, 67:255-262.
3. Bowie C.R., Reichenberg A., Patterson T.L., Heaton R.K., Harvey P.D. Determinants of real-world functioning performance in Schizophrenia: correlations with cognition, functional capacity, and symptoms. Am. J. Psychiatry 2006, 163:418-425.
4. Bowie C.R., Leung W.W., Reichenberg A., McClure M.M., Patterson T.L., et al. Predicting schizophrenia patients' real-world behavior with specific neuropsychological and functional capacity measures. Biol. Psychiatry 2008, 63:505-511.
5. Bray S.M., Mulle J.G., Dodd A.F., Pulver A.E., Wooding S., Warren S.T. Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:16222-16227.
6. Chen P.L., Avramopoulos D., Lasseter V.K., McGrath J.A., Fallin M.D., et al. Fine mapping on chromosome 10q22-q23 implicates Neuregulin 3 in schizophrenia. Am. J. Hum. Genet. 2009, 84:21-34.
7. Deeks J. Systematic reviews of evaluations of diagnostic and screening tests. BMJ 2001, 323:7305.
8. Fallin M.D., Lasseter V.K., Wolyniec P.S., McGrath J.A., Nestadt G., et al. Genomewide linkage scan for schizophrenia susceptibility loci among Ashkenazi Jewish families shows evidence of linkage on chromosome 10q22. Am. J. Hum. Genet. 2003, 73:601-611.
9. Fallin M.D., Lasseter V.K., Wolyniec P.S., McGrath J.A., Nestadt G., et al. Genomewide linkage scan for bipolar-disorder susceptibility loci among Ashkenazi Jewish families. Am. J. Hum. Genet. 2004, 75:204-219.
10. Fallin M.D., Lasseter V.K., Avramopoulos D., Nicodemus K.K., Wolyniec P.S., et al. Bipolar I disorder and schizophrenia: A 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Am. J. Hum. Genet. 2005, 77:918-936.
11. Fan J., Upadhye S., Worster A. Understanding receiver operating characteristic (ROC) curves. Can. J. Emerg. Med. 2006, 8:19-20.
12. Green M.F. What are the functional consequences of neurocognitive deficits in schizophrenia?. Am. J. Psychiatry 1996, 153:321-330.
13. Green M.F., Kern R.S., Braff D.L., Mintz J. Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the "right stuff"?. Schizophr. Bull. 2000, 26:119-136.
14. Green M.F., Schooler N.R., Kern R.S., Frese F.J., Granberry W., et al. Evaluation of functionally meaningful measures for clinical trials of cognition enhancement in schizophrenia. Am. J. Psychiatry 2011, 168:400-407.
15. Green M.F., Schooler N.R., Kern R.S., Frese F.J., Granberry W., et al. Evaluation of functionally meaningful measures for clinical trials of cognition enhancement in schizophrenia. Am. J. Psychiatry 2011, 168:400-407.
16. Harvey P.D., Velligan D.I., Bellack A.S. Performance-based measures of functional skills: usefulness in clinical treatment studies. Schizophr. Bull. 2007, 33:1138-1148.
17. Harvey P.D., Helldin L., Bowie C.R., Heaton R.K., Olsson A.K., et al. Performance-based measurement of functional disability in schizophrenia: a cross-national study in the United States and Sweden. Am. J. Psychiatry 2009, 166:821-827.
18. Harvey PD, Raykov T, Twamley E, Vella L, Heaton RK, Patterson TL, in press. Validating the measurement of real-world functional outcomes: Phase 1 results of the VALERO study. Am J Psychiatry.
19. Kay S.R., Fiszbein A., Opler L.A. The Positive And Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr. Bull. 1987, 13:261-276.
20. Liberman R.P. Assessment of social skills. Schizophr. Bull. 1982, 8:62-83.
21. Mausbach B.T., Harvey P.D., Goldman S.R., Jeste D.V., Patterson T.L. Development of a brief scale of everyday functioning in persons with serious mental illness. Schizophr. Bull. 2007, 33:1364-1372.
22. Mausbach B.T., Bowie C.R., Harvey P.D., Twamley E.W., Goldman S.R., et al. Usefulness of the UCSD Performance-based Skills Assessment (UPSA) for predicting residential independence in patients with chronic schizophrenia. J. Psychiatr. Res. 2008, 42:320-327.
23. Mausbach B.T., Depp C.A., Cardenas V., Jeste D.V., Patterson T.L. Relationship between functional capacity and community responsibility in patients with schizophrenia: differences between independent and assisted living settings. Community Ment. Health J. 2008, 44:385-391.
24. Mausbach B.T., Moore R., Bowie C., Cardenas V., Patterson T.L. A review of instruments for measuring functional recovery in those diagnosed with psychosis. Schizophr. Bull. 2009, 35:307-318.
25. McGurk S.R., Mueser K.T. Cognitive functioning, symptoms, and work in supported employment: a review and heuristic model 2004, 70:147-173.
26. McIntosh B.J., Zhang X.Y., Kosten T., Tan S.P., Xiu M.H., et al. Performance-based assessment of functional skills in severe mental illness: Results of a large-scale study in China. J. Psychiatr. Res. 2011, 45:1089-1094.
27. Patterson T.L., Mausbach B.T. Measurement of functional capacity: a new approach to understanding functional differences and real-world behavioral adaptation in those with mental illness. Annu. Rev. Clin. Psychol. 2010, 6:139-154.
28. Rosenheck R., Leslie D., Keefe R., McEvoy J., Swartz M., et al. Barriers to employment for people with schizophrenia. Am. J. Psychiatry 2006, 163:411-417.
29. Salkever D.S., Karakus M.C., Slade E.P., Harding C.M., Hough R.L., et al. Measures and predictors of community-based employment and earnings of persons with schizophrenia in a multisite study 2007, 58:315-324.
30. Twamley E.W., Doshi R.R., Nayak G.V., Palmer B.W., Golshan S., et al. Generalized cognitive impairments, ability to perform everyday tasks, and level of independence in community living situations of older patients with psychosis. Am. J. Psychiatry 2002, 159:2013-2020.
31. Youden W.J. Index for rating diagnostic tests. Cancer 1950, 3:32-35.