Topological basis of epileptogenesis in a model of severe cortical trauma

Journal of Neurophysiology

Volumn 106, Issue 4, 2011, Pages 1933-1942

  Volman, Vladislav ^a,b   Sejnowski, Terrence J ^a,b,c   Bazhenov, Maxim ^a,d  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Homeostatic plasticity; Paroxysmal discharge; Seizure

Indexed keywords

ANTIDROMIC STIMULATION; ARTICLE; CELL DENSITY; DEAFFERENTATION; ELECTRIC ACTIVITY; EPILEPTIC DISCHARGE; EPILEPTOGENESIS; HOMEOSTASIS; MATHEMATICAL MODEL; NERVE CELL; NERVE CELL PLASTICITY; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; TRAUMATIC EPILEPSY;

ACTION POTENTIALS; AFFERENT PATHWAYS; CELL SURVIVAL; COMPUTER SIMULATION; EPILEPSY, POST-TRAUMATIC; MODELS, NEUROLOGICAL; NEURAL NETWORKS (COMPUTER); NEURONAL PLASTICITY; NEURONS; POTASSIUM CHANNELS; RECEPTORS, N-METHYL-D-ASPARTATE; SODIUM CHANNELS; SYNAPTIC TRANSMISSION;

EID: 80054033640     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00458.2011     Document Type: Article

References (26)

1. Avramescu S, Timofeev I. Synaptic strength modulation after cortical trauma: a role in epileptogenesis. J Neurosci 28: 6760-6772, 2008.
2. Bogaard A, Parent J, Zochowski M, Booth V. Interaction of cellular and network mechanisms in spatiotemporal pattern formation in neuronal networks. J Neurosci 29: 1677-1687, 2009.
3. Butz M, van Ooyen A, Worgotter F. A model for cortical rewiring following deafferentation and focal stroke. Front Comput Neurosci 3: 10, 2009.
4. de Curtis M, Avanzini G. Interictal spikes in focal epileptogenesis. Prog Neurobiol 63: 541-567, 2001.
5. Dorogovtsev SN, Mendes JFF. Evolution of Networks: from Biological Nets to the Internet and WWW. Oxford, UK: Oxford University Press, 2003.
6. Dyhrfjeld-Johnsen J, Santhakumar V, Morgan RJ, Huerta R, Tsimring L, Soltesz I. Topological determinants of epileptogenesis in large-scale structural and functional models of the dentate gyrus derived from experimental data. J Neurophysiol 97: 1566-1587, 2007.
7. Dzhala VI, Staley KJ. Transition from interictal to ictal activity in limbic networks in vitro. J Neurosci 23: 7873-7880, 2003.
8. Edelstein-Keshet L, Spiros A. Exploring the formation of Alzheimer's disease senile plaques in silico. J Theor Biol 216: 301-326, 2002.
9. Frohlich F, Bazhenov M, Sejnowski TJ. Pathological effect of homeostatic synaptic scaling on network dynamics in diseases of the cortex. J Neurosci 28: 1709-1720, 2008.
10. Grafstein B, Sastry PB. Some preliminary electrophysiological studies on chronic neuronally isolated cerebral cortex. Electroencephalogr Clin Neurophysiol 9: 723-725, 1957.
11. Houweling AR, Bazhenov M, Timofeev I, Steriade M, Sejnowski TJ. Homeostatic synaptic plasticity can explain post-traumatic epileptogenesis in chronically isolated neocortex. Cereb Cortex 15: 834-845, 2005.
12. Jin X, Prince DA, Huguenard JR. Enhanced excitatory synaptic connectivity in layer V pyramidal neurons of chronically injured epileptogenic neocortex in rats. J Neurosci 26: 4891-4900, 2006.
13. Keller CJ, Truccolo W, Gale JT, Eskandar E, Thesen T, Carlson C, Devinsky O, Kuzniecky R, Doyle WK, Madsen JR, Schomer DL, Mehta AD, Brown EN, Hochberg LR, Ulbert I, Halgren E, Cash SS. Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex. Brain 133: 1668-1681, 2010.
14. Lau LT, Yu ACH. Astrocytes produce and release interleukin-1, interleukin- 6, tumor necrosis factor alpha and interferon-gamma following traumatic and metabolic injury. J Neurotrauma 18: 351-359, 2001.
15. Morgan RJ, Soltesz I. Nonrandom connectivity of the epileptic dentate gyrus predicts a major role for neuronal hubs in seizures. Proc Natl Acad Sci USA 105: 6179-6184, 2008.
16. Netoff TI, Clewley R, Arno S, Keck T, White JA. Epilepsy in small-world networks. J Neurosci 24: 8075-8083, 2004.
17. Pitkänen A, Schwartzkroin PA, Moshé SL. (editors) Models of Seizure and Epilepsy. Maryland Heights, MO: Elsevier Science, 2006.
18. Prescott SA, Ratte S, De Koninck Y, Sejnowski TJ. Nonlinear interaction between shunting and adaptation controls a switch between integration and coincidence detection in pyramidal neurons. J Neurosci 26: 9084-9097, 2006.
19. Prince DA, Tseng GF. Epileptogenesis in chronically injured cortex: in vitro studies. J Neurophysiol 69: 1276-1291, 1993.
20. Srinivas KV, Jain R, Saurav S, Sikdar SK. Small-world network topology of hippocampal neuronal network is lost, in an in vitro glutamate injury model of epilepsy. Eur J Neurosci 25: 3276-3286, 2007.
21. Steinmetz CC, Turrigiano GG. Tumor necrosis factor-α signaling maintains the ability of cortical synapses to express synaptic scaling. J Neurosci 30: 14685-14690, 2010.
22. Stellwagen D, Malenka RC. Synaptic scaling mediated by glial TNF-α. Nature 440: 1054-1059, 2006.
23. Timofeev I, Bazhenov M, Avramescu S, Nita DA. Posttraumatic epilepsy: the roles of synaptic plasticity. Neuroscientist 16: 19-27, 2010.
24. Topolnik L, Steriade M, Timofeev I. Partial cortical deafferentation promotes development of paroxysmal activity. Cereb Cortex 13: 883-93, 2003.
25. Turrigiano GG, Leslie KR, Desai NS, Rutherford LC, Nelson SB. Activitydependent scaling of quantal amplitude in neocortical neurons. Nature 391: 892-896, 1998.
26. Wendling F, Hernandez A, Bellanger JJ, Chauvel P, Bartolomei F. Interictal to ictal transition in human temporal lobe epilepsy: insights from a computational model of intracerebral EEG. J Clin Neurophysiol 22: 343-356, 2005.